Now showing items 1-20 of 7291

  • Pediatric obstructive sleep apnea - evaluation of questionnaire and surgical treatment 

    Borgström, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-23)
    Obstructive sleep apnea (OSA) is a major pediatric health problem and is associated with potentially severe consequences if left untreated. Diagnosing OSA in children can be challenging since the clinical symptoms are ...
  • Transfusion in critically ill patients: short- and long-term outcomes 

    Halmin, Märit (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-02-23)
    A blood transfusion is a common treatment for a range of conditions. Over 112 million blood transfusions are administered each year worldwide and many patients are thereby exposed to the possible risks associated with the ...
  • Vårdskador vid omvårdnad : en studie av patienters, anhörigas och vårdgivares anmälningar 

    Andersson, Åsa (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-23)
    Background: Patient safety has, over the last decades, been increasingly established as an important global issue. Patient safety is jeopardized by for example adverse events and most of the current evidence on adverse ...
  • PGE2 and other lipids in rheumatic diseases 

    Raouf, Joan (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-02-21)
    Despite numerous options for treatment of rheumatic diseases, there is an unfulfilled clinical need for therapeutic strategies that can reduce inflammation and prevent tissue destruction. Lipid mediators (eicosanoids and ...
  • The male predominance in esophageal adenocarcinoma 

    Xie, Shaohua; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-02-21)
    The incidence of esophageal adenocarcinoma (EAC) has increased rapidly during the past four decades in many Western populations, including North America and Europe. The established etiological factors for EAC include ...
  • Duration of Second Stage of Labour at Term and Pushing Time: Risk Factors for Postpartum Haemorrhage 

    Looft, Emelie; Simic, Marija; Ahlberg, Mia; Snowden, Jonathan M.; Cheng, Yvonne W.; Stephansson, Olof (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-02-21)
    BACKGROUND: Prolonged labour is associated with increased risk of postpartum haemorrhage (PPH), but the role of active pushing time and the relation with management during labour remains poorly understood. METHODS: A ...
  • Samverkan och lärande kring sårbehandling : erfarenheter från olika professionsperspektiv i primärvård och utbildning 

    Friman, Anne (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2017-02-20)
    Aim: The overall aim of this thesis is to explore collaboration and knowledge development in wound management in practice and in education. One specific aim is to investigate district nurses’ (DNs’) wound management ...
  • Methodological aspects on carotid artery intervention 

    Jonsson, Magnus (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2017-02-17)
    In Sweden, approximately 25000 patients suffer a cerebral infarction (stroke) annually. Stroke ranks as the third-leading cause of death, and is the leading cause of functional impairment. Carotid artery stenosis accounts ...
  • Elderly patients undergoing colorectal cancer surgery : can care be further improved? 

    Schubert Samuelsson, Katja (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-17)
    Introduction: Colorectal cancer (CRC) is one of the most common malignancies affecting approximately 6 400 new patients/year in Sweden of which 44% are 75 years and older at diagnosis. In order to identify potential ...
  • Porphyrins and phototherapy of oral bacteria 

    Bjurshammar, Nadja (Inst för odontologi / Dept of Dental Medicine, 2017-02-16)
    In the mid-1990s researchers became interesting in blue light-based therapies using light- emitting diodes (LED) light. Blue light therapy has been successfully used in treatment of acne, as well as shown wound healing ...
  • Genetic and lifestyle influences on memory, brain structure, and dementia 

    Ferencz, Beata (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-16)
    This doctoral thesis investigated genetic, inflammatory, and lifestyle influences on cognition, brain structure, and dementia. The influence of TOMM40 polymorphisms (Study I), a PICALM, BIN1 and CLU genetic risk score ...
  • A model for predicting individuals' absolute risk of esophageal adenocarcinoma : moving toward tailored screening and prevention 

    Shaohua, Xie; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-02-15)
    Esophageal adenocarcinoma (EAC) is characterized by rapidly increasing incidence and poor prognosis, stressing the need for preventive and early detection strategies. We used data from a nationwide ...
  • Experimental, mild blast-induced traumatic brain injury : focus on the monoamine and galanin systems 

    Kawa, Lizan (Inst för neurovetenskap / Dept of Neuroscience, 2017-02-14)
    Traumatic brain injury (TBI) is a common cause of mortality and morbidity among civilians and servicemen alike. The spectrum of TBIs encompasses mild to severe cases, with the predominate number of TBIs being mild (mTBI). ...
  • Identification of biobehavioral markers of neurodevelopmental disorders in twins 

    Willfors, Charlotte (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-02-10)
    Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are complex neurodevelopmental disorders (NDD), heterogeneous in phenotypes and etiology. The exact mechanisms driving the phenotypes are ...
  • Apolipoprotein E and cholinergic enzymes : the interface in dementia 

    Vijayaraghavan, Swetha (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-10)
    The main confirmed genetic risk factor for sporadic form of Alzheimer’s disease (AD) is apolipoprotein E (ApoE) ε4 allele (APOE4). ApoE protein aids in receptor ligand mediated transport, distribution and metabolism of ...
  • Molecular and epigenetic control of CNS tumour and progenitor cells 

    Gracias, Aileen (Inst för neurovetenskap / Dept of Neuroscience, 2017-02-09)
    Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances ...
  • Quality of life in men with inguinal hernia and outcome after three different mesh techniques 

    Magnusson, Jesper (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2017-02-08)
    Inguinal hernia repair (IHR) is a very common surgical procedure with approximately 16 000 procedures performed every year in Sweden. Previously, recurrence after IHR was a major concern, but with the introduction of the ...
  • Atrial fibrillation and lifestyle factors with focus on physical activity and alcohol consumption 

    Drca, Nikola (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2017-02-06)
    The overall aim of this thesis was to investigate how modifiable lifestyle factors, with a focus on alcohol consumption and physical activity, influence the risk of atrial fibrillation (AF). The thesis is based on data ...
  • Liver regeneration and function following portal vein occlusion and hepatectomy 

    Sparrelid, Ernesto (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-06)
    Background: Portal vein occlusion (PVO) and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) are two strategies employed to render patients with unresectable liver tumours resectable ...
  • Purification and biodistribution of extracellular vesicles 

    Nordin, Joel Z. (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2017-02-06)
    Extracellular vesicles (EVs) are nano-sized vesicles that contain bioactive lipids, RNAs and proteins, which can be transferred to recipient cells. EVs are important for physiological as well as pathological processes, ...