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  • In vitro models aiming for fertility preservation 

    Albalushi, Halima (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-10-11)
    Fertility preservation is considered a great hope to people suffering from infertility as a consequence of developmental or genetic cause, a disease itself or its treatments sequelae. In vitro models are fundamental to ...
  • Cardiopulmonary function, quality of life and effects of exercise in children and adolescents with Fontan circulation 

    Rylander Hedlund, Eva (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-10-03)
    Background Survival of children and adolescents with Fontan circulation has increased over the last decades, and today a large majority survive to adult age. There is increasing concern regarding these children’s impaired ...
  • Von Willebrand disease in women : heavy menstrual bleeding and obstetrical bleeding 

    Govorov, Igor (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-09-25)
    Von Willebrand disease is the most common inherited bleeding disorder worldwide with a prevalence, reaching 1% of general population. vWD is equally distributed between genders. However, vWD-affected females experience ...
  • Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight 

    Rakow, Alexander (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-17)
    Prematurity affects more than 10% of infants worldwide and is the main reason for neonatal mortality. Improvements in neonatal care have led to higher survival rates into adulthood. Adverse events during organogenesis ...
  • Optic nerve hypoplasia in children - prevalence, associated disorders and genetic causes 

    Dahl, Sara (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-10)
    Optic nerve hypoplasia (ONH) is a congenital ocular malformation with a thin optic nerve in one or both eyes. ONH has been associated with neurodevelopmental disorders and pituitary dysfunction, but the prevalence of ...
  • Novel culture systems to model testicular function and organization 

    Alves Lopes, João Pedro (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-02)
    In vitro systems to model the testicular microenvironment are required to study physiology and pathology of the testis, the gonadotoxic effect of environmental and pharmaceutical chemicals, as well as to explore the ...
  • Psychological aspects in differences/disorders of sex development 

    Strandqvist, Anna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-07-24)
    Background Sex differentiation depends on a complex set of molecular events. These are at one point initiated by SRY gene expression and involve gene transcription, which in turn can be affected by the prescence ...
  • Extremely preterm birth : brain imaging and outcome at early school-age 

    Bolk, Jenny (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-05-09)
    There has been a dramatic increase in the survival of extremely preterm children over the last decades, and the awareness of the consequences of extremely preterm birth on the developing brain is increasing. This thesis ...
  • Late effects and health-related outcomes after allogeneic hematopoietic stem cell transplantation in childhood 

    Wilhelmsson, Mari (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-27)
    Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established treatment for many acquired or congenital disorders of the hematopoietic system. For some patients it may be the only curative option. Most ...
  • Local anaesthesia in term- and preterm infants 

    Anell Olofsson, Marie (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-24)
    Background Local anaesthesia is known to be a safe and effective method for postoperative pain manage- ment in adults and children. This convenient method is however rarely used in term and preterm infants, despite its ...
  • Epidemiologic studies on acute appendicitis in children 

    Almström, Markus (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-12)
    Acute appendicitis is the most common surgical emergency in children. A considerable effort has been made to develop and improve treatment and outcomes. A PubMed search yields over 20 000 publications on appendicitis. ...
  • Prevention of cervical cancer in countries with high and low incidence of the disease 

    Alder, Susanna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-11)
    Cervical cancer is to a large extent a preventable disease, through prophylactic human papillomavirus (HPV) vaccination and cervical cancer screening. Still, it is the second most common cancer among women in Argentina, ...
  • Long-term follow-up in children born with congenital diaphragmatic hernia 

    Öst, Elin (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-03-28)
    Congenital diaphragmatic hernia (CDH) is a developmental defect which occurs in approximately 1 per 3000 births. The incomplete development of the diaphragm early in gestation allows abdominal viscera to herniate into ...
  • Ontogeny of perception of maternal and nosocomial stimuli in infants 

    Frie, Jakob (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-02-27)
    Preterm born infants in neonatal units experience unusual sensory inputs that can shape and nurture their developing brains differently from full-term healthy newborn infants. To improve the care of preterm infants and ...
  • Treatment aspects, prognostic factors and outcome measures of lymphatic malformations 

    Ghaffarpour, Nader (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-02-23)
    Lymphatic malformations (LMs) are structural defects in the lymphatic vessels. LMs are histologically benign lesions, however, due to localization, size and unexpected swelling, they may cause serious complications that ...
  • Novel therapeutic targets in pediatric neural tumors 

    Milosevic, Jelena (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-02-16)
    The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. The ...
  • Transition from child healthcare to adult healthcare for adolescents with congenital heart disease 

    Burström, Åsa (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-02-09)
    The life-prospects for adolescents with congenital heart disease (CHD) have improved, and today more than 90% survive to adulthood and need to continue their care into adulthood. During adolescence, the adolescents needs ...
  • Novel therapy for neuroblastoma : focus on prostaglandin E2 and microsomal prostaglandin E synthases-1 

    Kock, Anna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-11-17)
    Cancer is a major public health problem and to date cancer is one of the leading causes of death worldwide. Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system. Neuroblastoma is one of the most ...
  • The breathing brainstem : development of inspiration 

    Forsberg, David (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-11-16)
    Breathing is essential for life, and yet we do not fully understand the mechanisms that control it. The main central pattern generators for respiration include the inspiratory generating region called the preBötzinger ...
  • Ladnaan : evaluation of a culturally tailored parenting support program to Somali-born parents 

    Osman, Fatumo (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-11-15)
    Background: Research shows that immigrant families encounter different complexities and challenges in a new host country, such as acculturation, isolation and lack of social support. These challenges have been shown to ...

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