Open Archive: Publications from Karolinska Institutet
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Antibody-associated inflammation in and outside the joint in rheumatoid arthritis
(Inst för medicin, Solna / Dept of Medicine, Solna, 2017-08-17)Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by pain, chronic inflammation and joint destruction. Epidemiological investigations in large populationbased cohorts have identified both genetic ... -
Global regulation of gene expression in stem cells and regeneration
(Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2017-08-17)Rapid developments in genomics and transcriptomics fields have made it possible to ask new questions as well as solve various old problems in biology that were not achievable previously. Novel techniques such as RNA ... -
Exploring the impact of diabetes in Sudan : out-of-pocket expenditure and social consequences of diabetes on patients and their families
(Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2017-08-10)Diabetes mellitus in Sudan is a growing health problem in all socio-economic classes. The natural history of the disease is associated with poor of glycaemic control, a high prevalence of complications and a low quality ... -
The challenge of co-existence : from graft-versus-host disease to stable mixed chimerism after allogeneic hematopoietic stem cell transplantation
(Inst för onkologi-patologi / Dept of Oncology-Pathology, 2017-08-08)The only curative treatment strategy for many hematologic and inborn immunodeficiency disorders is an allogeneic hematopoietic stem cell transplantation (HSCT). The treatment involves replacing the entire hematopoietic ... -
The matter of white and gray matter in cognitive impairment
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-08-03)Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the ...