Doktorsavhandlingar / Doctoral Theses - C8 (MEB): Recent submissions
Now showing items 201-220 of 250
-
Hormone-related factors and breast cancer : studies of risk and prognosis
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-08-18)The main purpose of this thesis was to explore the influences of risk factors for breast cancer on breast cancer characteristics and survival. We evaluated the associations between number and timing of births and ... -
Genetic studies of depressive symptoms
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2004-02-06)This thesis is focused on depressive symptoms particularly in late fife. Depressive symptoms are associated with serious negative outcomes a greater level of disability and with excess morbidity and mortality. This thesis ... -
Spontaneous abortion : risk factors and measurement of exposures
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-09-22)The overall objectives of this thesis were to increase the understanding of the etiology of spontaneous abortion and repeated spontaneous abortion, and to evaluate possibilities of exposure assessment during pregnancy. Data ... -
Cervical carcinoma in Kampala, Uganda, and the relationship with human immunodeficiency virus and human papillomavirus infections
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2010-10-25)Introduction: Cervical carcinoma is the commonest tumour in Ugandan women. However, very little is known in the Ugandan population about HPV types associated with invasive cervical cancer, the relative risk of cervical ... -
Epidemiological studies on complications in type 1 diabetes
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2008-03-14)The main threat to the health of patients with type 1 diabetes (T1DM) is its complications. This thesis aimed to assess the risks of hip fracture, non-trauma lower extremity amputation (LEA) and myocardial infarction in ... -
Malignancies associated with gynecological cancer : epidemiological and etiological aspects
(Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2001-10-26)The aims of this thesis were to analyze the incidence and risk of second primary malignancies (SPM) in a Swedish cohort of gynecological cancer patients, to explore suggested risk factors associated with second primary ... -
E-epidemiology : adapting epidemiological methods for the 21st century
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-08-28)The traditional methods in epidemiological data collection are both costly and time consuming and less convenient for longitudinal large-scale studies. During the last decades, epidemiological studies suffer from low ... -
Psychopathic personality in adolescence : genetic and environmental influences
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-09-04)Psychopathy, or psychopathic personality, is a personality disorder characterized by a constellation of deviant interpersonal, affective, and behavioral dimensions. It has consistently been shown that the psychopathic ... -
Human salmonellosis : impact of travel and trade from a Swedish perspective
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-09-08)Background: Salmonellosis is one of the most important gastrointestinal infections in humans. The vast majority of Swedish Salmonella cases have acquired the disease abroad, reflecting both a large number of Swedish ... -
Human papillomaviruses and their association with squamous cell carcinoma of the conjunctiva
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-10-07)Squamous cell carcinoma of the conjunctiva (SCCC), hitherto a rare cancer, has increased manyfold since the advent of HIV/AIDS. Solar ultra violet radiation (UV) may also be a risk factor for the disease. The increased ... -
Risk factors for the development of chronic renal failure : epidemiological studies on the role of analgesic use, occupational exposures and socioeconomic background
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2003-01-17)Chronic renal failure is a severe condition that reduces life expectancy and typically progresses to end-stage renal disease and a need for renal replacement therapy. In a large proportion of cases, chronic renal failure ... -
Adolescent adjustment problems : the role of heritability and family environment
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-08-21)Approximately one fifth of children and adolescents in Europe and United States of America suffer from behavioral, emotional or developmental problems. More effective prevention and intervention of these problems may be ... -
Risk and prognosis of breast cancer among women at high risk of the disease
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2007-09-21)The overall objectives of this thesis were to increase our understanding of the risk and prognosis of breast cancer using the high risk groups of women with bilateral and familial breast cancer. Data from the Swedish ... -
The risk of malignancy in women with endometriosis
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2010-03-05)The aim of this thesis was to investigate the association between endometriosis and malignancies also after controlling for parity, to investigate the impact of endometriosis on survival after a malignancy diagnosis and ... -
Statistical genetic analysis of family data
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2008-08-22)The importance of genetic determinants and risk factors of diseases has been consistently recognized in genetic epidemiology, which is one of the fastest growing areas in genomic medicine. Familial clustering is a common ... -
Genetic epidemiological studies of adverse pregnancy outcomes and the role of schizophrenia
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-02-24)The purposes of this thesis were to investigate the importance of genetic and environmental factors in the development of adverse pregnancy outcomes and to investigate the role of schizophrenia as a risk factor for and a ... -
Infections and infectious related morbidity during pregnancy : short and long-term effects
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2008-11-28)The aim of this thesis was to elucidate the association between infections during pregnancy and risks of miscarriage, preterm delivery and later development of autism. We identified 60 755 women with singleton ... -
Risk factors for cervical cancer development
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2007-11-23)Cervical cancer remains one of the leading causes of cancer mortality globally, predominantly in less developed countries. It is widely accepted that certain oncogenic types of HPV (Human papillomavirus) are necessary ... -
Studies of genetic and environmental influences on Parkinson’s disease
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2004-01-30)Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. Little is known about the etiology of PD. Although several PD genes are known, these are thought to be involved in ... -
Genetic epidemiological approaches to the study of risk factors for cardiovascular diseases
(Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2003-05-07)Cardiovascular disease (CVD) is one of the most common causes of death in most developed countries. Genetic and environmental factors influence CVD and its risk factors in a complex fashion. Parallel to this, new statistical ...