Avhandlingar / Theses
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Multidrug-resistant enterobacterales in Oman : molecular epidemiology and therapeutic insights
(Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2021-01-19)The spread of antibiotic resistance is a concerning issue causing limited treatment options for bacterial infections, particularly with Gram-negative bacteria. Surveillance and epidemiological studies help to determine ... -
Differentiation of renal oncocytoma from renal cell carcinoma by means of [99m]Tc-Sestamibi SPECT/CT
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-01-15)Purpose: An increasing body of literature indicates the beneficial role of [99m]Tc-Sestamibi SPECT/CT in the non-invasive differentiation of renal oncocytoma (RO) from renal cell carcinoma (RCC). This thesis presents a ... -
Augmented navigation
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-01-14)Spinal fixation procedures have the inherent risk of causing damage to vulnerable anatomical structures such as the spinal cord, nerve roots, and blood vessels. To prevent complications, several technological aids have ... -
Inflammatory arthritis and pregnancy
(Inst för medicin, Solna / Dept of Medicine, Solna, 2021-01-14)The aim of this thesis was to add to the existing knowledge of how inflammatory arthritis disease affects pregnancy outcomes. In particular, the aim was to describe and study the effects of a diagnosis of juvenile idiopathic ... -
Bacterial sensors and controllers based on organic bioelectronics
(Inst för neurovetenskap / Dept of Neuroscience, 2021-01-14)Bacterial infections and contaminations are worldwide problems, leading to morbidity and mortality, food waste and economic losses in a variety of industries. The situation is aggravated by the increased occurrence of ... -
Cost effectiveness of latent tuberculosis screening among asylum seekers in Stockholm
(Inst för global folkhälsa / Dept of Global Public Health, 2021-01-13)Introduction The burden of tuberculosis (TB) in Sweden is concentrated among migrants from high TB incidence countries. The incident cases in Sweden arise mainly through reactivation of a latent tuberculosis infection ... -
Crosstalk between environmental signals and 3d genome organization in the regulation of gene expression
(Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-01-12)The thesis explores the connection between environmental stimuli and gene expression regulated by the spatial changes in genome organization. In Paper I, by applying state of the art Circular Chromosome ... -
Platelet transfusions in hematological disorders
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2021-01-12)Platelets are important for clot formation and vascular integrity. Thrombocytopenic patients with hematological disorders are at risk of bleeding and platelet transfusions are important in supportive care and treatment of ... -
Acute myocardial infarction : early diagnosis and the prognostic value of ECG and echocardiography
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-12)Introduction Acute myocardial infarction (AMI) is a main cause of death. Despite vast improvements in management and treatment strategies over the past decades, morbidity and mortality after an AMI remains high. ... -
Prediction of psychological and physical morbidity after critical illness and intensive care unit stay
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2021-01-11)A large proportion of survivors of critical illness and intensive care unit stay suffer from post- intensive care syndrome (PICS), consisting of psychological, physical and cognitive problems. These problems can persist ... -
Evaluation of attention training after aquired brain injury : an occupational perspective
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-08)AIM: The aim of this thesis was to evaluate the effects of two different approaches of attention training, Attention Process Training (APT) and Activity-based Attention Training (ABAT) after ABI, on level of activity and ... -
Diabetes mellitus in patients with dementia : clinical care and pharmacological treatment
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-01-07)Diabetes mellitus (DM) and dementia are frequent chronic disorders in the older population, however their relationship is complex - while DM is an established risk factor for dementia, cognitive symptoms in dementia may ... -
Necrotizing enterocolitis : imaging and risk assessment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-01-07)Despite decades of research on necrotizing enterocolitis (NEC), no major finding has improved the mortality and morbidity of the disease or changed the clinical management. The exact pathogenesis remains unclear, but ... -
Enhanced recovery after surgery (ERAS) interventions and outcome from colorectal surgery
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-04)Although immense progress has been made in the fields of chemo- and radiotherapy during the last decades, surgery is still the ultimate cure for the majority of patients with colorectal cancer. Since colorectal cancer most ... -
Effect of shock wave therapy on longitudinal bone growth and growth plate cartilage
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-12-30)Aim: The overall aim of this thesis was to investigate the potential for radial shock wave treatment (rSWT) to regulate growth plate chondrogenesis and longitudinal bone growth. It was based on the hypothesis that the ... -
Assisted reproductive technologies for fertility preservation and fertility treatment in young women with cancer
(Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2020-12-30)Loss of fertility as a potential side effect of anti-neoplastic treatments may have a significant negative impact on the survivors’ quality of life. Assisted reproductive technologies (ART) have been adapted and further ... -
The orofacial cleft phenome
(Inst för odontologi / Dept of Dental Medicine, 2020-12-29)Introduction: The global average for prevalence in births with orofacial clefts is 9.92 per 10,000. Variability in prevalence could be as much as a seven-fold difference in different ethnicities. Precise phenotyping and ... -
New aspects on timing and graft morbidity in anterior cruciate ligament reconstruction
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2020-12-28)The aim of this thesis was to investigate the effect of different surgical techniques on knee function and outcomes after an anterior cruciate ligament (ACL) reconstruction (ACLR). In Study I, 70 patients with a ... -
Investigating adipose tissue turnover in humans using radiocarbon dating
(Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2020-12-28)Obesity, defined as an excessive accumulation of body fat, is considered one of the major health challenges facing the world today. Adipocyte and lipid turnover determine the number and the size of fat cells, respectively. ... -
Cell states along oligodendrocyte development and disease
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2020-12-23)The brain, one of the most complex organs in the body, where an immense diversity of cell states emerges from simple structure, where function arises from sets of regulatory principles and pattern persist where individual ...