Open Archive: Publications from Karolinska Institutet
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Immune response and tumour cell detection in lymph nodes of head and neck cancer
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-10-18)Many patients with head and neck squamous cell carcinoma present with regional spread to the cervical lymph nodes. Lymph nodes metastases are today the most important factor influencing both the treatment and outcome for ... -
Novel insights into dishevelled and frizzled function
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2018-10-18)The formation of a multicellular body during embryonic development is one of the most fascinating processes in biology. The cells are in constant communication and must be precisely coordinated. Several essential signalling ... -
Patient and organisational perspectives of initial trauma care
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2018-10-18)Physical trauma is one of the major causes of death and disability worldwide. In Sweden a similar pattern can be seen despite having a well-organised health-care system. Improvements in trauma care can increase survival ... -
Innate immune factors in recurrent and persistent infections of the lower female genital tract
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2018-10-18)Background: Infections of the female genital tract are common and have severe impact on the quality of life and sexual health of affected women. The innate immune system is crucial and is involved in the defense of infections. ... -
Role of GPS2 in epigenome alterations linked to metaflammation
(Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2018-10-18)Current evidence suggests that transcriptional and epigenomic reprogramming events, triggered by transcription factors and chromatin-modifying co-regulators, are of central importance for disease development. G-protein ...