• Molecular insights into the pathogenesis of b-cell and myeloid malignancies : therapeutic implications 

  Xia, Chuanyou (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-03)

  Hematological malignancies originate from hematopoietic cells in the bone marrow or the lymphatic system. In this thesis, I study the molecular pathogenesis of Hodgkin lymphoma (HL), mantle cell lymphoma (MCL), and ...

• Health-related quality of life of different patient groups in Swedish national quality registers : longitudinal studies of EQ-5D data and application of different value sets 

  Teni, Fitsum Sebsibe (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2021-03-02)

  Background: EQ-5D data on patients’ health-related quality of life (HRQoL) are collected in roughly 40% of about 100 National Quality Registers (NQRs) in Sweden. The aim of the thesis was to increase knowledge on the use ...

• Antireflux surgery in the prevention of supra-esophageal cancer and mortality 

  Yanes, Manar (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2021-03-02)

  Gastroesophageal reflux disease (GERD), mainly characterized by heartburn or regurgitation, is a common condition in the Western world with an increasing prevalence. GERD is associated with an increased risk of adenocarcinoma ...

• Causes and consequences of stress and tobacco exposure in utero on birth size, asthma and academic achievement 

  Lundholm, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2021-03-01)

  The objective of this thesis was to further the understanding of the consequences of stress and smoking during pregnancy, the causes of intrauterine growth and asthma as well as the consequences of asthma on school ...

• Developmental dynamics of cardiac progenitors and their role in congenital heart defects 

  Mononen, Mimmi (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2021-03-01)

  Cardiac progenitors are the fundamental building blocks of the heart and play a central role in the pathogenesis of congenital heart defects. Recent single-cell RNA sequencing studies have revealed that the cell populations ...

View more