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  • Immunological mechanisms regulating neuroinflammation : a role for C-type lectin receptors and vitamin D 

    N'diaye, Marie (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2018-02-20)
    Autoimmunity of the central nervous system (CNS) such as in Multiple Sclerosis (MS) or its animal model Experimental Autoimmune Encephalomyelitis (EAE) requires the activation of self-reactive immune cells and the presentation ...
  • Biomarkers for eligibility and surrogate endpoints in heart failure trials 

    Savarese, Gianluigi (Inst för medicin, Solna / Dept of Medicine, Solna, 2018-02-20)
    Background: In heart failure (HF) with reduced ejection fraction (HFrEF), randomized controlled trials have provided effective treatments, but prognosis still remains poor. HF with mid-range EF (HFmrEF) has no ...
  • Regulation of whole-body glucose and lipid metabolism by skeletal muscle 

    Schönke, Milena (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2018-02-16)
    BSTRACT Obesity and associated diseases like type 2 diabetes are rapidly growing health concerns across the globe. The uptake and expenditure of energy in the body are tightly regulated by a plethora of enzymes and ...
  • Novel therapeutic targets in pediatric neural tumors 

    Milosevic, Jelena (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-02-16)
    The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. The ...
  • Characterisation of newt neural stem cells during development and regeneration 

    Liyakath Ali, Shahul Hameed (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2018-02-15)
    The adult newt brain has a unique potential to regenerate neurons after injury. Ependymoglial cells that line the ventricular system of the newt brain are critical for neuronal regeneration, since they reenter the cell ...

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