Now showing items 101-120 of 154

    • Sexual offending runs in families : a 37-year nationwide study 

      Långström, Niklas; Babchishin, Kelly M; Fazel, Seena; Lichtenstein, Paul; Frisell, Thomas (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      BACKGROUND: Sexual crime is an important public health concern. The possible causes of sexual aggression, however, remain uncertain. METHODS: We examined familial aggregation and the contribution of genetic and ...
    • Colorectal cancer prognosis following obesity surgery in a population-based cohort study 

      Tao, Wenjing; Konings, Peter; Hull, Mark A; Adami, Hans-Olov; Mattsson, Fredrik; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-28)
      BACKGROUND: Obesity surgery involves mechanical and physiological changes of the gastrointestinal tract that might promote colorectal cancer progression. Thus, we hypothesised that obesity surgery is associated with poorer ...
    • Risks of psychiatric disorders and suicide attempts in children and adolescents with type 1 diabetes : a population-based cohort study 

      Butwicka, Agnieszka; Frisén, Louise; Almqvist, Catarina; Zethelius, Björn; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-04-28)
      Objective: To assess the risk of psychiatric disorders and suicide attempts in children with type 1 diabetes and their healthy siblings. Research Design and Methods: We performed a population-based case cohort study ...
    • Impact of asthma medication and familial factors on the association between childhood asthma and attention-defict/hyperactivity disorder : a combined twin- and register-based study 

      Holmberg, Kirsten; Lundholm, Cecilia; Anckarsäter, Henrik; Larsson, Henrik; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-04-26)
      BACKGROUND: Asthma and attention-deficit/hyperactivity disorder (ADHD) are prevalent in childhood and may cause functional impairment and stress in families. Previous research supports an association between asthma and ...
    • Further investigations of the relation between polymorphisms in sex steroid related genes and autistic-like traits 

      Zettergren, Anna; Karlsson, Sara; Hovey, Daniel; Jonsson, Lina; Melke, Jonas; Anckarsäter, Henrik; Lichtenstein, Paul; Lundström, Sebastian; Westberg, Lars (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-21)
      Autism spectrum disorders (ASDs) are more prevalent in boys than in girls, indicating that high levels of testosterone during early development may be a risk factor. Evidence for this hypothesis comes from studies showing ...
    • Familial risks of Tourette syndrome and chronic tic disorders : a population-based cohort study 

      Mataix-Cols, David; Isomura, Kayoko; Pérez-Vigil, Ana; Chang, Zheng; Rück, Christian; Larsson, K Johan; Leckman, James F; Serlachius, Eva; Larsson, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-17)
      Importance: Chronic Tic Disorders (CTD), including Tourette Syndrome (TS), are assumed to be strongly familial and heritable. While gene-searching efforts are well underway, precise estimates of familial risk and heritability ...
    • Heritability and confirmation of genetic association studies for childhood asthma in twins. 

      Ullemar, Vilhelmina; Magnusson, Patrik K E; Lundholm, Cecilia; Zettergren, Anna; Melén, Erik; Lichtenstein, Paul; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-17)
      BACKGROUND: Although the genetics of asthma has been extensively studied using both quantitative and molecular genetic analysis methods, both approaches lack studies specific to the childhood phenotype and including other ...
    • Common psychiatric disorders share the same genetic origin : a multivariate sibling study of the Swedish population 

      Pettersson, Erik; Larsson, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-15)
      Recent studies have shown that different mental-health problems appear to be partly influenced by the same set of genes, which can be summarized by a general genetic factor. To date, such studies have relied on surveys of ...
    • Heritability of perinatal depression and genetic overlap with nonperinatal depression 

      Viktorin, Alexander; Meltzer-Brody, Samantha; Kuja-Halkola, Ralf; Sullivan, Patrick F; Landén, Mikael; Lichtenstein, Paul; Magnusson, Patrik K E (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-15)
      OBJECTIVE: The authors investigated the relative importance of genetic and environmental influences on perinatal depression, and the genetic overlap between perinatal depression and nonperinatal depression. METHOD: ...
    • Longitudinal stability of genetic and environmental influences on irritability : from childhood to young adulthood 

      Roberson-Nay, Roxann; Leibenluft, Ellen; Brotman, Melissa A; Myers, John; Lichtenstein, Paul; Kendler, Kenneth S (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-10)
      OBJECTIVE: Little is known about genetic influences on juvenile irritability and whether such influences are developmentally stable and/or dynamic. This study examined the temporal pattern of genetic and environmental ...
    • Depression and violence : a Swedish population study 

      Fazel, Seena; Wolf, Achim; Chang, Zheng; Larsson, Henrik; Goodwin, Guy (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-10)
      BACKGROUND: Depression increases the risk of a range of adverse outcomes including suicide, premature mortality, and self-harm, but associations with violent crime remain uncertain. We aimed to determine the risks of violent ...
    • Childhood neurodevelopmental problems and adolescent bully victimization : population-based, prospective twin study in Sweden 

      Törn, Peggy; Pettersson, Erik; Lichtenstein, Paul; Anckarsäter, Henrik; Lundström, Sebastian; Hellner Gumpert, Clara; Larsson, Henrik; Kollberg, Linnea; Långström, Niklas; Halldner, Linda (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-10)
      Bully victimization is a common problem among children with neurodevelopmental disorders, including attention deficit/hyperactivity disorder and autism spectrum disorder. Previous research was mostly cross-sectional and ...
    • Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10 

      Jonsson, Lina; Zettergren, Anna; Pettersson, Erik; Hovey, Daniel; Anckarsäter, Henrik; Westberg, Lars; Lichtenstein, Paul; Lundström, Sebastian; Melke, Jonas (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-10)
      Background: Autistic-like traits (ALTs) are continuously distributed in the general population, with the autism spectrum disorder (ASD) at the upper extreme end. A genetic overlap has been shown between ALTs and ASD, ...
    • Codevelopment of ADHD and externalizing behavior from childhood to adulthood 

      Kuja-Halkola, Ralf; Lichtenstein, Paul; D'Onofrio, Brian M; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-02)
      BACKGROUND: Attention-Deficit/Hyperactivity Disorder (ADHD) frequently co-occurs with externalizing disorders, but a clear understanding of the etiologic underpinnings is hampered by the limited understanding of the ...
    • A longitudinal study of resting heart rate and violent criminality in more than 700 000 men 

      Latvala, Antti; Kuja-Halkola, Ralf; Almqvist, Catarina; Larsson, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-02)
      IMPORTANCE: Low resting heart rate is a well-replicated physiological correlate of aggressive and antisocial behavior in children and adolescents, but whether low resting heart rate increases the risk of violence and other ...
    • Attention-deficit/hyperactivity disorder and risk for substance use disorders in relatives 

      Skoglund, Charlotte; Chen, Qi; Franck, Johan; Lichtenstein, Paul; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-01)
      BACKGROUND: Previous research indicates that attention-deficit/hyperactivity disorder (ADHD) is highly associated with substance use disorders (SUD). However, these studies have failed to clarify the nature of the overlap. ...
    • Improving risk assessment in schizophrenia : epidemiological investigation of criminal history factors 

      Witt, Katrina; Lichtenstein, Paul; Fazel, Seena (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-01)
      BACKGROUND: Violence risk assessment in schizophrenia relies heavily on criminal history factors. AIMS: To investigate which criminal history factors are most strongly associated with violent crime in schizophreni ...
    • Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study 

      Lundström, Sebastian; Reichenberg, Abraham; Melke, Jonas; Råstam, Maria; Kerekes, Nora; Lichtenstein, Paul; Gillberg, Christopher; Anckarsäter, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-02-26)
      Introduction: Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ...
    • Paternal antisocial behavior and sons' cognitive ability : a population-based quasiexperimental study 

      Latvala, Antti; Kuja-Halkola, Ralf; Långström, Niklas; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-02-23)
      Parents’ antisocial behavior is associated with developmental risks for the offspring but effects on cognitive ability are unknown. We used linked Swedish register data for a large sample of adolescent men (N = 1,177,173) ...
    • Antisocial behavior and polymorphisms in the oxytocin receptor gene : findings in two independent samples 

      Hovey, Daniel; Lindstedt, Måns; Zettergren, Anna; Jonsson, Lina; Johansson, Ada; Melke, Jonas; Kerekes, Nora; Anckarsäter, Henrik; Lichtenstein, Paul; Lundström, Sebastian; Westberg, Lars (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-02-19)
      Importance: The quantitative genetic contribution to antisocial behavior is well established, but few, if any, genetic variants are established as risk factors. Emerging evidence suggests that the neuropeptide oxytocin may ...