Now showing items 121-140 of 154

    • Gastroesophageal reflux does not alter effects of body mass index on risk of esophageal adenocarcinoma 

      Lagergren, Jesper; Mattsson, Fredrik; Nyrén, Olof (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-10-02)
      Background & Aims: A history of high body mass index (BMI) is strongly associated with risk of esophageal adenocarcinoma (EAC). We investigated whether gastroesophageal reflux is involved in this association. Methods: ...
    • Psychotic experiences as a predictor of the natural course of suicidal ideation : a Swedish cohort study 

      Kelleher, Ian; Cederlöf, Martin; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2015-07-21)
      Psychotic experiences are far more prevalent in the population than psychotic disorders and are associated with a wide range of depressive, anxiety and behavioral disorders, as well as increased risk for psychotic disorder. ...
    • Breastfeeding, asthma, and allergy : a tale of two cities 

      Brew, Bronwyn K; Kull, Inger; Garden, Frances L; Almqvist, Catarina; Bergström, Anna; Lind, Tomas; Webb, Karen L; Wickman, Magnus; Marks, Guy B (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2015-07-21)
      BACKGROUND: The effect of breastfeeding duration on subsequent asthma and allergy remains the subject of much controversy. OBJECTIVE: To investigate whether differences in study design or disease-related exposure ...
    • Childhood family income, adolescent violent criminality and substance misuse : a quasi-experimental total population study 

      Sariaslan, Amir; Larsson, Henrik; D'Onofrio, Brian M; Långström, Niklas; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-08-27)
      Background: Low socioeconomic status in childhood is a well-known predictor of subsequent criminal and substance misuse behaviors but the causal mechanisms are questioned. Aims: To investigate if the associations ...
    • The risk of switch to mania in patients with bipolar disorder during treatment with antidepressants alone and in combination with a mood stabilizer 

      Viktorin, Alexander; Lichtenstein, Paul; Thase, Michael E; Larsson, Henrik; Lundholm, Cecilia; Magnusson, Patrik K E; Landén, Mikael (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-08-22)
      Objective: This study examined the risk of antidepressant-induced manic switch in patients with bipolar disorder treated either with antidepressant monotherapy or with an antidepressant in conjunction with a mood ...
    • Familial confounding of the association between maternal smoking during pregnancy and ADHD in offspring 

      Skoglund, Charlotte; Chen, Qi; D'Onofrio, Brian M; Lichtenstein, Paul; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-08-22)
      Background: Maternal Smoking During Pregnancy (SDP) has consistently been associated with increased risk of attention-deficit/hyperactivity disorder (ADHD) in offspring, but recent studies indicate that this association ...
    • Bipolar disorder and its relation to major psychiatric disorders : a family-based study in the Swedish population 

      Song, Jie; Bergen, Sarah E; Kuja-Halkola, Ralf; Landén, Mikael; Larsson, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-08-18)
      OBJECTIVES: Bipolar disorder (BPD) shares genetic components with other psychiatric disorders; however, uncertainty remains about where in the psychiatric spectra BPD falls. To understand the etiology of BPD, we studied ...
    • Multiple sclerosis and psychiatric disorders : comorbidity and sibling risk in a nationwide Swedish cohort 

      Johansson, Viktoria; Lundholm, Cecilia; Hillert, Jan; Masterman, Thomas; Lichtenstein, Paul; Landén, Mikael; Hultman, Christina M (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-08-04)
      Background: Psychiatric disorders are known to be prevalent in Multiple Sclerosis (MS). Objective: To study comorbidity between MS and bipolar disorder, schizophrenia and depression in a nation-wide cohort and to ...
    • Hypospadias and increased risk for neurodevelopmental disorders 

      Butwicka, Agnieszka; Lichtenstein, Paul; Landén, Mikael; Nordenvall, Anna Skarin; Nordenström, Anna; Nordenskjöld, Agneta; Frisén, Louise (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-07-31)
      BACKGROUND: Hypospadias (aberrant opening of the urethra on the underside of the penis) occurs in 1 per 300 newborn boys. It has been previously unknown whether this common malformation is associated with increased psychiatric ...
    • Birth weight as an independent predictor of ADHD symptoms : a within-twin pair analysis 

      Pettersson, Erik; Sjölander, Arvid; Almqvist, Catarina; Anckarsäter, Henrik; D'Onofrio, Brian M; Lichtenstein, Paul; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-07-31)
      BACKGROUND: Studies have found an association between low birth weight and ADHD, but the nature of this relation is unclear. First, it is uncertain whether birth weight is associated with both of the ADHD dimensions, ...
    • Common etiological factors of attention deficit hyperactivity disorder and suicidal behavior : a population-based study in Sweden 

      Ljung, Therese; Chen, Qi; Lichtenstein, Paul; Larsson, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-30)
      IMPORTANCE: The prevention of suicidal behavior is one of the most important tasks for mental health clinicians. Although a few studies have indicated an increased risk of suicidal behavior among individuals with ...
    • Associations between oxytocin-related genes and autistic-like traits 

      Johansson, Daniel; Zettergren, Anna; Jonsson, Lina; Melke, Jonas; Anckarsäter, Henrik; Lichtenstein, Paul; Westberg, Lars (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-30)
      Oxytocin has repeatedly been shown to influence human behavior in social contexts; also, a relationship between oxytocin and the pathophysiology of autism spectrum disorder (ASD) has been suggested. In the present study, ...
    • The association between schizophrenia and rheumatoid arthritis : a nationwide population-based Swedish study on intra-individual and familial risks 

      Sellgren, Carl; Frisell, Thomas; Lichtenstein, Paul; Landén, Mikael; Askling, Johan (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-27)
      Numerous studies have reported a reduced risk of rheumatoid arthritis (RA) in schizophrenia. The mechanisms are unknown, but recent genome-wide association studies of schizophrenia have shown strong associations with markers ...
    • Motor function and perception in children with neuropsychiatric and conduct problems : results from a population based twin study 

      Gustafsson, Peik; Kerekes, Nora; Anckarsäter, Henrik; Lichtenstein, Paul; Gillberg, Christopher; Råstam, Maria (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-27)
      BACKGROUND: Children with early symptomatic psychiatric disorders such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) have been found to have high rates of motor and/or perception ...
    • The roots of autism and ADHD twin study in Sweden (RATSS) 

      Bölte, Sven; Willfors, Charlotte; Berggren, Steve; Norberg, Joakim; Poltrago, Lina; Mevel, Katell; Coco, Christina; Fransson, Peter; Borg, Jacqueline; Rouslan, Sitnikov; Toro, Roberto; Tammimies, Kristiina; Anderlid, Britt-Marie; Nordgren, Ann; Falk, Anna; Meyer, Urs; Kere, Juha; Landén, Mikael; Dalman, Christina; Ronald, Angelica; Anckarsäter, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-25)
      Neurodevelopmental disorders affect a substantial minority of the general population. Their origins are still largely unknown, but a complex interplay of genetic and environmental factors causing disturbances of the central ...
    • Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms 

      Cederlöf, Martin; Östberg, Per; Pettersson, Erik; Anckarsäter, Henrik; Hellner Gumpert, Clara; Lundström, Sebastian; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-25)
      BACKGROUND: Psychotic-like experiences (PLEs) and juvenile mania in adolescence index risk for severe psychopathology in adulthood. The importance of childhood problems with communication, reading, speech and mathematics ...
    • Accounting for genetic and environmental confounds in associations between parent and child characteristics : a systematic review of children-of-twins studies 

      McAdams, Tom A; Neiderhiser, Jenae M; Rijsdijk, Fruhling V; Narusyte, Jurgita; Lichtenstein, Paul; Eley, Thalia C (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-24)
      Parental psychopathology, parenting style, and the quality of intrafamilial relationships are all associated with child mental health outcomes. However, most research can say little about the causal pathways underlying ...
    • On the role of non-shared environment for executive functioning in ADHD : a twin-differences design study 

      Willfors, Charlotte; Ronald, Angelica; Berggren, Steve; Lichtenstein, Paul; Anckarsäter, Henrik; Coco, Christina; Bölte, Sven (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-24)
      Introduction: The study of differences between monozygotic (MZ) twin pairs with respect to ADHD may provide novel leads to disentangle the environmental contribution driving its phenotypes. Objectives: To examine ...
    • Suboptimal psychosocial outcomes in patients with congenital adrenal hyperplasia : epidemiological studies in a nonbiased national cohort in Sweden 

      Strandqvist, Anna; Falhammar, Henrik; Lichtenstein, Paul; Hirschberg, Angelica L; Wedell, Anna; Norrby, Christina; Nordenskjöld, Agneta; Frisén, Louise; Nordenström, Anna (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-13)
      Context: Congenital adrenal hyperplasia (CAH), CYP21A2 deficiency, results in cortisol and aldosterone deficiency and increased production of androgens, with a good genotype phenotype correlation. Objective: To study ...
    • Relative immaturity and ADHD : findings from nationwide registers, parent- and self-reports 

      Halldner, Linda; Tillander, Annika; Lundholm, Cecilia; Boman, Marcus; Långström, Niklas; Larsson, Henrik; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-05-20)
      BACKGROUND: We addressed if immaturity relative to peers reflected in birth month increases the likelihood of ADHD diagnosis and treatment. METHODS: We linked nationwide Patient and Prescribed Drug Registers and ...