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  • Roles of NUDT5 and NUDT15 beyond oxidized nucleotide sanitation and their potential as therapeutic targets 

    Valerie, Nicholas Carl Kristoffer (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2018-03-15)
    The nucleotide precursor pool is readily susceptible to numerous sources of modification and damage, including alkylation, deamination and oxidation/nitrosylation, among others; most of which have deleterious effects on ...
  • Clinical and oncopreventive outcomes of antireflux surgery 

    Maret-Ouda, John (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2018-03-15)
    Gastro-oesophageal reflux disease (GORD), with heartburn and acid regurgitation as main symptoms, is a common disease with increasing prevalence. GORD is associated with oesophageal adenocarcinoma, a cancer with demanding ...
  • Novel methods for dose-response meta-analysis 

    Crippa, Alessio (Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2018-03-14)
    Dose–response meta-analysis is a statistical procedure for combining and contrasting the evidence on the association between a continuous exposure and the risk of a health outcome. Different papers refined selected aspects ...
  • Fatal attraction : NK cell migration toward and activity in solid tumors 

    Kremer, Veronika (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2018-03-14)
    Natural killer (NK) cells play a key role in tumor immunosurveillance due to their ability to induce apoptosis of tumor cells and produce pro-inflammatory cytokines, without prior immune sensitization. In particular, NK ...
  • Idiopathic polyneuropathy : a pathogenetic study 

    Samuelsson, Kristin (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2018-03-13)
    Polyneuropathy (PNP) stands for dysfunction in the peripheral nerves. The classical clinical manifestations of PNP are distal, symmetric sensory symptoms, such as numbness and pain, as well as distal weakness in a sock- ...

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