Licentiatavhandlingar / Licentiate Theses - SwePub: Recent submissions

Now showing items 101-120 of 255

    • Induction of type I interferons and viral immunity 

      Hidmark, Åsa (Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2006-01-06)
      Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the ...

    • Molecular epidemiology of hepatitis A, B and C in Estonia 

      Tallo, Tatjana (Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2006-03-31)
      During the last decade changes have occurred in the epidemiology of hepatitis A, B and C in Estonia. A shift from high to intermediate endemicity for HAV has led to a shift in age of susceptible individuals from children ...

    • HHV-8/KSHV association with tumor cells during development of Kaposi sarcoma 

      Pak, Fatemeh (Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2006-01-12)
      Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion which usually presents as a cutaneous disease and progresses to extracutaneous, systemic spread usually in the gastrointestinal (GI) tract, ...

    • The ABC of the cell cycle : roles of the mammalian Cdc25 isoforms 

      Lundgren, Andreas (Institutionen för cell- och molekylärbiologi (CMB) / Department of Cell and Molecular Biology, 2006-02-03)
      Cell cycle progression is mediated by Cyclin dependent kinases (Cdks) in complex with Cyclins. The activity of the Cyclin-Cdk complexes is regulated through a variety of levels: expression and proteolysis of Cyclins, binding ...

    • A study of lymphocyte functions in multiple myelopma 

      Ostad, Masih (Institutionen för medicin / Department of Medicine, 2006-02-07)
      Multiple myeloma (MM) is a lymphoproliferative disorder which is characterized by an accumulation of clonotypic plasma, cells in the bone marrow leading to an overproduction of monoclonal immunoglobulin (mIg). The disease ...

    • Characterization of Eae4 and Eae19-22 in autoimmune neuroinflammation 

      Nohra, Rita (Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2006-02-17)
      Multiple Sclerosis (MS) is the most common chronic inflammatory disorders of the central nervous system (CNS) with a prevalence of 1-211000 in the Northern European population. MS is caused by a combination of environmental ...

    • Pulmonary tuberculosis in pre-trial detentions in St. Petersburg, Russia 

      Lobacheva, Tatiana (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2006-01-06)
      During the last 15 years situation with Tuberculosis (TB) in prison system in Russia has been worsened as well as in the whole country. High TB rates in prison system reflect not only bad conditions there, but also the ...

    • Immunotherapy in cancer and HIV 

      Johansson, Susanne (Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2006-01-31)
      Two major threats to human health are cancer and human immunodeficiency virus (HIV) infection. In both cases, a feature of progress of the disease is a defective immune function. Immunological mechanisms have evolved whereby ...

    • Epstein-Barr virus latency in transplant patients and healthy carriers 

      Zou, Jie-Zhi (Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2005-11-24)
      In this thesis, I studied the latency situation of Epstein-Barr virus (EBV) in bone marrow transplanted (BMT) patients and healthy virus carriers. Paper 1: Epstein-Barr virus genomes are found predominantly in ...

    • Investigations or perimetry and gaze-stability in healthy and deceased retina 

      Källmark, Fredrik (Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2005-11-30)
      Our visual world is composed of images of colours, textures, edges and contrasts. In addition, these images may be moving or flickering. The goal of visual testing is to quantify these functions. Traditionally we have ...

    • Individualized leukapheresis of hematopoietic cells for cellular therapies 

      Mårtensson, Anna (Institutionen för medicin / Department of Medicine, 2005-11-24)
      Hematopoietic stem and progenitor cells from blood (HSC) are collected by leukapheresis from patients after mobilization with G-CSF +/- chemotherapy to be used in autologous transplantation. The established method to measure ...

    • Cataract from ultraviolet radiation in the mouse 

      Meyer, Linda Maren (Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2005-11-25)
      Cataract is defined as an opacification of the crystalline lens that results in visual impairment, Cataract is the number one cause of blindness in the world and there are currently no strategies to prevent it. Extraction ...

    • Evaluation of the infrared reflection method for saccadic eye movement velocity analysis 

      Träisk, Frank (Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2005-12-29)
      Saccades are rapid eye movements that change the orientation of the eyes onto objects of interest. In an every day situation saccadic eye movements are used for e.g. reading, scanning objects and enviromnents. The ...

    • Epidemiological and immunological studies of the hepatitis B virus surface antigen (HBsAg) 

      Björnsdóttir, Thora Björg (Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2006-01-06)

    • Vaccination against drug-resistant HIV 

      Boberg, Andreas (Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2005-11-24)
      As the use of antiretroviral drug treatment increases worldwide, development of drug resistant HIV phenotypes is expected to increase. The frequency of drug- or multi-drug resistant virus transmitted in primary infections ...

    • Five-year follow-up of a randomized controlled trial of early supported discharge and continued rehabilitation at home after stroke 

      Thorsén, Ann-Mari (Institutionen för klinisk neurovetenskap, arbetsterapi och äldrevårdsforskning (NEUROTEC) / Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC), 2005-11-23)
      Introduction: Stroke constitutes the second leading cause of death and the leading determinant of disability among the world population. Stroke is the single physiological condition that requires the most bed-days in Swedish ...

    • Icodextrin metabolism in peritoneal dialysis : clinical and experimental studies 

      García López, Elvia (Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2005-08-31)
      Icodextrin (ICO, or polyglucose) is an effective osmotic agent for peritoneal dialysis (PD) patients (pts). ICO is a soluble polymeric form of glucose with an average molecular 'weight range from 13,000 to 19,000 dalton. ...

    • Analysis of HIF-1alpha degradation and function 

      André, Helder (Institutionen för cell- och molekylärbiologi (CMB) / Department of Cell and Molecular Biology, 2005-11-18)
      HIF-1 is a heterodimeric complex of two bHLH/PAS transcription factors, HIF- 1alpha and ANRT. In contrast to the constitutively expressed ARNT, HIF-1alpha protein levels are regulated by oxygen tension. Under normoxic ...

    • Studies on the regulatory role of cholic acid in cholesterol metabolism 

      Murphy, Charlotte (Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2005-09-14)
      Cholesterol is essential for normal growth and development in both man and mouse. However, excess cholesterol can be harmful leading to diseases such as atherosclerosis and gallstones. Once formed cholesterol cannot be ...

    • Mechanisms on HIV-1 core assembly 

      Abdurahman, Samir (Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2005-11-01)