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  • Pediatric obstructive sleep apnea - evaluation of questionnaire and surgical treatment 

    Borgström, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-23)
    Obstructive sleep apnea (OSA) is a major pediatric health problem and is associated with potentially severe consequences if left untreated. Diagnosing OSA in children can be challenging since the clinical symptoms are ...
  • Liver regeneration and function following portal vein occlusion and hepatectomy 

    Sparrelid, Ernesto (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-06)
    Background: Portal vein occlusion (PVO) and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) are two strategies employed to render patients with unresectable liver tumours resectable ...
  • Studies of drug disposition in hemodialysis patients : impact of genetics, inflammation and vitamin D 

    Molanaei, Hadi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-12-28)
    Chronic kidney disease (CKD) patients are at a high risk for drug adverse effects due to accumulation of drugs, which normally are excreted via the kidneys. It is believed that drugs that are metabolized by the liver are ...
  • Peptide and non-peptide biomarkers of mortality in patients with advanced chronic kidney disease 

    Sun, Jia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-23)
    Over the last decade, multiple studies have attempted to identify better risk prediction tools specific to the chronic kidney disease (CKD) population. In many cases, these studies have evaluated the use of various peptide ...
  • Cochlear implantation : experimental and clinical studies 

    Smeds, Henrik (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-18)
    Cochlear implantation makes hearing restoration possible in patients with severe to profound hearing loss. However, patients with residual hearing, where a cochlear implant may be combined with acoustic stimulation, and ...
  • Consequences of outsourcing referrals for radiological examinations 

    Tavakol Olofsson, Parvin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-14)
    Background: Demands for ever more effective healthcare and care accessibility for all patients continue to increase the workload in diagnostic radiology departments. Along with rapid developments in imaging technology which ...
  • Dialysis initiation and clinical outcomes in chronic kidney disease : role of education and biomarkers 

    Machowska, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-09)
    For patients with chronic kidney disease (CKD) who develop kidney failure, renal replacement therapy (RRT) with kidney transplantation is the best treatment option. But if this is not possible due to lack of organs or ...
  • Speech outcome in children born with cleft lip and palate treated with one-stage palate repair : aspects of function and environment 

    Nyberg, Jill (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-09)
    Introduction and aims: This project focused on speech outcomes at 5 and 10 years of age after two different surgical protocols and on peer perceptions of speech in children born with cleft palate. The aim was to gain ...
  • The evaluation, preoperative and operative aspects of abdominal wall reconstruction for giant ventral hernia 

    Clay, Leonard (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-10-19)
    BACKGROUND: The optimal method for surgical repair of giant ventral hernia remains to be determined. Different concepts for reinforcement have been used, which have decreased the risk for recurrence. However, the use of ...
  • Non invasive ventilation in people with cystic fibrosis 

    Rodriguez Hortal, Cecilia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-10-14)
    Background: Cystic fibrosis (CF) is the most common life shortening autosomal recessive inherited disease affecting Caucasian people. The two main clinical characteristics of CF are progressive pulmonary disease and ...
  • Innate immunity and cardiac structure in chronic kidney disease 

    Wallquist, Carin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-26)
    The inflammatory state of chronic kidney disease (CKD) leads to increased susceptibility to infections and cardiovascular complications. In this thesis we aimed to investigate development of inflammatory properties at ...
  • Towards heart rate variability tools in P-Health 

    Abtahi, Farhad (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-08)
    Heart rate variability (HRV) has received much attention lately, and several techniques for the analysis of HRV using time and frequency domains and non-linear methods have been developed. It has been shown that HRV can ...
  • Early obesity : family-based risk factors and treatment interventions 

    Ek, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-01)
    Background The high prevalence of preschool obesity is a global concern. In order to support families through obesity interventions, we need a better understanding of underlying family-based risk factors. Specifically, ...
  • Drug and disease effects on the human brain studied by functional MRI 

    Engström Nordin, Love (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-08-19)
    Background: With the advent of magnetic resonance imaging (MRI) technology, various functional MRI (fMRI) techniques have become available for non-invasive neuroscientific studies and clinical diagnostics, which have led ...
  • Cerebral microbleeds and cognitive impairment 

    Shams, Sara (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-08-12)
    Background: With increasingly ageing populations comes an increased prevalence of cognitive impairment and dementia. The pathophysiology behind dementia is still unknown, and there is no cure. Microscopic bleeds in the ...
  • Aspects of neoadjuvant therapy in the curative treatment of cancer in the esophagus or gastroesophageal junction 

    Klevebro, Fredrik (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-06-09)
    Malignant esophageal tumors are among the most severe cancers. Only about 30% of the patients are suitable for curative treatment at diagnosis. The treatment is extremely demanding and unfortunately has disappointing ...
  • Focal knee resurfacing : a translational study in sheep on the treatment of focal condylar cartilage lesions with metal implants 

    Martinez-Carranza, Nicolas (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-04-29)
    Background The translational process of introducing a new treatment concept in medicine from innovation to clinical application is a challenging endeavour that often involves animal experiments. Focal cartilage lesion ...
  • Markers of inflammation and cardiovascular disease in dialysis patients : variability and prognostic value 

    Snaedal, Sunna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-04-15)
    Patients with end-stage renal disease are burdened with a high cardiovascular morbidity and mortality. Inflammation is a common feature in these patients and strongly associates with cardiovascular complications and outcome. ...
  • Cardiopulmonary adaption to one-lung ventilation and neoadjuvant therapy during treatment of esophageal cancer 

    Lund, Mikael (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-04-13)
    Introduction: Esophagectomy is the main form of curative treatment for esophageal cancer and has a high morbidity rate. Neoadjuvant chemo- (CT) or chemoradiotherapy (CRT) is employed to increase long-term survival. To ...
  • Early cardiovascular risk markers and cardiac function in children with chronic kidney disease 

    Tranæus Lindblad, Ylva (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-04-08)
    Children with advanced chronic kidney disease (CKD) have an increased risk of premature death, foremost due to cardiovascular disease (CVD). The cardiovascular (CV) morbidity starts early in the disease process and renal ...

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