Now showing items 1-20 of 7342

  • Identifying individual antibiotic treatments prescribed for mothers and for children up to the age of five following specific inpatient diagnoses 

    Almqvist, C.; Örtqvist, A.K.; Gong, T.; Wallas, A.; Ahlén, K.M.; Ye, W.; Lundholm, C. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Aim: Exposure to antibiotics in early life may affect future health. Most antibiotics are prescribed in outpatient care, but inpatient exposure is also important. We estimated how specific diagnoses in hospitals corresponded ...
  • Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency 

    Falhammar, H.; Frisén, L.; Norrby, C.; Linden Hirschberg, A.; Almqvist, C.; Nordenskjöld, A.; Nordenström, A. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
    Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ...
  • Similar familial risk in multiple sclerosis subgroups Introduction 

    Song, J.; Karrenbauer, V.; Manouchehrinia, A.; Almqvist, C.; Hillert, J.; Westerlind, H. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
  • Gut microbes and the developing brain 

    Arentsen, Tim B. F. (Inst för neurovetenskap / Dept of Neuroscience, 2017-03-17)
    The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases. A ...
  • Exposure to air pollution from traffic and neurodevelopmental disorders in Swedish twins 

    Gong, T.; Almqvist, C.; Bolte, S.; Lichtenstein, P.; Anckarsater, H.; Lind, T.; Lundholm, C.; Pershagen, G. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-17)
    Background: Recent studies have reported associations between air pollution exposure and neurodevelopmental disorders in children but the role of pre- and postnatal exposure has not been elucidated. Aim: We aimed ...
  • Breast cancer in young women : aspects on mortality and local recurrence 

    Fredholm, Hanna (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-17)
    The general aim of the thesis was to gain increased insight into the long-term prognosis for young women with breast cancer. In a population-based cohort of 22,017 women with breast cancer, we studied prognosis by ...
  • CNS tumours of childhood/adolescence : outcomes related to disability and identity in adult survivors 

    Hörnquist, Lina Olivia (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-03-16)
    Central nervous system (CNS) tumour survivors are at increased risk for adverse health and functional late effects. Results from previous studies from the Swedish LIFE project, of which this licentiate thesis is a part, ...
  • Thioredoxin and Glutaredoxin systems under oxidative and nitrosative stress 

    Ren, Xiaoyuan (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2017-03-16)
    Our knowledge about reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been changed from simple damaging molecules to redox signaling mediators. ROS/RNS mediated signaling is mainly based on the reversible ...
  • Complicated peptic ulcer disease : prevention and treatment 

    Sverdén, Emma (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-15)
    Peptic ulcer is a common disease worldwide and its complications can cause serious clinical problems. While the incidence of uncomplicated peptic ulcer disease is decreasing, the incidence of more complex ulcer disease is ...
  • The function of Smc5/6 in Drosophila development and at the heterochromatin-like locus HMR in budding yeast 

    Tran, Martin (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2017-03-15)
    The structural maintenance of chromosome 5/6 (Smc5/6) complex is one out of many factors in the cell that maintain genome stability. Smc5/6 has been implicated in processes such as DNA double-strand break (DSB) repair, ...
  • The association between caesarean section and asthma or allergic disease continues to challenge 

    Almqvist, Catarina; Öberg, Anna Sara (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
  • Exploring disease biomarkers and mechanisms using metabolomics 

    Lindahl, Anna (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2017-03-14)
    A metabolome is the complete set of small molecules or metabolites present in a biological system. It is the result of internal, genetically determined processes, as well as external factors. The metabolome can consequently ...
  • Twins' risk of childhood asthma mediated by gestational age and birthweight 

    Ullemar, Vilhelmina; Lundholm, Cecilia; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Background: Children born with low gestational age (GA) or low birth weight (BW) are at increased risk of asthma. Twins as compared to singletons are on average more likely to be born with lower GA and BW, and have been ...
  • Predictors of adolescents' consent to use health records for research and results from data collection in a Swedish twin cohort 

    Ullemar, Vilhelmina; Lundholm, Cecilia; Örtqvist, Anne; Gumpert, Clara Hellner; Ancarsäter, Henrik; Lundström, Sebastian; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Introduction: Nonrandom selection into a study population due to differences between consenters and non-consenters may introduce participation bias. Past investigations of factors predicting consent to collection of ...
  • Increased risk for substance use-related problems in autism spectrum disorders : a population-based cohort study 

    Butwicka, A.; Langstrom, N.; Larsson, H.; Lundstrom, S.; Serlachius, E.; Almqvist, C.; Frisen, L.; Lichtenstein, P. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 ...
  • Time trends in the incidence of oesophageal cancer in Asia : variations across populations and histological types 

    Xie, Shaohua; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-14)
    OBJECTIVE: We aimed to assess temporal trends in incidence rates of oesophageal cancer in Asian countries. MATERIALS AND METHODS: Using data from the Cancer Incidence in Five Continents series, we ...
  • Air pollution exposure during pregnancy and childhood autistic traits in four European population-based cohort studies : the ESCAPE project 

    Guxens, M.; Ghassabian, A.; Gong, T.; Garcia-Esteban, R.; Porta, D.; Giorgis-Allemand, L.; Almqvist, C.; Aranbarri, A.; Beelen, R.; Badaloni, C.; Cesaroni, G.; de Nazelle, A.; Estarlich, M.; Forastiere, F.; Forns, J.; Gehring, U.; Ibarluzea, J.; Jaddoe, V.W.; Korek, M.; Lichtenstein, P.; Nieuwenhuijsen, M.J.; Rebagliato, M.; Slama, R.; Tiemeier, H.; Verhulst, F.C.; Volk, H.E.; Pershagen, G.; Brunekreef, B.; Sunyer, J. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Background: Prenatal exposure to air pollutants has been suggested as a possible etiologic factor for the occurrence of autism spectrum disorder. Objectives: We aimed to assess whether prenatal air pollution exposure ...
  • Perinatal exposure to traffic-related air pollution and autism spectrum disorders 

    Gong, T.; Dalman, C.; Wicks, S,; Dal, H.; Magnusson, C.; Lundholm, C.; Almqvist, C.; Pershagen, G. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Background: Studies from the United States indicate that exposure to air pollution in early life is associated with autism spectrum disorders (ASD) in children, but the evidence is not consistent with European ...
  • Population-based data on asthma and allergic disease call for advanced epidemiologic methods 

    Almqvist, Catarina; Lundholm, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
  • Cohort profile : Swedish Twin Study on Prediction and Prevention of Asthma (STOPPA) 

    Almqvist, Catarina; Örtqvist, Anne K; Ullemar, Vilhelmina; Lundholm, Cecilia; Lichtenstein, Paul; Magnusson, Patrik K E (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Asthma is a common childhood disease and several risk factors have been identified, however the impact of genes and environment is not fully understood. The aim of the Swedish Twin study On Prediction and Prevention of ...