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  • Parental antibiotics and childhood asthma : a population-based study 

    Örtqvist, A.K.; Lundholma, C.; Fang, F.; Fall, T.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-28)
    In this population-based study on antibiotic treatment before, during and after pregnancy, using paternal exposure as negative control, we confirm that associations between maternal antibiotic exposure and childhood asthma ...
  • Risk of eating disorders in immigrant populations 

    Mustelin, L.; Hedman, A.; Thornton, L.M.; Kuja-Halkola, R.; Keski-Rahkonen, A.; Cantor-Graae, E.; Almqvist, C.; Lichtenstein, P.; Mortensen, P.B.; Böcker Pedersen, C.; Bulik, C.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Objective: The risk of certain psychiatric disorders is elevated among immigrants. To date, no population studies on immigrant health have addressed eating disorders. We examined whether risk of eating disorders in first- ...
  • The association between childhood relocations and subsequent risk of suicide attempt, psychiatric problems, and low academic achievement 

    Bramson, L.M.; Rickert, M.E.; Class, Q.A.; Sariaslan, A.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; D'Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Given the frequency with which families change residences, the effects of childhood relocations have gained increasing research attention. Many researchers have demonstrated that childhood relocations are ...
  • Depression or anxiety in adult twins is associated with asthma diagnosis but not with offspring asthma 

    Tedner, S.G.; Lundholm, C.; Olsson, H.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Asthma is common in both children and adults in the Western world, just like anxiety and depression. While some research has revealed that these diseases might share important environmental and pathophysiological ...
  • Stress, depression, and other psychiatric disorders : an epidemiological approach to studying the causes and consequences for in vitro fertilization outcome and polycystic ovary syndrome 

    Cesta, Carolyn E. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-20)
    Reproductive epidemiology, psychiatric epidemiology, and pharmacoepidemiology come together in this thesis which is comprised of four studies and divided into two parts. Part 1 examines the impact of stress and ...
  • Statistical methods for twin and sibling designs 

    Zetterqvist, Johan (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-20)
    Twin and sibling studies are valuable in that they allow adjustment for potential confounding factors that are impossible or hard to measure. By measuring associations ‘within-cluster’ it is possible to adjust for many ...
  • Metabolic disorders in the etiology of amyotrophic lateral sclerosis : an epidemiological approach 

    Mariosa, Daniela (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-13)
    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a loss of motor neurons in the brain and spinal cord, leading to progressive muscle weakness in multiple regions of the body. No ...
  • Parental cancer and children’s well-being : understanding the potential role of psychological stress 

    Chen, Ruoqing (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-07)
    Early life stress has a major influence on one’s health through the life course. During childhood, early experience may not only affect the normal brain development, but also influence the susceptibility to mental and ...
  • No association between macrolide treatment in infancy and later pyloric stenosis in Sweden 

    Ludvigsson, Jonas; Lundholm, Cecilia; Örtqvist, Anne K; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-30)
  • Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study 

    Falhammar, H.; Frisén, L.; Linden Hirschberg, A.; Norrby, C.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)
    CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. ...
  • Registers of the Swedish total population and their use in medical research 

    Ludvigsson, J.F.; Almqvist, C.; Edstedt Bonamy, A-K.; Ljung, R.; Michaëlsson, K.; Neovius, M.; Stephansson, O.; Ye, W. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)
    The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the ...
  • Parental cancer diagnosis and child mortality : a population-based cohort study in Sweden 

    Chen, R.; Sjölander, A.; Valdimarsdóttir, U.; Varnum, C.; Almqvist, C.; Ye, W.; Fall, K.; Czene, K.; Fang, F. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    OBJECTIVE: Cancer diagnosis is known to induce severe psychological stress for the diagnosed patients; however, how it affects the next-of-kin is less well documented. This study aimed to assess the impact ...
  • A Genetically informed study of the associations between maternal age at childbearing and adverse perinatal outcomes 

    Sujan, A.C.; Rickert, M.E.; Class, Q.A.; Coyne, C.A.; Lichtenstein, P.; Almqvist, C.; Larsson, H.; Sjölander, A.; Lahey, B.B.; van Hulle, C.; Waldman, I.; Öberg, A.S.; D’Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    We examined associations of maternal age at childbearing (MAC) with gestational age and fetal growth (i.e., birth weight adjusting for gestational age), using two genetically informed designs (cousin and ...
  • Association of labor induction with offspring risk of autism spectrum disorders 

    Öberg, A.S.; D’Onofrio, B.M.; Rickert, M.E.; Hernandez-Diaz, S.; Ecker, J.L.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; Bateman, B.T. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    IMPORTANCE: Induction of labor is a frequently performed obstetrical intervention. It would thus be of great concern if reported associations between labor induction and offspring risk of autism spectrum ...
  • Hypospadias as a novel feature in spinal bulbar muscle atrophy 

    Nordenvall, A.S.; Paucar, M.; Almqvist, C.; Nordenström, A.; Frisén, L.; Nordenskjöld, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene. The SBMA phenotype consists of slowly progressive neuromuscular ...
  • Can Parkinson’s disease be prevented? : epidemiological evidence on lifestyle factors 

    Yang, Fei (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-24)
    The etiology of Parkinson’s disease (PD) is largely unknown, but epidemiological studies have provided robust evidence that environmental factors have a central role in PD pathogenesis and progression. The studies included ...
  • Individual maternal and child exposure to antibiotics in hospital : a national population-based validation study. 

    Almqvist, C.; Örtqvist, A.K.; Gong, T.; Wallas, A.; Ahlén, K.M.; Ye, W.; Lundholm, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Aim: Exposure to antibiotics in early life may affect future health. Most antibiotics are prescribed in outpatient care, but inpatient exposure is also important. We estimated how specific diagnoses in hospitals corresponded ...
  • Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency 

    Falhammar, H.; Frisén, L.; Norrby, C.; Linden Hirschberg, A.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ...
  • Similar familial risk in multiple sclerosis subgroups Introduction 

    Song, J.; Karrenbauer, V.; Manouchehrinia, A.; Almqvist, C.; Hillert, J.; Westerlind, H. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
  • Exposure to air pollution from traffic and neurodevelopmental disorders in Swedish twins 

    Gong, T.; Almqvist, C.; Bolte, S.; Lichtenstein, P.; Anckarsater, H.; Lind, T.; Lundholm, C.; Pershagen, G. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-17)
    Background: Recent studies have reported associations between air pollution exposure and neurodevelopmental disorders in children but the role of pre- and postnatal exposure has not been elucidated. Aim: We aimed ...

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