• Targeting cell envelope synthesis of Streptococcus pneumoniae and microfluidic diagnostic tool development 

  Reithuber, Elisabeth (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2021-01-25)

  Evolving antibiotic resistance warrants the development of new therapeutic and diagnostic approaches as part of the strategies to secure future antibacterial therapies and preserve the compounds currently available. Work ...

• Improved heart failure care organization including studies of diagnosis, risk prediction and biomarkers in heart failure with preserved ejection fraction 

  Matan, Dmitri (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-22)

  Background: Heart failure (HF) is a prevalent condition with low quality of life, high morbidity and mortality, and high societal costs. HF can be divided according to left ventricular ejection fraction (EF) into HF with ...

• In vivo and in vitro studies of the serotonin 1B receptor in relation to major depressive disorder and treatment with ketamine 

  Veldman, Emma (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-01-22)

  Despite the large implications of Major Depressive Disorder (MDD) on disease burden worldwide, current treatment options are suboptimal and a third of patients suffering from this disease do not respond to ...

• Multimodal neuroimaging of pain and inflammation in the central nervous system in patients with Fibromyalgia and Rheumatoid Arthritis 

  Sandström, Angelica (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-01-22)

  The prevalence of concomitant fibromyalgia (FM) is puzzlingly high among rheumatoid arthritis (RA) patients and a contemporary challenge is to resolve why some RA patients continue to report pain despite adequate treatment ...

• Multidrug-resistant enterobacterales in Oman : molecular epidemiology and therapeutic insights 

  Al-Farsi, Hissa (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2021-01-19)

  The spread of antibiotic resistance is a concerning issue causing limited treatment options for bacterial infections, particularly with Gram-negative bacteria. Surveillance and epidemiological studies help to determine ...

• Differentiation of renal oncocytoma from renal cell carcinoma by means of [99m]Tc-Sestamibi SPECT/CT 

  Tzortzakakis, Antonios (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-01-15)

  Purpose: An increasing body of literature indicates the beneficial role of [99m]Tc-Sestamibi SPECT/CT in the non-invasive differentiation of renal oncocytoma (RO) from renal cell carcinoma (RCC). This thesis presents a ...

• Augmented navigation 

  Burström, Gustav (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-01-14)

  Spinal fixation procedures have the inherent risk of causing damage to vulnerable anatomical structures such as the spinal cord, nerve roots, and blood vessels. To prevent complications, several technological aids have ...

• Inflammatory arthritis and pregnancy 

  Remaeus, Katarina (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-01-14)

  The aim of this thesis was to add to the existing knowledge of how inflammatory arthritis disease affects pregnancy outcomes. In particular, the aim was to describe and study the effects of a diagnosis of juvenile idiopathic ...

• Bacterial sensors and controllers based on organic bioelectronics 

  Butina, Karen (Inst för neurovetenskap / Dept of Neuroscience, 2021-01-14)

  Bacterial infections and contaminations are worldwide problems, leading to morbidity and mortality, food waste and economic losses in a variety of industries. The situation is aggravated by the increased occurrence of ...

• Cost effectiveness of latent tuberculosis screening among asylum seekers in Stockholm 

  Shedrawy, Jad (Inst för global folkhälsa / Dept of Global Public Health, 2021-01-13)

  Introduction The burden of tuberculosis (TB) in Sweden is concentrated among migrants from high TB incidence countries. The incident cases in Sweden arise mainly through reactivation of a latent tuberculosis infection ...

• Crosstalk between environmental signals and 3d genome organization in the regulation of gene expression 

  Lewandowska Ronnegren, Anna (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-01-12)

  The thesis explores the connection between environmental stimuli and gene expression regulated by the spatial changes in genome organization. In Paper I, by applying state of the art Circular Chromosome ...

• Platelet transfusions in hematological disorders 

  Karlström, Cecilia (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2021-01-12)

  Platelets are important for clot formation and vascular integrity. Thrombocytopenic patients with hematological disorders are at risk of bleeding and platelet transfusions are important in supportive care and treatment of ...

• Acute myocardial infarction : early diagnosis and the prognostic value of ECG and echocardiography 

  Muhrbeck, Josephine (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-12)

  Introduction Acute myocardial infarction (AMI) is a main cause of death. Despite vast improvements in management and treatment strategies over the past decades, morbidity and mortality after an AMI remains high. ...

• Prediction of psychological and physical morbidity after critical illness and intensive care unit stay 

  Milton, Anna (Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2021-01-11)

  A large proportion of survivors of critical illness and intensive care unit stay suffer from post- intensive care syndrome (PICS), consisting of psychological, physical and cognitive problems. These problems can persist ...

• Evaluation of attention training after aquired brain injury : an occupational perspective 

  Landahl, Kristina Sargénius (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-08)

  AIM: The aim of this thesis was to evaluate the effects of two different approaches of attention training, Attention Process Training (APT) and Activity-based Attention Training (ABAT) after ABI, on level of activity and ...

• Diabetes mellitus in patients with dementia : clinical care and pharmacological treatment 

  Sečník, Juraj (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-01-07)

  Diabetes mellitus (DM) and dementia are frequent chronic disorders in the older population, however their relationship is complex - while DM is an established risk factor for dementia, cognitive symptoms in dementia may ...

• Necrotizing enterocolitis : imaging and risk assessment 

  Palleri, Elena (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-01-07)

  Despite decades of research on necrotizing enterocolitis (NEC), no major finding has improved the mortality and morbidity of the disease or changed the clinical management. The exact pathogenesis remains unclear, but ...

• Enhanced recovery after surgery (ERAS) interventions and outcome from colorectal surgery 

  Asklid, Daniel (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2021-01-04)

  Although immense progress has been made in the fields of chemo- and radiotherapy during the last decades, surgery is still the ultimate cure for the majority of patients with colorectal cancer. Since colorectal cancer most ...

• Effect of shock wave therapy on longitudinal bone growth and growth plate cartilage 

  Ramesh, Sowmya (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-12-30)

  Aim: The overall aim of this thesis was to investigate the potential for radial shock wave treatment (rSWT) to regulate growth plate chondrogenesis and longitudinal bone growth. It was based on the hypothesis that the ...

• Assisted reproductive technologies for fertility preservation and fertility treatment in young women with cancer 

  Marklund, Anna (Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2020-12-30)

  Loss of fertility as a potential side effect of anti-neoplastic treatments may have a significant negative impact on the survivors’ quality of life. Assisted reproductive technologies (ART) have been adapted and further ...

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