• Sensitivity of Salmonella YG5161 for detecting PAH-associated mutagenicity in air particulate matter. 

  Umbuzeiro, GA; Kummrow, F; Morales, D.A.; Alves, DK; Lim, H; Jarvis, Ian WH; Bergvall, Christoffer; Westerholm, Roger; Stenius, Ulla; Dreij, K (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-07-07)

  The Salmonella/microsome assay is the most used assay for the evaluation of air particulate matter (PM) mutagenicity and a positive correlation between strain TA98 responses and benzo[a]pyrene (B[a]P) levels ...

• Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment. 

  Jarvis, Ian WH; Dreij, Kristian; Mattsson, Å; Jernström, B; Stenius, Ulla (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-07-07)

  In this review we discuss the effects of exposure to complex PAH mixtures in vitro and in vivo on mechanisms related to carcinogenesis. Of particular concern regarding exposure to complex PAH mixtures is how ...

• Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells. 

  Jarvis, Ian WH; Bergvall, Christoffer; Morales, D.A.; Kummrow, F; Umbuzeiro, GA; Westerholm, Roger; Stenius, Ulla; Dreij, Kristian (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-07-07)

  Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that occur naturally in complex mixtures. Many of the adverse health effects of PAHs including cancer are linked to the activation ...

• Benzo[a]pyrene-specific online high-performance liquid chromatography fractionation of air particulate extracts : a tool for evaluating biological interactions. 

  Lim, H; Bergvall, Christoffer; Jarvis, Ian WH; Mattsson, Å; Dreij, Kristian; Stenius, Ulla; Westerholm, Roger (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-07-07)

  Benzo[a]pyrene (B[a]P) is a known human carcinogen and is commonly used as a surrogate for assessing the carcinogenic risk posed by complex mixtures of polycyclic aromatic hydrocarbons (PAHs) present in air ...

• Shared familial risk factors between attention-deficit/hyperactivity disorder and overweight/obesity : a population based familial co-aggregation study in Sweden 

  Chen, Qi; Kuja-Halkola, Ralf; Sjölander, Arvid; Serlachius, Eva; Cortese, Samuele; Faraone, Stephen V.; Almqvist, Catarina; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-07-07)

  BACKGROUND: Despite meta-analytic evidence for the association between attention-deficit/hyperactivity disorder (ADHD) and overweight/obesity, the mechanisms underlying the association are yet to be fully ...

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