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  • Eradication of Helicobacter pylori and gastric and oesophageal cancer : a systematic review and meta-analysis of cohort studies 

    Doorakkers, Eva; Lagergren, Jesper; Engstrand, Lars; Brusselaers, Nele (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell BiologyInst för molekylär medicin och kirurgi / Dept of Molecular Medicine and SurgeryKing's College London, 2017-04-28)
    Background: Helicobacter pylori (H. pylori) is associated with an increased risk of gastric adenocarcinoma and gastric mucosa associated lymphoid tissue (MALT) lymphoma, and a seemingly decreased risk of oesophageal ...
  • Why oesophageal adenocarcinoma is occurring more frequently 

    Doorakkers, Eva; Brusselaers, Nele (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-04-28)
    The incidence of oesophageal adenocarcinoma has increased rapidly over the past decades in the Western world. The prognosis is poor with a mean 5-year survival rate of 19% in the Netherlands. Important risk ...
  • Parental antibiotics and childhood asthma : a population-based study 

    Örtqvist, A.K.; Lundholma, C.; Fang, F.; Fall, T.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-28)
    In this population-based study on antibiotic treatment before, during and after pregnancy, using paternal exposure as negative control, we confirm that associations between maternal antibiotic exposure and childhood asthma ...
  • Intratumoral lactate metabolism in Barrett’s esophagus and adenocarcinoma 

    Kauppila, Joonas; Huhta, Heikki; Helminen, Olli; Palomäki, Sami; Lehenkari, Petri; Saarnio, Juha; Karttunen, Tuomo (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-04-25)
    Background: Monocarboxylate transporters (MCTs) are cell membrane proteins which transport pyruvate, lactate and ketone bodies across the plasma membrane. MCTs are activated in various cancers, but their expression in ...
  • Extent of lymphadenectomy and prognosis after esophageal cancer surgery 

    Lagergren, Jesper; Mattsson, Fredrik; Zylstra, Janine; Chang, Fuju; Gossage, James; Mason, Robert; Lagergren, Pernilla; Davies, Andrew (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-04-24)
    IMPORTANCE: The prognostic role of the extent of lymphadenectomy during surgery for esophageal cancer is uncertain and requires clarification. OBJECTIVE: To clarify whether the number of removed lymph nodes influences ...
  • Weekday of oesophageal cancer surgery in relation to early postoperative outcomes in a nationwide Swedish cohort study 

    Lagergren, Jesper; Mattsson, Fredrik; Lagergren, Pernilla (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-04-24)
    Objectives: Later weekday of surgery for oesophageal cancer seems to increase 5-year mortality, but the mechanisms are unclear. We hypothesised that early postoperative reoperations and mortality might explain this ...
  • Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer 

    Kazemi, Mohammad Hossein (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2017-04-24)
    Tumor cells overcome anti-tumor responses in part through immunosuppressive mechanisms. There are several immune modulatory mechanisms. Among them, adenosine is an important factor which is generated by both cancer and ...
  • Risk of eating disorders in immigrant populations 

    Mustelin, L.; Hedman, A.; Thornton, L.M.; Kuja-Halkola, R.; Keski-Rahkonen, A.; Cantor-Graae, E.; Almqvist, C.; Lichtenstein, P.; Mortensen, P.B.; Böcker Pedersen, C.; Bulik, C.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Objective: The risk of certain psychiatric disorders is elevated among immigrants. To date, no population studies on immigrant health have addressed eating disorders. We examined whether risk of eating disorders in first- ...
  • The association between childhood relocations and subsequent risk of suicide attempt, psychiatric problems, and low academic achievement 

    Bramson, L.M.; Rickert, M.E.; Class, Q.A.; Sariaslan, A.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; D'Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Given the frequency with which families change residences, the effects of childhood relocations have gained increasing research attention. Many researchers have demonstrated that childhood relocations are ...
  • Depression or anxiety in adult twins is associated with asthma diagnosis but not with offspring asthma 

    Tedner, S.G.; Lundholm, C.; Olsson, H.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Asthma is common in both children and adults in the Western world, just like anxiety and depression. While some research has revealed that these diseases might share important environmental and pathophysiological ...
  • No association between macrolide treatment in infancy and later pyloric stenosis in Sweden 

    Ludvigsson, Jonas; Lundholm, Cecilia; Örtqvist, Anne K; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-30)
  • Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study 

    Falhammar, H.; Frisén, L.; Linden Hirschberg, A.; Norrby, C.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)
    CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. ...
  • Registers of the Swedish total population and their use in medical research 

    Ludvigsson, J.F.; Almqvist, C.; Edstedt Bonamy, A-K.; Ljung, R.; Michaëlsson, K.; Neovius, M.; Stephansson, O.; Ye, W. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)
    The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the ...
  • Parental cancer diagnosis and child mortality : a population-based cohort study in Sweden 

    Chen, R.; Sjölander, A.; Valdimarsdóttir, U.; Varnum, C.; Almqvist, C.; Ye, W.; Fall, K.; Czene, K.; Fang, F. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    OBJECTIVE: Cancer diagnosis is known to induce severe psychological stress for the diagnosed patients; however, how it affects the next-of-kin is less well documented. This study aimed to assess the impact ...
  • A Genetically informed study of the associations between maternal age at childbearing and adverse perinatal outcomes 

    Sujan, A.C.; Rickert, M.E.; Class, Q.A.; Coyne, C.A.; Lichtenstein, P.; Almqvist, C.; Larsson, H.; Sjölander, A.; Lahey, B.B.; van Hulle, C.; Waldman, I.; Öberg, A.S.; D’Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    We examined associations of maternal age at childbearing (MAC) with gestational age and fetal growth (i.e., birth weight adjusting for gestational age), using two genetically informed designs (cousin and ...
  • Association of labor induction with offspring risk of autism spectrum disorders 

    Öberg, A.S.; D’Onofrio, B.M.; Rickert, M.E.; Hernandez-Diaz, S.; Ecker, J.L.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; Bateman, B.T. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    IMPORTANCE: Induction of labor is a frequently performed obstetrical intervention. It would thus be of great concern if reported associations between labor induction and offspring risk of autism spectrum ...
  • Hypospadias as a novel feature in spinal bulbar muscle atrophy 

    Nordenvall, A.S.; Paucar, M.; Almqvist, C.; Nordenström, A.; Frisén, L.; Nordenskjöld, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene. The SBMA phenotype consists of slowly progressive neuromuscular ...
  • Individual maternal and child exposure to antibiotics in hospital : a national population-based validation study. 

    Almqvist, C.; Örtqvist, A.K.; Gong, T.; Wallas, A.; Ahlén, K.M.; Ye, W.; Lundholm, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Aim: Exposure to antibiotics in early life may affect future health. Most antibiotics are prescribed in outpatient care, but inpatient exposure is also important. We estimated how specific diagnoses in hospitals corresponded ...
  • Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency 

    Falhammar, H.; Frisén, L.; Norrby, C.; Linden Hirschberg, A.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ...
  • Similar familial risk in multiple sclerosis subgroups Introduction 

    Song, J.; Karrenbauer, V.; Manouchehrinia, A.; Almqvist, C.; Hillert, J.; Westerlind, H. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)

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