Karolinska Institutet Open Archive
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Trends in population health in an era of increasing longevity
(Institutet för miljömedicin / Institute of Environmental Medicine, 2022-01-26)In Sweden, the number of older adults over the age of 85 increased by 75% since 1990 while the number of centenarians has almost quadrupled. Rapid population ageing is a global phenomenon and projected to continue in almost ... -
Pelvic pain due to endometriosis and dysmenorrhea
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2022-01-24)Background Approximately 70% of women in reproductive age suffer from dysmenorrhea around the world but no prevalence study has been made in Sweden for 35 years. Dysmenorrhea, painful menstruation, can be a sign of ... -
Point-of-care diagnostics of childhood central nervous system infections, with a focus on usability in low-resource settings
(Inst för global folkhälsa / Dept of Global Public Health, 2022-01-24)Background: The inaccessibility of laboratory services sustains the high burden of paediatric infectious diseases, such as central nervous system (CNS) infections, in low-resource settings. New contextually fit and ... -
Anterior cruciate ligament injuries in football
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2022-01-21)Anterior cruciate ligament (ACL) injuries and football are clearly intertwined. ACL injuries are principally sustained when participating in pivoting activities and, as it is such a popular sport, football is consequently ... -
Developing and democratizing tools for spatially resolved profiling of genome and transcriptome
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2022-01-21)The common thread of the work presented in this thesis is the development and democratization of tools that facilitate the spatial profiling of genome and transcriptome. Paper I1 describes iFISH, a resource that ...