• The role of RFX transcription factors in neurons and in the human brain 

  Sugiaman, Debora (Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2018-08-15)

  RFX transcription factors (TFs) are conserved in animals, fungi and some amoebae, but not in algae, plants and protozoan species. The conservation is based on the protein sequence of the DNA binding domain (DBD). The RFX ...

• Improving surgical therapy for oesophageal cancer 

  Markar, Sheraz Rehan (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2018-08-14)

  Despite advances in multimodality treatment, surgery remains the mainstay of curative treatment for oesophageal cancer. However short- and long-term mortality from oesophagectomy for oesophageal cancer still shows large ...

• Redox alterations in inflammatory diseases : diabetes, kidney failure and cancer 

  Nair, Deepika (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2018-08-10)

  In order to combat oxidative stress and maintain the intracellular redox homeostasis, cells are equipped with antioxidant systems. The thioredoxin and glutaredoxin systems are the major thiol reducing systems and central ...

• Immune mechanisms in chronic rheumatic muscle inflammation, myositis 

  Tang, Quan (Inst för medicin, Solna / Dept of Medicine, Solna, 2018-08-10)

  The idiopathic inflammatory myopathies (IIM), shortly named myositis, is a group of heterogeneous and rare autoimmune diseases with the target tissue of skeletal muscle. It is not curable and affects the daily life of ...

• Renal dysfunction in heart failure : insights on prevalence and prognosis 

  Löfman, Ida (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2018-08-10)

  Background Kidney disease is common in heart failure (HF) and has been found to be associated with worse outcomes. The impact of different degrees of chronic kidney disease (CKD) in HF, as well as the link to, and ...

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