Doktorsavhandlingar / Doctoral Theses - C8 (MEB): Recent submissions
Now showing items 141-160 of 250
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Creativity and psychopathology
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-02-28)The Mad Genius is a recurring stereotype of contemporary cultural expression. However, starting with Lombroso’s investigation of genius and madness in 1888, recent decades have seen an increasing number of empirical studies ... -
Statistical methods for long-term follow-up of infectious diseases
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-02-21)The overall aim of this work has been to investigate methodological issues connected to long-term follow-up of infections diseases. The work extended to prevalent cohorts in general. The common denominator for the main ... -
Diet in epidemiology : assessment, validity and association with upper respiratory tract infection
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-02-14)This thesis covers the evaluation of two new interactive web- and meal-based food frequency questionnaires (FFQ). In addition, it investigates the potential association between dietary intake as well as physical activity ... -
Twin and family studies on the development of cognitive and externalizing problems
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-02-03)Cognitive and externalizing problems are responsible for much personal suffering, as well as large monetary costs for society. Intervention and prevention efforts have often failed in reduction of unwanted behaviors, perhaps ... -
Parental characteristics and offspring internalizing behaviors : understanding the associations using quantitative genetics
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-12-19)Internalizing problems increase dramatically from childhood to adolescence and account for a large proportion of mental health problems worldwide. During the past decade research has documented a robust association between ... -
If I only had a brain : epidemiological studies of Parkinson's disease
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-12-12)Parkinson’s disease (PD) is an aging-related movement disorder caused by selective degeneration of dopaminergic neurons in the substantia nigra in the midbrain. Onset of PD symptoms, which include tremor, bradykinesia and ... -
Development and application of statistical methods for population-based cancer patient survival
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-10-29)The overarching aim of this work has been to develop and apply statistical methods for estimating cancer patient survival from population-based register data. Particular focus has been on statistical methods that can be ... -
Epidemiological studies of diet quality, body size and prostate cancer risk
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-10-24)Prostate cancer is the most common male cancer in high-income countries. The etiology of the disease is still poorly understood, but increasing evidence suggests that lifestyle factors such as diet and body size play an ... -
Quantifying cancer patient survival : extensions and applications of cure models and life expectancy estimation
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-10-18)Cancer patient survival is the single most important measure of cancer patient care. By quantifying cancer patient survival in different ways further insights can be gained in terms of temporal trends and differences in ... -
The origins and consequences of attention deficit hyperactivity disorder
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-10-18)Attention deficit hyperactivity disorder (ADHD) is characterized by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity, and is the most common neurodevelopmental disorder of childhood. This ... -
High paternal age and risk of psychiatric disorders in offspring
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-10-08)Parental ages at childbirth are increasing all over the world and later parenthood might have negative health outcomes for the offspring. During recent year, numerous studies report links between and high paternal age and ... -
Studies on risk factors for urinary incontinence in Swedish female twins
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-09-20)Approximately half of all women in industrialized countries will experience urinary incontinence during their lifetime. Even though urinary incontinence is not a life threatening disease, it often has severe implications ... -
Development of methods for population-based surveillance of influenza
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-09-16)When this work was initiated the infectious disease surveillance systems available to public health authorities in Sweden and elsewhere were not providing continuously updated information on individuals stricken by disease ... -
Risk factors for esophageal squamous cell carcinoma
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-09-11)Aims: The etiology of esophageal squamous cell carcinoma (ESCC) in the high risk areas is largely unknown and a few environmental risk factors which have been identified do not explain its oddly high incidence in esophageal ... -
Genetic predisposition and dietary factors in relation to adiponectin and insulin resistance
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-08-30)Diabetes mellitus is a global health problem, owing to the high prevalence and enormous associated economic burden. Insulin resistance is a critical condition to the development of type 2 diabetes (T2D). Adiponectin, a ... -
Cervical cancer : incidence, screening and prognosis among immigrant women in Sweden
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-08-09)Immigrant studies may help further our understanding of the aetiology of cervical cancer and improve its prevention. The overall aim of this thesis is to study the risk of cervical cancer among immigrant women in Sweden, ... -
Methods for deep examination of DNA
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-05-08)The development of sequencing technology has had a rapid pace during the last years and today, the sequencing instruments harbors enormous capacity. This thesis is about the development of methods to make the most out of ... -
Molecular and psychosocial risk factors for cardiovascular disease
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-03-26)Cardiovascular disease (CVD) is the leading cause of mortality globally, and a major contributor to disability. There exist several well-established CVD risk factors, many of which are used in clinical practice. Nonetheless, ... -
Social mobility in relation to cardiovascular and psychiatric health
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-02-15)Social mobility describes shifts from one status position to another within a system of social stratification and can either occur within or between generations. Previous research has indicated that mobility between social ... -
Molecular epidemiology of complex heritable disease : applications in genomics and metabolomics
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2012-12-21)Modern high-throughput molecular technologies (collectively referred to as “omic” platforms) are generating unprecedented amounts of data on human variation. The four papers in this thesis each investigate and characterize ...