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  • Attention-deficit/hyperactivity disorder and adverse health outcomes : from association to prevention 

    Sun, Shihua (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-11-23)
    Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed neurodevelopmental disorder, characterized by persistent inattention and/or hyperactivity-impulsivity that are inappropriate for one’s developmental ...
  • Dietary habits, commensal microbiome, and nasopharyngeal carcinoma 

    Huang, Tingting (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-11-19)
    Nasopharyngeal carcinoma (NPC) is a malignant disease characterized by unique geographic distribution endemic to southern China, Southeast Asia, and the Middle East/North Africa. It has been widely accepted that the ...
  • Determinants and influence of mammographic features on breast cancer risk 

    Azam, Shadi (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-11-16)
    Mammographic density and mammographic microcalcifications are the key imaging features in mammography examination. Mammographic density is known as a strong risk factor for breast cancer and is the radiographic appearance ...
  • Investigations of body mass, gastrointestinal, and dietary factors influencing the emergence and maintenance of eating disorders 

    Wiklund, Camilla (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-10-20)
    Eating disorders are severe psychiatric illnesses, characterized by dysregulated eating and distorted attitudes toward weight and body shape, causing enormous suffering for patients and their families. Although great ...
  • Molecular epidemiology studies on risk factors for breast cancer and disease aggressiveness 

    Ugalde Morales, Emilio (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-09-10)
    Breast cancer is a heterogeneous disease. Aggressive subtypes are characterized by faster growth rates, increased capability to invade and metastasize, leading to poorer clinical outcomes. In this thesis, we use a molecular ...
  • Novel statistical methods for genome-wide association summary statistics 

    Ning, Zheng (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-08-20)
    A general objective of genetic studies is to understand the genetic basis of complex traits such as height, body mass index (BMI), disease endpoints, etc. Such researches have been facilitated due to the completion of ...
  • Etiology and prognosis of gastroesophageal cancers 

    Ekheden, Isabella (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-05-19)
    Gastric and esophageal cancer – gastroesophageal cancers, belong to the most fatal malignancies in the world. Understanding the cause of these diseases is key to interventions such as primary prevention and/or surveillance ...
  • Personality, stress and risk of Parkinson's disease 

    Sieurin, Johanna (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-05-08)
    The objective of this thesis was to investigate the relationship of personality and stress with subsequent risk of Parkinson’s disease (PD). In Study I, we conducted a population-based cohort study using questionnaire ...
  • Artificial intelligence for streamlining prostate cancer diagnostics 

    Ström, Peter (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-24)
    With around 1.2 million cases per year, prostate cancer is the second most common cancer among men. It is usually a slow growing disease that affects older men. It is also a cancer that is heterogenous, often multifocal, ...
  • Stress during cancer diagnostic workup 

    Shen, Qing (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-03-24)
    Receiving a cancer diagnosis is an extremely stressful life event. Cancer patients have been reported to experience an excessive risk of stress-related health outcomes including suicide. The time period between the first ...
  • Prevention and prognosis of cervical cancer : the interplay of human papillomavirus, vaccination and screening 

    Lei, Jiayao (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-02-26)
    Human papillomavirus (HPV) is the major cause of cervical cancer. The well-established natural history from HPV infection to the occurrence of invasive cervical cancer serves as the basis for prevention of cervical cancer ...
  • Epidemiological studies on socioeconomic inequalities and cardiovascular disease : prevention, progression and prognosis 

    Malki, Ninoa (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-02-20)
    Cardiovascular disease (CVD) accounts for 30% of global mortality and is the most common cause of death in the world. Population-wide prevention strategies as well as healthcare interventions have led to a decrease in ...
  • DNA methylation and aging : a longitudinal study of old Swedish twins 

    Wang, Yunzhang (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-01-09)
    DNA methylation is a well-known biomarker of aging. Many previous studies have reported the change of DNA methylation patterns with age, and analyzed DNA methylation in association with aging outcomes. However, most ...
  • Amyotrophic lateral sclerosis and multiple sclerosis associated neuroinflammation : nationwide epidemiological studies on etiology, comorbidities, and treatment 

    Longinetti, Elisa (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-11-26)
    Amyotrophic lateral sclerosis (ALS) is a relatively rare but fatal neurodegenerative disease characterized by progressive muscle paralysis, due to loss of upper and lower motor neurons. Signs of neuroinflammation have been ...
  • Epidemiology, prevention and control of Legionnaires’ disease in Europe 

    Beauté, Julien (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-11-22)
    Legionnaires’ disease (LD) is a water-borne infection cause by Gram-negative bacteria Legionella spp. with virtually no person-to-person transmission. The clinical presentation is a severe pneumonia with a case fatality ...
  • Statistical models of breast cancer tumour growth and spread 

    Isheden, Gabriel (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-11-18)
    In this thesis, we develop statistical methods for studying tumour growth and metastatic lymph node spread in breast cancer. The methods can be used for analysing breast cancer disease progression before diagnosis. They ...
  • Sex differences in cancer risk and survival 

    Radkiewicz, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-11-15)
    Aim: The objective of study I was to delineate and quantify sex differences in cancer risk and survival together with assessing the potential gain achieved by eliminating the excess cancer risk in men. Study II and III ...
  • The comorbidity between attention-deficit/hyperactivity disorder and other neurodevelopmental disorders : aetiology, treatment and outcomes 

    Ghirardi, Laura (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-09-17)
    Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder (ND) defined by the presence of impairing levels of inattentiveness, hyperactivity, and impulsivity. These symptoms are often accompanied ...
  • Socioeconomic influences on late-life health and mortality : exploring genetic and environmental interplay 

    Ericsson, Malin (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-09-13)
    The objective of this thesis was to increase the understanding of socioeconomic differences in health and mortality in old age - in a genetically informative setting. Data from the Swedish Twin Registry (STR), different ...
  • Risk prediction in prostate cancer diagnostics : current challenges and improvements 

    Palsdottir, Thorgerdur (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-30)
    Prostate cancer has been considered a disease of elderly men, and thus historically less focus has been on prostate cancer research than many other cancer types. However, as life expectancy is increasing all over the world, ...

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