Licentiatavhandlingar / Licentiate Theses - SwePub: Recent submissions
Now showing items 121-140 of 255
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Sad mothers – disappointed women? Perinatal depression and women's and men's parenthood the first year after childbirth
(Institutionen för kvinnors och barns hälsa / Department of Women's and Children's Health, 2005-09-26)The aim of the present thesis was to study the prevalence of maternal depressive mood during pregnancy and up to one year after childbirth in relation to the parents' psycho-social conditions, perception of the infant's ... -
Modulation of the deubiquitnating system during lymphoid cell activation and viral infection
(Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2005-08-15)The family of ubiquitin-specific proteases (USPs) removes ubiquitin from its conjugates and regulates the production and recycling of ubiquitin. USPs are thereby critically involved in the control of important functions ... -
Chemical transformation of the anticancer drug oxaliplatin
(Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2005-09-02)Oxaliplatin is a new platinum based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin, both as palliative and adjuvant treatment of metastatic colorectal cancer. Various biotransformation products ... -
Quantitative EEG analysis : temporal variability and clinical applications
(Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2005-09-30)The quantification of the EEG power (qEEG) in different frequency bands, and their spatial distribution improve the sensitivity of the technique, although questions have been raised about the reproducibility of the results. ... -
Sarcoplasmic body myopathy
(Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2005-10-13)In 1980 a new hereditary myopathy with adult onset was described in a swedish family. The most characteristic feature of this myopathy was the sarcoplasmic inclusion bodies (SB), seen in the muscle biopsies. Distal muscle ... -
Ante partum determination of lactate in amniotic fluid
(Institutionen Södersjukhuset / Karolinska Institutet, Stockholm Söder Hospital, 2005-05-06)Background: The present studies were conducted to investigate whether lactate determination in vaginal fluids, 'Lac-test', could be used as a diagnostic test for prelabour rupture of membranes (PROM). To derive the best ... -
Diet and ovarian cancer : a population-based cohort of 60 000 women
(Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2005-05-06)Ovarian cancer represents the fourth leading cause of cancer-related mortality among women in Western countries. Hence, identification of risk factors amenable to modification, such as diet, is of considerable public health ... -
Studies of the physiological status of bacteria used for environmental applications
(Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2004-09-06)Today, it is difficult to study the physiological status of inoculants in complex environments, such as soil. In this thesis, we describe the combined use of marker genes and viability stains to determine the physiological ... -
Incidence and prevalence of non-affective psychoses in Stockholm County : a register-based study
(Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2014-11-17)Objective: To estimate the incidence and prevalence of non-affective psychoses including the subgroup schizophrenia in Stockholm County, using health-care records, and to investigate the relationship between psychiatric ... -
Parents’ experiences of nurses’ cultural competence in Swedish paediatric care
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2014-11-11)Due to global migration, Sweden, as is the case for many other countries in Europe, has become a multi-ethnic society. The multi-ethnic composition of the Swedish population has led to an increasing diversity of patients ... -
Atrial fibrillation and its association to cardiac function and structure in cardiovascular disease
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2014-11-03)Aim: To study associations between atrial fibrillation (AF) and echocardiographic measures of left atrial (LA) and left ventricular (LV) parameters in patients with underlying cardiovascular disease. Hypothesis: LA ... -
Structural and biophysical studies of pneumococcal capsular surface proteins
(Inst för medicin, Solna / Dept of Medicine, Solna, 2014-10-15)Streptococcus pneumoniae (pneumococcus) is a major human pathogen and a leading cause of morbidity and mortality worldwide, especially in children and the elderly. The casualties due to respiratory infections are estimated ... -
Immune responses against Mycobacterium tuberculosis targets associated to latent and active tuberculosis infection
(Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2014-09-01)Background: Tuberculosis is a worldwide problem particularly in developing countries. Different clinical outcomes, such as the asymptomatic phase during infection or the symptomatic stage during active disease leads to ... -
Assessment of visual contrast function and effects of citicoline treatment in children with visual impairment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2014-08-29)Purpose: The present studies address the questions if visual dysfunction in severely visually impaired children can be measured with contrast tests high or low, how it relates to their visual abilities assessed with ... -
Flying personnel : cancer, acute myocardial infarction and mortality
(Institutet för miljömedicin / Institute of Environmental Medicine, 2014-05-19)Aim: Flying personnel are exposed to several factors in the work environment that can potentially increase their cancer incidence, mortality and acute myocardial infarction (AMI) incidence. The aim of this licentiate thesis ... -
Molecular mechanisms involved in the generation of calcium signals in insulin secreting cells
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2014-03-14)Intracellular Ca 2+ regulates diverse cellular functions in almost all the cells. In the pancreatic ß-cells, Ca 2+ signals are critical for insulin secretion. An increase in the cytoplasmic free Ca 2+ concentration ([Ca ... -
Renal Klotho in mineral metabolism
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-02-27)Calcium and phosphorous are critical elements in a number of physiological processes, including maintenance of bone structure, cell signaling and energy metabolism. Their endocrine regulation is tightly controlled through ... -
Side-chain oxidized oxysterols as metabolic regulators in liver and brain
(Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2014-02-03)Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion ... -
The expression of the structural proteins dendrin and Neph1 in the glomerular filtration barrier in proteinuria
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-01-22)Background: In the normal kidney, the glomerular filtration barrier successfully clears about one litre blood per minute. Damage to the filtration barrier might lead to protein leakage in the urine – proteinuria. The major ... -
Healthcare providers' perceptions of diversity and cultural competence
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2013-10-28)Swedish society is ethnically diverse and since the early 1960s immigrants have made significant contributions to the labour market in healthcare. Today many Swedes, including first- and second-generation immigrants, work ...