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  • Specification and potency of human neural stem cells for clinical transplantation 

    Vincent, Per Henrik (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-24)
    Neural stem cells hold promise for future treatment of spinal cord injury. Various aspects regarding cell fate specification, manufacturing and monitoring, with implications for clinical applications of these cells, are ...
  • Primary care patients with common mental disorders : quality of life, sick leave and effects of group therapy 

    Ejeby, Kersti (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-19)
    Background: Depression, Anxiety and Stress-Related Disorders, Common Mental Disorders (CMDs) are common among patients in primary health care, with many left untreated or even undiagnosed. CMDs are associated with high ...
  • How well are we aging? : capturing the complexity of health trajectories of older adults 

    Santoni, Giola (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-12)
    Despite its positive nature, population aging represents a public health challenge that could be alleviated by maintaining good health during older age. The aim of this thesis was to evaluate how well people are aging, ...
  • Neuroimaging biomarkers in Alzheimer’s disease 

    Falahati Asrami, Farshad (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-11)
    Alzheimer’s disease (AD) is characterized by an accumulation of abnormal plaques and tangles in the brain, a process that is estimated to begin years before the appearance of clinical symptoms. Individuals with subjective ...
  • Depression & cognition in the elderly : neuroimaging perspective 

    Lebedeva, Aleksandra (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-03)
    This thesis examines the relationship between depression and brain structure in the elderly with (Study I, III) and without (Study II, IV) cognitive impairment (Alzheimer’s disease and mild cognitive impairment). Individuals ...
  • Lifestyle, cognitive aging, and brain correlates 

    Köhncke, Ylva (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-04-28)
    Inter-individual differences in level and rate of cognitive decline typically seen in aging have been linked to inter-individual differences in lifestyle factors such as leisure activities, including physical activity. The ...
  • The influence of sex hormones on neuromuscular function and premenstrual symptoms 

    Ekenros, Linda (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-04-13)
    The menstrual cycle with fluctuation in female sex hormones has been suggested to influence neuromuscular function. However, variation in ligament laxity, soft tissue stiffness, and skeletal muscle strength across the ...
  • Vårdskador vid omvårdnad : en studie av patienters, anhörigas och vårdgivares anmälningar 

    Andersson, Åsa (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-23)
    Background: Patient safety has, over the last decades, been increasingly established as an important global issue. Patient safety is jeopardized by for example adverse events and most of the current evidence on adverse ...
  • Elderly patients undergoing colorectal cancer surgery : can care be further improved? 

    Schubert Samuelsson, Katja (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-17)
    Introduction: Colorectal cancer (CRC) is one of the most common malignancies affecting approximately 6 400 new patients/year in Sweden of which 44% are 75 years and older at diagnosis. In order to identify potential ...
  • Genetic and lifestyle influences on memory, brain structure, and dementia 

    Ferencz, Beata (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-16)
    This doctoral thesis investigated genetic, inflammatory, and lifestyle influences on cognition, brain structure, and dementia. The influence of TOMM40 polymorphisms (Study I), a PICALM, BIN1 and CLU genetic risk score ...
  • Apolipoprotein E and cholinergic enzymes : the interface in dementia 

    Vijayaraghavan, Swetha (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-10)
    The main confirmed genetic risk factor for sporadic form of Alzheimer’s disease (AD) is apolipoprotein E (ApoE) ε4 allele (APOE4). ApoE protein aids in receptor ligand mediated transport, distribution and metabolism of ...
  • Falls in wheelchair users with spinal cord injury : incidence, risks and concerns 

    Butler Forslund, Emelie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-02)
    Background: Knowledge about falls and related injuries in persons with spinal cord injuries (SCI) is limited, especially concerning wheelchair users. Further research is required in order to develop future prevention ...
  • Meaning-making in integrative health care : studies on patients’ and practitioners’ experiences 

    Andermo, Susanne (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-01)
    Background and aim: Patients living with chronic pain often turn both to conventional and complementary health care. Integrative health care combines conventional and complementary therapies in the clinical care of ...
  • Hatha yogic exercises for physical function in healthy individuals and patients with obstructive respiratory disorders 

    Papp, Marian E (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-01-27)
    Background and aim: The use of hatha yogic exercises (YE) is increasing, with both healthy individuals and patients asking for alternative treatments and other means of prevention and exercise. To investigate the physical ...
  • Nerve growth factor in Alzheimer’s disease : biological effects and therapeutic potential 

    Eyjolfsdottir, Helga (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-01-12)
    Alzheimer’s disease (AD) is a progressive neurodegenerative disorder against which there is yet no disease modifying or curative treatment. Degeneration of cholinergic basal forebrain (CBF) neurons plays a role in the ...
  • Att vara fysiskt aktiv under adjuvant cytostatikabehandling : interventionsstudier för personer med bröst - och kolorektalcancer 

    Backman, Malin (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-01-12)
    Bakgrund: Regelbunden fysisk aktivitet har sedan länge visat sig vara viktigt för att upprätthålla en god hälsa hos människor och det är känt att fysisk inaktivitet är en betydande riskfaktor för en rad olika hälsoproblem ...
  • Cardiovascular disease in dementia 

    Cermakova, Pavla (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-12-08)
    The objective of this thesis was to characterize the burden of cardiovascular diseases in patients with dementia, their treatment and association with survival. Further, we aimed to explore whether cardiac structure in ...
  • The process of occupational therapists implementing client-centred ADL intervention in clinical practice 

    Eriksson, Christina Nilsdotter (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-11-22)
    The overall aim: The overall aim of the thesis was to identify and describe the characteristics of the implementation process and what hinders and contributes to the implementation of complex interventions when occupational ...
  • Physical activity in Parkinson’s disease : measurement, correlates and effects of balance training 

    Nero, Håkan (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-11-21)
    Aim: The overall aim of this thesis was to investigate correlates of physical activity in older adults with Parkinson’s disease and to evaluate the effects, both short- and long term, of the HiBalance program on physical ...
  • The quality of the physical environment and its association with activities and well-being among older people in residential care facilities 

    Nordin, Susanna (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-11-21)
    The physical environment can influence older people’s health and well-being, and is often mentioned as being an important factor for person-centred care. Due to high levels of frail health, many older people spend a majority ...

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