• A neuroimaging perspective on regulation of emotion, reward, and attention 

  Bayard, Frida (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-04-22)

  Emotional symptoms and non-emotional symptoms such as inattention often co-occur. Each of these symptom domains covers symptoms that are distributed along a continuum across the population; from non-clinical levels to ...

• Advancing antiviral strategies against emerging RNA viruses by phenotypic drug discovery 

  Tampere, Marianna (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-04-21)

  Pathogenic RNA viruses can emerge from unexpected sources at unexpected times and cause severe disease in humans, as exemplified by the ongoing coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory ...

• The molecular basis of the development and diversity of proprioceptive neurons : a story of surviving and thriving 

  Wu, Haohao (Inst för neurovetenskap / Dept of Neuroscience, 2021-04-21)

  Proprioception, also known as the sixth sense, describes the sensation of our body position and movement. Its proper function is essential for our daily activities from coarse movements, e.g. locomotion, to precise movements, ...

• Traditional Chinese exercise in a contextually adapted cardiac rehabilitation program for chronic heart failure 

  Chen, Xiankun (Inst för global folkhälsa / Dept of Global Public Health, 2021-04-20)

  Background: Exercise-based cardiac rehabilitation (EBCR) is a therapy which benefits patients with chronic heart failure (CHF). The delivery of EBCR should adopt an evidencebased approach, as well as be culturally ...

• Thrombotic and cardiac disease in the antiphospholipid syndrome 

  Grosso, Giorgia (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-04-16)

  The antiphospholipid syndrome (APS) is a highly heterogeneous disease that presents with obstetric complications and/or thromboembolic events that can hit any side of the vascular tree in an unpredictable way. The common ...

• Methods development for the investigation of the mammalian genome radial architecture : the quantitative side 

  Girelli, Gabriele (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2021-04-16)

  The nucleus of mammalian cells cradles the genome, an ensemble of nucleic acid macromolecular polymers that store information in a physical form. For a cell to perform life-sustaining processes, reading and utilizing the ...

• Long-term aspects of stroke : survival, health-related quality of life and costs 

  Rudberg, Ann-Sofie (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-04-15)

  Stroke, a disease that affects millions of people globally every year, is an emergency situation requiring fast and immediate action in hospital. Acute stroke treatments have rapidly improved and been developed over the ...

• Complications due to acute rhinosinusitis in children 

  Hultman Dennison, Sofia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-04-15)

  Background There is a lack of population-based studies of complications to acute rhinosinusitis in children. Previous studies have demonstrated a possible effect of the conjugate pneumococcal vaccine (PCV) on hospital ...

• Dösnack : metoder och verktyg för samtal om döende, död och framtida vård i livets slutskede 

  Eneslätt, Malin (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2021-04-15)

  Introduction: Advance care planning has been described as a process of reflection and discussion about values and preferences for future end-of-life care. In Sweden, advance care planning is rarely systematically practiced ...

• Insulin resistance in children and adolescents : mechanisms and clinical effects 

  Ek, Anna Erika (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-04-15)

  Background: Insulin resistance is a condition in which insulin does not achieve appropriate response in different target tissues, it is associated with obesity and one of the main culprits in the development of type 2 ...

• In vitro and in vivo studies of Bruton tyrosine kinase (BTK) mutations & inhibition 

  Estupiñán Velásquez, Hernando Yesid (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2021-04-14)

  Bruton tyrosine kinase (BTK) is a non-receptor protein kinase that belongs to the TEC family kinases. It plays an important role in the B-cell receptor signaling pathway (BCR) and its pharmacological inhibition has been ...

• Global policy to local implementation : experiences from active tuberculosis case-finding in high-burden countries 

  Biermann, Olivia (Inst för global folkhälsa / Dept of Global Public Health, 2021-04-14)

  Background: Tuberculosis (TB) is one of the world’s leading infectious killers. Every year, an estimated 10 million people fall ill with the disease, of whom 2.9 million people are never diagnosed and treated. Thirty ...

• Feasibility of type 2 diabetes prevention : processes for detection, self-management and support in socioeconomically disadvantaged areas 

  Timm, Linda (Inst för global folkhälsa / Dept of Global Public Health, 2021-04-14)

  Background: Type 2 diabetes (T2D) is on the rise globally, affecting disadvantaged populations to a higher extent. Both T2D and prediabetes are often undiagnosed. Early detection of T2D and prediabetes is of importance ...

• Systems biology of mitochondrial dysfunction 

  Schober, Florian A. (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2021-04-12)

  The human body consumes vast amounts of metabolites that are transformed into one another, modified to useful building blocks and broken down to harvest their energy. Mitochondria are at the core of this metabolic turnover ...

• Prostate cancer : population-based screening and markers for long-term clinical outcome 

  Lundgren, Per-Olof (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-04-12)

  In 1988 and 1989 a large screening study for prostate cancer was launched in Stockholm, Sweden. At the time approximately 27 000 men between 55 and 70 years of age resided within a defined area of southern Stockholm. 2400 ...

• Improving endometrial carcinoma diagnostics 

  Nastic, Denis (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-04-08)

  Endometrial carcinoma is the most common gynecological malignancy and greatly affects global disease burden. Despite it being among the most common cancers it is relatively understudied and until recently poorly understood. ...

• Epiphora : impact on vision, outcome of lacrimal surgery and investigations with ultra-high-frequency ultrasound 

  Bohman, Elin (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-04-08)

  Epiphora is a common condition that often receives little attention. Excessive tear production creates an irregular and ever-changing ocular surface, affecting refraction and reducing vision. However, in a standard test ...

• Regulation of G2 phase and long-term consequences of DNA damage 

  Middleton, Anna Won (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2021-04-08)

  Cell proliferation requires the accurate replication of DNA and equal segregation of replicated genes, important for maintaining the integrity of newly formed cells. At the centre of this process is a series of coordinated ...

• Cell and organoid models to develop new antivirals and diagnostic methods for emerging viruses 

  Pettke, Aleksandra (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-04-08)

  The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is only the latest reminder of the urgent need for new antiviral strategies and diagnostic tools to improve preparedness for ...

• Spatial regulation of membrane receptor signaling using DNA origami 

  Fang, Trixy (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2021-04-07)

  Juxtracrine signaling between apposing membrane receptors and ligands is an important class of intercellular communication. Much focus has been directed towards studying the biochemical interactions between receptors and ...

View more