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  • Breast and prostate cancer : the impact of diagnosis and treatment on sick leave and work 

    Plym, Anna (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-12-17)
    Treatment for breast or prostate cancer can have negative consequences on working life. In addition to sick leave during treatment, women and men with breast or prostate cancer are at increased risk of permanent absence ...
  • Agreement between asthma questionnaire and health care register data 

    Hedman, Anna M; Gong, Tong; Lundholm, Cecilia; Dahlén, Elin; Ullemar, Vilhelmina; Brew, Bronwyn B; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)
    Purpose: Risk factors and consequences of asthma can be studied using validated questionnaires. The overall objective of this study was to assess the agreement of parental-reported asthma related questions regarding their ...
  • Allergen-specific IgE over time in women before, during and after pregnancy 

    Hedman, Anna M; Lundholm, Cecilia; Scheynius, Annika; Alm, Johan; Andolf, Annika; Pershagen, Göran; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)
    The trajectory of IgE levels before, during and after pregnancy in sensitized individuals is characterized by significant increase in specific IgE to birch allergens but not to other allergens after multiple testing. This ...
  • Bidirectional relationship between eating disorders and autoimmune diseases 

    Hedman, Anna; Breithaupt, Lauren; Hubel, Christopher; Thornton, Laura M; Tillander, Annika; Norring, Claes; Birgegård, Andreas; Larsson, Henrik; Ludvigsson, Jonas; Sävendahl, Lars; Almqvist, Catarina; Bulik, Cynthia M (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)
    Background: Immune system dysfunction may be associated with eating disorders, and associations could have implications for detection, risk assessment, and treatment of both autoimmune diseases and eating disorders. However, ...
  • Panorama of diseases associated with breast cancer 

    Yang, Haomin (Karolinska Institutet Universitetsbiblioteket / Karolinska Institutet University Library, 2018-11-16)
    Breast cancer is the most common cancer in women. Although the incidence of breast cancer has increased over time, so too has patient survival. Given these trends, the prevalence of breast cancer has steadily increased in ...
  • Survivorship in Hodgkin lymphoma : childbearing and treatment-related disease 

    Weibull, Caroline E. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-10-16)
    Cancer is often considered a disease with, historically, poor survival that affects middle-aged and elderly individuals. Hodgkin lymphoma (HL) is a lymphatic malignancy that affects both young and old individuals, with the ...
  • Severe psychological stress associated with a cancer diagnosis 

    Zhu, Jianwei (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-10-04)
    Receiving a cancer diagnosis leads to severe psychological distress. Previous studies have shown increased risk for various health consequences following a cancer diagnosis, including mental disorders, life-threatening ...
  • Diet, lifestyle and chronic kidney disease 

    Xu, Hong (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-09-18)
    Chronic kidney disease (CKD) is a rapidly growing public health problem, affecting 5-10% of the general population, and individuals with CKD have a substantially increased risk of morbi-mortality. Early detection and ...
  • Statistical models of breast cancer tumour progression for mammography screening data 

    Abrahamsson, Linda (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-09-17)
    In this thesis we propose a novel statistical natural history model and illustrate how it can be applied to epidemiological breast cancer screening data to increase knowledge about how breast cancers progress over time ...
  • Parkinson’s disease etiology : beyond the brain and late adulthood 

    Liu, Bojing (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-08-27)
    Despite much effort investigating the etiology of Parkinson’s disease (PD), the causes and the exact mechanisms underlying the disease remain elusive. Braak’s hypothesis suggests that PD pathology may start in the enteric ...
  • Genetic epidemiology of cardiometabolic biomarkers : twin studies in the genomic era 

    Chen, Xu (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-05-25)
    Following the Human Genome Project, many genomic approaches have been developed in genetic epidemiology to investigate the genetic influences on human complex traits. This thesis aims to answer four genetic epidemiological ...
  • Determinants of interval cancer and tumor size among breast cancer screening participants 

    Strand, Fredrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-05-15)
    Breast cancer is the most common cancer of women in Sweden and globally. In the more affluent countries, mammography screening has been in place for a few decades and has successfully reduced mortality. However, there ...
  • Vaccine safety, vaccine effectiveness and other determinants for successful immunisation programmes 

    Lamb, Favelle (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-05-11)
    The studies in this thesis examined several key determinants for successful uptake of vaccinations in the Nordic countries, with focus on vaccine safety and vaccine effectiveness. In study I, we investigated whether ...
  • Impact of infertility and assisted reproductive technology on cancer risk 

    Lundberg, Frida E. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-05-07)
    Ovarian stimulation drugs, in particular those used in assisted reproductive technology (ART) treatments for infertility, have been suspected to influence cancer risk. In addition, infertility per se may be a risk factor ...
  • Asthma, anxiety and depression in pregnancy : the impact on pregnancy, delivery and perinatal outcomes 

    Rejnö, Gustaf (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-04-27)
    Asthma and mood disorders such as anxiety or depression are associated with adverse pregnancy, delivery, and perinatal outcomes. There is an association between mood disorders and asthma and there may be common mechanisms ...
  • The role of sleep and shift work in dementia and cognitive aging : an epidemiological approach 

    Bokenberger, Kathleen (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-04-26)
    Dementia is a syndrome that afflicts older persons and is characterized by progressive deterioration in memory and other cognitive functions, behavior, and the ability to perform day-to-day activities. Older adults, and ...
  • A short story of the long telomere : evidence in aging epidemiology 

    Zhan, Yiqiang (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-04-04)
    Telomeres are the sequences of nucleotides at the end of chromosomes. Each time a cell divides, telomeres become shorter. The length of telomeres can be replenished by an enzyme, telomerase. Telomere shortening is ...
  • ADHD, epilepsy, and related childhood psychopathology : understanding shared genetic risk, developmental trajectories, and pharmacological treatment safety 

    Brikell, Isabell (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-03-29)
    Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder, affecting 5-7% of children and 2.5-5% of adults worldwide. The disorder is characterized by excessive and age-inappropriate symptoms ...
  • Outcome-dependent associations between short interpregnancy interval and offspring psychological and educational problems : a population-based quasi-experimental study 

    Class, Quetzal A; Rickert, Martin E.; Larsson, Henrik; Öberg, Anna S.; Sujan, Ayesha; Amlqvist, Catarina; Lichtenstein, Paul; D’Onofrio, Brian (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-03-21)
  • Flexible parametric models for cancer patient survival : loss in expectation of life and further developments 

    Bower, Hannah (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-03-01)
    Population-based cancer studies can contribute to a better understanding of cancer patient survival. The general aim of this thesis was to develop and apply statistical methods for population-based cancer studies to ...

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