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  • Experimental, mild blast-induced traumatic brain injury : focus on the monoamine and galanin systems 

    Kawa, Lizan (Inst för neurovetenskap / Dept of Neuroscience, 2017-02-14)
    Traumatic brain injury (TBI) is a common cause of mortality and morbidity among civilians and servicemen alike. The spectrum of TBIs encompasses mild to severe cases, with the predominate number of TBIs being mild (mTBI). ...
  • Molecular and epigenetic control of CNS tumour and progenitor cells 

    Gracias, Aileen (Inst för neurovetenskap / Dept of Neuroscience, 2017-02-09)
    Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances ...
  • Functional role of cerebrospinal fluid contacting cells in the spinal cord and hypothalamus 

    Jalalvand, Elham (Inst för neurovetenskap / Dept of Neuroscience, 2017-01-12)
    Cerebrospinal fluid-contacting (CSF-c) cells are found lining the walls of the central canal and the ventricles throughout the vertebrate phylum, but their function has remained elusive. The aim here was to investigate ...
  • Anatomical and functional characterization of serotonergic neurocircuitry 

    Pollak Dorocic, Iskra (Inst för neurovetenskap / Dept of Neuroscience, 2016-12-19)
    The serotonin system arises from a small collection of brainstem structures called the raphe nuclei and innervates much of the central nervous system. A relatively small number of serotonin neurons modulate a wide variety ...
  • Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study 

    Du, Kai (Inst för neurovetenskap / Dept of Neuroscience, 2016-11-25)
    Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to ...
  • Neuropeptides in the human postmortem brain : focus on galanin and its receptors in depression 

    Barde, Swapnali (Inst för neurovetenskap / Dept of Neuroscience, 2016-11-25)
    Neuropeptides represent the most diverse family of messenger molecules in the nervous system, which are co-expressed with key neurotransmitters in several brain regions. They modulate synaptic neurotransmission and have, ...
  • Molecular coding and physiological roles of excitatory neurons in motor control 

    Ribeiro Caldeira, Vanessa (Inst för neurovetenskap / Dept of Neuroscience, 2016-11-24)
    Locomotion is a complex motor action that provides humans and other animals with the ability to move through the environment. In vertebrate locomotion, supraspinal centers convey the initiating or terminating command signals ...
  • Att bedöma behov : utredningar av ungdomar som begått kriminella handlingar 

    Åström, Therese (Inst för neurovetenskap / Dept of Neuroscience, 2016-11-04)
    Syftet med föreliggande avhandling var att undersöka socialsekreterares utredningar och bedömningar av ungdomar som uppvisat kriminellt beteende, samt matchning mellan bedömda behov och rekommenderade behandlingsinsatser. ...
  • Multisensory mechanisms of body ownership and self-location 

    Guterstam, Arvid (Inst för neurovetenskap / Dept of Neuroscience, 2016-08-05)
    Having an accurate sense of the spatial boundaries of the body is a prerequisite for interacting with the environment and is thus essential for the survival of any organism with a central nervous system. Every second, ...
  • Neurotensin and cortical arousal : an in vitro study 

    Case, Lovisa (Inst för neurovetenskap / Dept of Neuroscience, 2016-05-31)
    The information processing associated with wakefulness occurs during what is commonly referred to as a cortical desynchronized state. In contrast, deep sleep is accompanied by slow, synchronized electrical activity, perhaps ...
  • Multifunctional biomimetic materials for corneal regeneration 

    Islam, Mohammad Mirazul (Inst för neurovetenskap / Dept of Neuroscience, 2016-05-25)
    The cornea is the outermost layer of the eye, which is responsible for transmitting 95% of the incident light to the retina for vision and provides 70% of the focusing power of the eye. Corneal disease is a primary cause ...
  • Where imagination meets sensation : mental imagery, perception and multisensory Integration 

    Berger, Christopher C. (Inst för neurovetenskap / Dept of Neuroscience, 2016-05-12)
    What happens if we imagine seeing something while we are listening to something? Will it change what we hear? What happens if we imagine hearing something while we are looking at something? Will it change what we see? ...
  • Tracking and predicting cognitive development using magnetic resonance imaging 

    Ullman, Henrik (Inst för neurovetenskap / Dept of Neuroscience, 2016-05-11)
    Neuroimaging of the developing brain has helped describing and quantifying many of the biological processes underlying cognitive development. The protracted development of higher order cognitive functions has allowed ...
  • Stem cell in-vitro strategies for the induction of sensory neurons for inner ear cell therapy 

    Ali, Rouknuddin Qasim (Inst för neurovetenskap / Dept of Neuroscience, 2016-01-29)
    The cochlea, a part of the auditory system, is a complex structure consisting of several different types of cells including hair cells and spiral ganglion neurons. In mammals, the regenerative potential of hair cells and ...
  • Neuronal mechanisms of feedback postural control 

    Hsu, Li-Ju (Inst för neurovetenskap / Dept of Neuroscience, 2015-12-17)
    Different species maintain a basic body posture due to the activity of the postural control system. An efficient control of the body orientation, as well as the body configuration, is important for standing and during ...
  • Conductance-based principles of neuronal firing and excitability 

    Zeberg, Hugo (Inst för neurovetenskap / Dept of Neuroscience, 2015-09-04)
    The brain is an electrical organ whose activity is determined by the flow of ions across cell membranes. As such, the conductances that control the ion flux is a key to our understanding of the nervous system. Neurons ...
  • Modelling depression in animals and the potential antidepressant effect of histaminergic modulation 

    Magara, Salvatore (Inst för neurovetenskap / Dept of Neuroscience, 2015-05-22)
    Depression is at the top position for "years lived with disability" (Smith, 2014). Its aetiology is unknown, but the pathogenesis implicates changes in glutamatergic neuronal plasticity. Glutamatergic plasticity likely ...
  • Generation and selection of motor behaviors neural circuits and endocannabinoid modulation 

    Song, Jianren (Inst för neurovetenskap / Dept of Neuroscience, 2015-05-13)
    The generation of basic motor behavior relies on the activation of spinal neuronal networks called central pattern generators (CPGs). Descending drive from higher brain areas activates the spinal CPG to generate motor ...
  • Oxidative stress in experimental traumatic brain injury 

    Günther, Mattias (Inst för neurovetenskap / Dept of Neuroscience, 2015-05-13)
    Traumatic brain injury (TBI) is a leading cause of death and disability among the young population in the industrialized world. The injury consists of immediate damage to the brain tissue, followed by a secondary response ...
  • Neurodegenerative diseases studied in human brain and rodent models 

    Gellhaar, Sandra (Inst för neurovetenskap / Dept of Neuroscience, 2015-02-19)
    Parkinson’s and Alzheimer’s disease are the two most common neurodegenerative diseases world-wide, but are still little understood. Papers in this thesis examine some of the possible pathogenic mechanisms with the help of ...

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