Doktorsavhandlingar / Doctoral Theses - C8 (MEB): Recent submissions

Now showing items 181-200 of 250

    • Genetic determinants of breast cancer risk 

      Li, Jingmei (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2011-01-19)
      The main purpose of this thesis was to identify genetic risk factors using both hypothesis-based and hypothesis-free approaches. In an attempt to identify common disease susceptibility alleles for breast cancer, we ...

    • Web-based studies of lifestyle factors and immune function 

      Fondell, Elinor (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2011-01-17)
      Upper respiratory tract infection (URTI), is estimated to cost $40 billion per year in the US, not including the cost of influenza, and is the most common reason for seeking primary care in many countries. Despite this, ...

    • Very preterm birth : etiological aspects and short and long term outcomes 

      Johansson, Stefan (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2008-03-28)
      Very preterm birth, occurring before 32 completed weeks of gestation, is an often unexplained pregnancy complication affecting approximately 1 to 2 percent of all births. This thesis includes four studies regarding ...

    • Dietary and genetic factors in the etiology of prostate cancer 

      Hedelin, Maria (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-05-19)
      The etiology of prostate cancer is poorly understood. However, genetic factors may be more important than for many other malignancies. In addition, several studies suggest that dietary factors axe of etiologic importance. ...

    • Early cervical lesions detected by visual inspection : viral factors, management and follow-up 

      Mutyaba, Twaha Serunjogi (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-10-09)
      Currently 80% of cervical cancer cases worldwide arise in low income countries. In Uganda, the age standardized incidence rate of cervical cancer is estimated at 40.7 per 100,000 women. Public health policies, logistical, ...

    • Endogenous and exogenous hormonal factors in female cancers : studies of risk and prognosis 

      Orgéas, Chantal Claudine (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-02-06)
      Extensive evidence points to hormonal influences which play a critical role in the development and progression of breast, ovarian and endometrial or uterine cancers. These cancers share many common hormonal features, ...

    • Renal cell cancer : the role of physical activity and body size 

      Bergström, Anna (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2001-02-02)
      The aim of this thesis was to explore how physical activity, obesity, weight change, and birth weight influence the risk of renal cell cancer. The relation between occupational physical activity and risk of renal ...

    • Aspects of Helicobacter pylori transmission 

      Kivi, Mårten (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2005-09-30)
      The bacterium Helicobacter pylori infects the gastric mucosa of about half of the world's population. The infection causes gastritis and contributes to the development of peptic ulcer disease and gastric cancer. H. pylori ...

    • The risk of second primary lung carcinoma in breast cancer patients 

      Prochazka, Michaela (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-02-03)
      The overall aim of this thesis was to investigate the risk of second primary malignancies - with a special focus on lung cancer - in a cohort of approximately 152,000 Swedish women diagnosed with breast cancer between 1958 ...

    • Some lifestyle-related factors and risk of chronic renal failure : a population-based approach 

      Ejerblad, Elisabeth (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2005-02-11)
      Some renal diseases, i.e. rapidly progressive glomerulonephritis, are sufficient causes of a rapid, permanent total loss of renal function. However, the majority of renal diseases progress slowly over decades, initially ...

    • Human papillomavirus infections among sexually active young women in Uganda : implications for a vaccination strategy 

      Banura, Cecily (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-10-05)
      Introduction: Information about the genital (human papilloma virus) HPV infection is needed to support the introduction of HPV vaccination in Uganda. Objectives: (i) To estimate the prevalence, incidence, clearance ...

    • Some hormonal factors in the etiology of endometrial cancer 

      Weiderpass, Elisabete (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 1999-05-17)
      The main purpose of this dissertation was to study the impact of some hormone-related factors in the etiology of endometrial neoplasms, i.e. hormone replacement therapy, use of oral contraceptives, serum levels of 20 ...

    • Occupational and socio-economic factors in the etiology of cancer of the esophagus and gastric cardia 

      Jansson, Catarina (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2005-09-16)
      Adenocarcinoma of the esophagus and gastric cardia and squamous-cell carcinoma of the esophagus have a poor prognosis. The increasing incidence and the strong male predominance of esophageal and cardia adenocarcinoma are ...

    • An epidemiologic study of epithelial ovarian malignancies : with a focus on hormone-related factors 

      Riman, Tomas (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2003-01-03)
      The main purpose of this thesis was to examine estrogen and progestin effects of hormone replacement therapy, in relation to the risk for epithelial ovarian neoplasias. Other intentions were to assess reproductive factors, ...

    • Roles of Helicobacter pylori infection, host genetic variation, and other environmental exposures in gastric carcinogenesis 

      Persson, Christina (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2009-11-06)
      Despite a general declining secular trend of incidence in most parts of the world, stomach cancer is still a major cause of cancer-related death worldwide due to its poor prognosis. Although Helicobacter pylori (H. pylori) ...

    • Genetic and environmental factors in the development of externalizing symptoms from childhood to adolescence 

      Larsson, Henrik (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2005-11-11)
      Externalizing problems, such as hyperactivity, impulsivity, aggression, violation of legal or social norms, and delinquent behavior, tend to persist from childhood to adolescence. There are also high levels of comorbidity ...

    • Etiological aspects of gastroesophageal cancers : an epidemiological approach 

      Bahmanyar, Shahram (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2007-09-14)
      Aims: The aims of this thesis were to study the association of overall dietary habits, duodenal ulcer and gastric ulcer diseases, as two models of Helicobacter pylori (H. pylori) infection and the development of gastroesophageal ...

    • Genetic and environmental influences on antisocial behavior from childhood to emerging adulthood 

      Tuvblad, Catherine (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2006-11-02)
      Antisocial behavior, in other words, normative and rule-breaking behavior, is a major problem in societies all over the world. Because many antisocial behavioral problems start in childhood or adolescence, the study of ...

    • Blood donors' long-term health : implications for transfusion safety 

      Edgren, Gustaf (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2007-11-12)
      Continuous attention to transfusion safety through improvement of disease screening and donor selection has succeeded in reducing the risks of transfusion transmitted disease to practically immeasurable levels. Despite ...

    • Inflammation-associated risk factors for Alzheimer's disease and dementia 

      Eriksson, Ulrika K (Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics, 2010-02-19)
      Alzheimer's disease (AD) is the leading cause of dementia worldwide and a highly debilitating, and deadly, disease. For the majority of AD cases, the cause of the disease is not known. Chronic inflammation has been implicated ...