Karolinska Institutet Open Archive
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Too tired to talk? Sleep, fatigue, and social functioning
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-21)Sleep has been shown to have many health promoting functions, and is vital for the maintenance of physiological, cognitive, and emotional well-being. Much of what we know about sleep derives from studies showing what happens ... -
Translational investigations of novel and current antitumoral therapies in gastrointestinal stromal tumors
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-11-21)Gastrointestinal stromal tumor (GIST) is the most common human sarcoma. Its incidence is around 10-15 per million person-years, translating into 150 new cases each year in Sweden. The molecular background for the absolute ... -
Definition of immunoglobulin germline genes by next generation sequencing for studies of antigen-specific b cell responses
(Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2019-11-21)Immunoglobulins play a critical role in the adaptive immune system, existing as cell surface-expressed B cell receptors and secreted antibodies. Circulating antibodies are the main correlate of protective immunity for most ... -
Single cell analysis of iPS derived neural stem cells and neurons
(Inst för neurovetenskap / Dept of Neuroscience, 2019-11-21)In vitro derived neural stem cells can be used to model events of neurogenesis and neurodevelopmental dysfunction. Formation of stable neural stem cell environments relies on cellular components to stabilize cell-to-cell ... -
Web-based ECG education : utility and usage in undergraduate medical education
(Inst för medicin, Solna / Dept of Medicine, Solna, 2019-11-20)Investigating the heart with an electrocardiogram (ECG) is an important, frequent and noninvasive investigation. Failure to correctly interpret the ECG may harm the patient. Learning to interpret ECGs is difficult for ...