Artiklar / Articles - C8 (MEB): Recent submissions

Now showing items 81-100 of 154

    • The influence of childhood asthma on puberty and height in Swedish adolescents 

      Protudjer, Jennifer; Lundholm, Cecilia; Bergström, Anna; Kull, Inger; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      BACKGROUND: Evidence relating to the effect of asthma on puberty or height is inconclusive. We aimed to examine whether the exposure of childhood asthma, including timing and phenotypes, and inhaled corticosteroid (ICS) ...

    • Determining breast cancer histological grade from RNA-sequencing data 

      Wang, Mei; Klevebring, Daniel; Lindberg, Johan; Czene, Kamila; Grönberg, Henrik; Rantalainen, Mattias (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      BACKGROUND: The histologic grade (HG) of breast cancer is an established prognostic factor. The grade is usually reported on a scale ranging from 1 to 3, where grade 3 tumours are the most aggressive. However, grade 2 is ...

    • Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers 

      Rantalainen, Mattias; Klevebring, Daniel; Lindberg, Johan; Ivansson, Emma; Rosin, Gustaf; Kis, Lorand; Celebiouglu, Fuat; Fredriksson, Irma; Czene, Kamila; Frisell, Jan; Hartman, Johan; Bergh, Jonas; Grönberg, Henrik (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      Sequencing-based breast cancer diagnostics have the potential to replace routine biomarkers and provide molecular characterization that enable personalized precision medicine. Here we investigate the concordance between ...

    • Study design requirements for RNA sequencing-based breast cancer diagnostics 

      Mer, Arvind Singh; Klevebring, Daniel; Grönberg, Henrik; Rantalainen, Mattias (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      Sequencing-based molecular characterization of tumors provides information required for individualized cancer treatment. There are well-defined molecular subtypes of breast cancer that provide improved prognostication ...

    • Early exposure to dogs and farm animals and the risk of childhood asthma 

      Fall, Tove; Lundholm, Cecilia; Örtqvist, Anne K; Fall, Katja; Fang, Fang; Hedhammar, Åke; Kämpe, Olle; Ingelsson, Erik; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      IMPORTANCE: The association between early exposure to animals and childhood asthma is not clear, and previous studies have yielded contradictory results. OBJECTIVE: To determine whether exposure to dogs and farm ...

    • The observed association between maternal anxiety and adolescent asthma : children of twin design suggest familial effects 

      Havland, Ida; Lundholm, Cecilia; Lichtenstein, Paul; Neiderhiser, Jenae M; Ganiban, Jody M; Spotts, Erica L; Walum, Hasse; Reiss, David; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      BACKGROUND: Previous studies indicate that maternal anxiety is associated with asthma in the adolescent child, but mechanisms are unclear. OBJECTIVE: To investigate the association between maternal anxiety and ...

    • Asthma during pregnancy in a population-based study : pregnancy complications and adverse perinatal outcomes 

      Rejnö, Gustaf; Lundholm, Cecilia; Gong, Tong; Larsson, Kjell; Saltvedt, Sissel; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      BACKGROUND: Asthma is one of the most common chronic diseases, and prevalence, severity and medication may have an effect on pregnancy. We examined maternal asthma, asthma severity and control in relation to ...

    • Parental socioeconomic status, childhood asthma and medication use : a population-based study 

      Gong, Tong; Lundholm, Cecilia; Rejnö, Gustaf; Mood, Carina; Långström, Niklas; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      BACKGROUND: Little is known about how parental socioeconomic status affects offspring asthma risk in the general population, or its relation to healthcare and medication use among diagnosed children. METHODS: This ...

    • Antibiotics in fetal and early life and subsequent childhood asthma : nationwide population based study with sibling analysis 

      Örtqvist, Anne K; Lundholm, Cecilia; Kieler, Helle; Ludvigsson, Jonas F; Fall, Tove; Ye, Weimin; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      Erratum to this article in BMJ. 2014;349:g7395. OBJECTIVE: To investigate the association between exposure to antibiotics in fetal and early life and asthma in childhood, with adjustment for confounding factors. ...

    • Antibiotic treatment and length of hospital stay in relation to delivery mode and prematurity 

      Ahlén, Katia M; Örtqvist, Anne K; Gong, Tong; Wallas, Alva K; Ye, Weimin; Lundholm, Cecilia; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      AIM: To investigate how 1) maternal delivery mode and 2) prematurity in infants are associated to antibiotic treatment and length of hospital stay. METHODS: Women having given birth and infants 0-12 months discharged ...

    • Psychiatric disorders and suicide attempts in Swedish survivors of the 2004 southeast Asia tsunami : a 5 year matched cohort study 

      Arnberg, Filip; Gudmundsdóttir, Ragnhildur; Butwicka, Agnieszka; Fang, Fang; Lichtenstein, Paul; Hultman, Christina M; Valdimarsdóttir, Unnur (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-19)
      BACKGROUND: Survivors of natural disasters are thought to be at an increased risk of psychiatric disorders, however the extent of this risk, and whether it is linked to pre-existing psychopathology, is not known. We aimed ...

    • Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age 

      Viktorin, Alexander; Lichtenstein, Paul; Lundholm, Cecilia; Almqvist, Catarina; D'Onofrio, Brian M; Larsson, Henrik; Landén, Mikael; Magnusson, Patrik K E (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-19)
      BACKGROUND: Depression around the time of pregnancy affects at least 1 in 8 women and treatment with selective serotonin re-uptake inhibitors (SSRIs) in pregnant women has been increasing, but research on adverse effects ...

    • Exome sequencing of contralateral breast cancer identifies metastatic disease 

      Klevebring, Daniel; Lindberg, Johan; Rockberg, Julia; Hilliges, Camilla; Hall, Per; Sandberg, Maria; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-05)
      Women with contralateral breast cancer (CBC) have significantly worse prognosis compared to women with unilateral cancer. A possible explanation of the poor prognosis of patients with CBC is that in a subset of patients, ...

    • Differences in survival for patients with familial and sporadic cancer 

      Lee, Myeongjee; Reilly, Marie; Lindström, Linda Sofie; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-05)
      Family history of cancer is a well-known risk factor but the role of family history in survival is less clear. The aim of this study was to investigate the association between family history and cancer survival for the ...

    • Risk of hospitalization and death due to bone fractures after breast cancer: a registry-based cohort study 

      Colzani, Edoardo; Clements, Mark; Johansson, Anna L V; Liljegren, Annelie; He, Wei; Brand, Judith S; Adolfsson, Jan; Fornander, Tommy; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-01)
      BACKGROUND: Bone fractures may have an impact on prognosis of breast cancer. The long-term risks of bone fracture in breast cancer patients have not been thoroughly studied. METHODS: Poisson regression was used to ...

    • Cause-specific mortality in women with breast cancer in situ 

      He, Wei; Lindström, Linda Sofie; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      The long-term mortality remains unknown in women diagnosed with breast cancer in situ (BCIS). Here, we assessed the cause-specific mortality in BCIS patients. This population-based cohort study included 12,243 women diagnosed ...

    • Time-dependent risk and predictors of venous thromboembolism in breast cancer patients: a population-based cohort study 

      Brand, Judith S; Hedayati, Elham; Bhoo-Pathy, Nirmala; Bergh, Jonas; Hall, Per; Humphreys, Keith; Ludvigsson, Jonas F; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      BACKGROUND: Venous thromboembolism (VTE) is a serious complication of cancer and its treatment. The current study assessed the risk and clinical predictors of VTE in breast cancer patients by time since diagnosis. METHODS: ...

    • Predictors for discontinuation of adjuvant hormone therapy in breast cancer patients 

      He, Wei; Fang, Fang; Varnum, Catherine; Eriksson, Mikael; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      PURPOSE: To identify predictors of discontinuation of adjuvant hormone therapy in patients with breast cancer. PATIENTS AND METHODS: We conducted a record-linkage study based on data from Stockholm-Gotland Breast ...

    • Infection-related hospitalizations in breast cancer patients : risk and impact on prognosis 

      Brand, Judith S; Colzani, Edoardo; Johansson, Anna L V; Giesecke, Johan; Clements, Mark; Bergh, Jonas; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      OBJECTIVES: Infections are a common cause of hospitalization in breast cancer patients. We studied the risk, clinical characteristics and outcomes of infection-related hospitalizations in this patient population. METHODS: ...

    • Longitudinal fluctuation in mammographic percent density differentiates between interval and screen-detected breast cancer 

      Strand, Fredrik; Humphreys, Keith; Eriksson, Mikael; Li, Jingmei; Andersson, Therese M L; Törnberg, Sven; Azavedo, Edward; Shepherd, John; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)
      Interval breast cancer (IC) has a more aggressive phenotype and higher mortality than screen-detected cancer (SDC). In this case-case study, we investigated whether the size of longitudinal fluctuations in mammographic ...