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  • Mode of obstetrical delivery and type 1 diabetes : a sibling design study 

    Khashan, Ali S; Kenny, Louise C; Lundholm, Ceciclia; Kearney, Patricia M; Gong, Tong; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)
    OBJECTIVES: We investigated the association between cesarean section (CS) and type 1 diabetes (T1D), and if the association remains after accounting for familial confounding by using a sibling-control design. ...
  • Are carriers of CYP21A2 mutations less vulnerable to psychological stress? A population-based national cohort study 

    Nordenström, A.; Butwicka, A.; Linden Hirschberg, A.; Almqvist, C.; Nordenskjöld, A.; Falhammar, H.; Frisen, L. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)
    Background Congenital adrenal hyperplasia (CAH) is one of the most common monogenic autosomal recessive disorders with an incidence of one in 15 000. About one in 70 individuals in the general population are carriers ...
  • The influence of childhood asthma on puberty and height in Swedish adolescents 

    Protudjer P., J.L.; Lundholm, C.; Bergström, A.; Kull, I.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)
    BACKGROUND: Evidence relating to the effect of asthma on puberty or height is inconclusive. We aimed to examine whether the exposure of childhood asthma, including timing and phenotypes, and inhaled corticosteroid ...
  • Asthma and height in twins : a cohort and within-pair analyses study. 

    Protudjer, Jennifer; Lundholm, Cecilia; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)
    In singletons, asthma may be associated with shorter height and delayed growth during adolescence. Yet, these studies do not account for heritability of asthma, puberty/menarche, and height. We aimed to study ...
  • Paternal age at childbirth and eating disorders in offspring 

    Javaras, K.N.; Rickert, M.E.; Thornton, L.M.; Peat, C.M.; Baker, J.H.; Birgegard, A.; Norring, C.; Landen, M.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; Bulik, C.M.; D'Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-05-24)
    Background. Advanced paternal age at childbirth is associated with psychiatric disorders in offspring, including schizophrenia, bipolar disorder and autism. However, few studies have investigated paternal age’s relationship ...
  • The role of psychological stress in cervical and prostate carcinogenesis 

    Lu, Donghao (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-05-23)
    Psychological stress is common in everyday life, and has been well recognized as one of the major contributors to many mental and physical illnesses, such as mental disorders and cardiovascular diseases. The association ...
  • Gestational age and birth weight and the risk of childhood type 1 diabetes : a population-based cohort and sibling design study 

    Khashan, Ali S; Kenny, Louise C; Lundholm, Cecilia; Kearny, Patricia M; Gong, Tong; McNamee, Roseanne; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-05-10)
    Objectives: We investigated the effects of gestational age, birthweight, small for gestational age (SGA) and large for gestational age (LGA) on childhood type 1 diabetes. Methods: We conducted a population-based ...
  • Efficient design and analysis of extended case-control studies 

    Delcoigne, Bénédicte (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-05-10)
    The nested case-control design is widely used in epidemiology for its efficiency, as it combines the advantages of both cohort and case-control designs. This design is an extension of the matched case-control design, where ...
  • Parental antibiotics and childhood asthma : a population-based study 

    Örtqvist, A.K.; Lundholma, C.; Fang, F.; Fall, T.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-28)
    In this population-based study on antibiotic treatment before, during and after pregnancy, using paternal exposure as negative control, we confirm that associations between maternal antibiotic exposure and childhood asthma ...
  • Risk of eating disorders in immigrant populations 

    Mustelin, L.; Hedman, A.; Thornton, L.M.; Kuja-Halkola, R.; Keski-Rahkonen, A.; Cantor-Graae, E.; Almqvist, C.; Lichtenstein, P.; Mortensen, P.B.; Böcker Pedersen, C.; Bulik, C.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Objective: The risk of certain psychiatric disorders is elevated among immigrants. To date, no population studies on immigrant health have addressed eating disorders. We examined whether risk of eating disorders in first- ...
  • The association between childhood relocations and subsequent risk of suicide attempt, psychiatric problems, and low academic achievement 

    Bramson, L.M.; Rickert, M.E.; Class, Q.A.; Sariaslan, A.; Almqvist, C.; Larsson, H.; Lichtenstein, P.; D'Onofrio, B.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Given the frequency with which families change residences, the effects of childhood relocations have gained increasing research attention. Many researchers have demonstrated that childhood relocations are ...
  • Depression or anxiety in adult twins is associated with asthma diagnosis but not with offspring asthma 

    Tedner, S.G.; Lundholm, C.; Olsson, H.; Almqvist, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-24)
    Background: Asthma is common in both children and adults in the Western world, just like anxiety and depression. While some research has revealed that these diseases might share important environmental and pathophysiological ...
  • Stress, depression, and other psychiatric disorders : an epidemiological approach to studying the causes and consequences for in vitro fertilization outcome and polycystic ovary syndrome 

    Cesta, Carolyn E. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-20)
    Reproductive epidemiology, psychiatric epidemiology, and pharmacoepidemiology come together in this thesis which is comprised of four studies and divided into two parts. Part 1 examines the impact of stress and ...
  • Statistical methods for twin and sibling designs 

    Zetterqvist, Johan (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-20)
    Twin and sibling studies are valuable in that they allow adjustment for potential confounding factors that are impossible or hard to measure. By measuring associations ‘within-cluster’ it is possible to adjust for many ...
  • Metabolic disorders in the etiology of amyotrophic lateral sclerosis : an epidemiological approach 

    Mariosa, Daniela (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-13)
    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a loss of motor neurons in the brain and spinal cord, leading to progressive muscle weakness in multiple regions of the body. No ...
  • Parental cancer and children’s well-being : understanding the potential role of psychological stress 

    Chen, Ruoqing (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-04-07)
    Early life stress has a major influence on one’s health through the life course. During childhood, early experience may not only affect the normal brain development, but also influence the susceptibility to mental and ...
  • No association between macrolide treatment in infancy and later pyloric stenosis in Sweden 

    Ludvigsson, Jonas; Lundholm, Cecilia; Örtqvist, Anne K; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-30)
  • Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study 

    Falhammar, H.; Frisén, L.; Linden Hirschberg, A.; Norrby, C.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)
    CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. ...
  • Registers of the Swedish total population and their use in medical research 

    Ludvigsson, J.F.; Almqvist, C.; Edstedt Bonamy, A-K.; Ljung, R.; Michaëlsson, K.; Neovius, M.; Stephansson, O.; Ye, W. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)
    The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the ...
  • Parental cancer diagnosis and child mortality : a population-based cohort study in Sweden 

    Chen, R.; Sjölander, A.; Valdimarsdóttir, U.; Varnum, C.; Almqvist, C.; Ye, W.; Fall, K.; Czene, K.; Fang, F. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)
    OBJECTIVE: Cancer diagnosis is known to induce severe psychological stress for the diagnosed patients; however, how it affects the next-of-kin is less well documented. This study aimed to assess the impact ...

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