• Streptococcal and staphylococcal tissue infections: therapeutic challenges and opportunities 

  Bergsten, Helena (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2021-11-26)

  Streptococcus pyogenes and Staphylococcus aureus have been leading causes of human infections throughout history. S. pyogenes is of the top-ten pathogens responsible for most death globally, 0.5 million deaths per year. ...

• Measurement and valuation of health among children and adolescents using the EQ-5D-Y : Methodological considerations and implications 

  Åström, Mimmi (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2021-11-26)

  Introduction: Around the world, life expectancy is increasing but not all years are lived in full health. Hence it is important to look beyond survival rates and also measure healthrelated quality of life. Measurement ...

• Translational studies on Alzheimer's disease : a focus on cholesterol metabolism, Thioredoxin-80 and microglia function 

  Goicolea, Julen (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-26)

  Disturbances in cholesterol metabolism and inflammatory processes may have a negative impact on brain health. These two aspects are considered to be signs of early changes in Alzheimer’s Disease (AD). However, clear ...

• Alzheimer disease : a super-resolved picture of the amyloid β-peptide producing machinery 

  Yu, Yang (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-26)

  Alzheimer disease (AD) is the most common neurodegenerative disease, influencing 40 million patients in the world. Pathologically, AD is hallmarked by intracellular tau tangles and extracellular Amyloid-β peptide (Aβ) ...

• The DNA repair enzymes MTH1 and OGG1 as targets to treat inflammation 

  Karsten, Stella (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-11-25)

  Chronic and acute inflammatory diseases, such as multiple sclerosis (MS), psoriasis and sepsis, account for vast disability and morbidity in the world. Several new immunomodulating treatment alternatives have been developed ...

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