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  • Epidemiological studies of fructosamine in relation to diabetes, cardiovascular disease and mortality 

    Malmström, Håkan (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-04-20)
    BACKGROUND: Diabetes is associated with an increased risk of micro- and macrovascular disease and mortality. Two main methods for diagnosis and control of type 2 diabetes are the measurements of blood glucose and glycosylated ...
  • Interaction of genetic and environmental factors in childhood asthma and allergy 

    Gref, Anna (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-04-07)
    Asthma and allergy are the most common chronic childhood diseases. Their occurrences are influenced by both genetic and environmental factors, although the underlying mechanisms are not fully understood. The overall ...
  • Cancer mortality and survival after cancer diagnosis by migration background and socioeconomic position in Sweden 

    Abdoli, Gholamreza (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-03-09)
    Aims: The overall aim of this thesis was to investigate the risk of cancer mortality and survival after cancer diagnosis based on migration background and socioeconomic position in Sweden. We studied the effects of country ...
  • Long-term exposure to air pollution from road traffic and lung function in children and adolescents 

    Schultz, Erica S (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-11-10)
    Lung function in early life is an important predictor of peak lung function and later decline in adults. However, lung development may also be influenced by factors later in childhood and adolescence. Identification of ...
  • Physiologically based modelling of nanoparticle biodistribution and biokinetics 

    Carlander, Ulrika (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-11-08)
    To predict the toxicity of nanoparticles (1-100 nm), it is crucial to understand their biokinetics i.e. how they are taken up, distributed, dissolved and removed from the body. Such information can be gained from biodistribution ...
  • Nutritional factors and allergic disease : from infancy to adolescence 

    Magnusson, Jessica (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-11-03)
    Allergic disease is one of the most common non-communicable diseases in childhood. Both overweight and diet have been hypothesized to influence the risk of allergic disease. The aim of this thesis was to investigate the ...
  • Worth weighting for : studies on benchmark dose analysis in relation to animal ethics in toxicity testing 

    Ringblom, Joakim (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-10-27)
    A purpose of chemical health risk assessment is to characterize the nature and size of the health risk associated with exposure to chemicals, including identification of a dose below which toxic effects are not expected ...
  • Nanotoxicology on the right track : focus on metal and metal oxide nanoparticles 

    Gliga, Anda R. (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-10-14)
    The last decade has seen a rapid increase in the manufacture and use of nanomaterials, a development which should be met with appropriate safety assessment strategies in order to ensure the sustainable development of ...
  • The health economics of Duchenne muscular dystrophy 

    Landfeldt, Erik (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-09-30)
    Duchenne muscular dystrophy (DMD) is a rare neuromuscular disease characterized by progressive muscle degeneration resulting in loss of independent ambulation, serious multisystem complications, and a mean life expectancy ...
  • Recurrent and persistent low back pain : course and prevention 

    Eklund, Andreas (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-09-14)
    Background: Non-specific low back pain (LBP) causes more disability than any other condition in the world. The need to understand the clinical course of LBP, develop effective strategies to manage and if possible prevent ...
  • Vitamin D and multiple sclerosis: epidemiological studies on environmental and genetic risk factors 

    Bäärnhielm, Maria (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-08-24)
    Background: Multiple sclerosis (MS) is an autoimmune inflammatory neurological disease with complex aetiology where the causes are not completely known. The main aim of this thesis was to investigate the influence of vitamin ...
  • 5-Fluorouracil mediated cell death signaling
 in colon carcinoma cells 

    Akpinar, Birce (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-06-07)
    Colorectal cancer (CRC) is the third most common form of cancer in the world. 5- Fluorouracil (5-FU) belongs to the fluoropyrimidine-type of drugs and is commonly used in the treatment of several solid tumors. It has become ...
  • Diet and risk of acute pancreatitis 

    Oskarsson, Viktor (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-05-11)
    Acute pancreatitis is a sudden inflammation of the pancreas. It has a broad spectrum of clinical outcomes, ranging from mild and self-limiting to severe and potentially fatal, and is often followed by recurrent attacks ...
  • Lifestyle and risk of abdominal aortic aneurysm 

    Stackelberg, Otto (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-04-29)
    Background Lifestyle-related factors associated with abdominal aortic aneurysm (AAA) disease are very scarcely investigated in prospective design. Identification of such could provide better understanding of AAA ...
  • Fish consumption in relation to type 2 diabetes and cardiovascular complications 

    Wallin, Alice (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-03-31)
    Type 2 diabetes is a major public health threat globally, associated with severe medical complications such as cardiovascular diseases and damage to kidneys, eyes, and nerves, as well as with premature death. Dietary factors ...
  • Mobility on the labour market, work ability and sick leave 

    Nordström, Karin (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-03-31)
    The overall aim of this thesis is to study the potential causes and effects of mobility on the labour market among individuals with reduced work ability or who experience long-term sick leave. Long-term sick leave is ...
  • Comorbidity in risk and outcome of hematological malignancies 

    Mohammadi, Mohammad (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-03-01)
    Hematological malignancies are a group of neoplasms that originate from the bone marrow or lymphatic tissues representing close to 10% of the overall cancer burden in the world. Clinical course, prognosis and survival ...
  • Alcohol, tobacco and the risk of LADA-latent autoimmune diabetes in adults 

    Rasouli, Bahareh (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-02-26)
    Diabetes is a common and increasing public health problem. Knowledge of risk factors is a prerequisite for efficient prevention; such knowledge is extensive for type 2 diabetes but limited for autoimmune forms of diabetes. ...
  • Transcriptional and epigenetic regulation of gene expression by arsenic in cancer and normal cells 

    Pournara, Angeliki (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-02-18)
    Inorganic arsenic is a toxic metalloid that occurs naturally on the earth’s crust. Millions of people worldwide are exposed to inorganic arsenic via drinking water, and more recently also via contaminated food, in particular ...
  • Tobacco and multiple sclerosis susceptibility 

    Hedström, Anna Karin (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-01-28)
    Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS) that arises from a combination of a complex genetic predisposition and environmental factors. For northern Europeans, the ...

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