Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions

Now showing items 61-80 of 529

    • Time resolved functional brain networks : a novel method and developmental perspective 

      Strindberg, Marika (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-28)
      Functional neuroimaging has helped elucidating the complexity of brain function in ever more detail during the last 30 years. In this time the concepts used to understand how the brain works has also developed from a focus ...

    • Register-based studies on childhood cancer : relapsed childhood acute lymphoblastic leukemia and skeletal adverse events in childhood cancer survivors in the Nordic countries 

      Óskarsson, Trausti (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-28)
      Background: Although cancer is a rare disease in children, it is the leading disease-related cause of death in children and adolescents in developed countries. Currently 80% of patients become long-time survivors but if a ...

    • Pre-analytical errors in blood sampling procedures in paediatric hospital care 

      Hjelmgren, Henrik (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-14)
      Introduction: Blood tests are important for diagnosing and treating children who are hospitalised with illnesses. The blood test process follows the specific phases of pre-analysis, analysis and post-analysis. Most blood ...

    • Human myeloid cells in cancer, inflammation, and infection 

      Kvedaraitė, Eglė (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-12-01)
      Myeloid cells are a part of innate immunity, playing a major role in orchestrating innate and adaptive immune responses. While work performed in experiment model systems has significantly increased our knowledge on fundamental ...

    • Physical comorbidity in twins with ASD or ADHD 

      Pan, Pei-Yin (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-12)
      Background: Individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have an increased risk for a range of physical disorders, which can complicate the clinical management, and ...

    • Anticancer drug treatment in pediatric patients : studies on optimizing dosage and on parental guidance for improved drug handling at home 

      Akkawi el Edelbi, Ranaa (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-12)
      Background: Every year about 370 children are diagnosed with cancer in Sweden. The treatment includes both inpatient and outpatient care with anticancer drugs. At the clinic, the optimal anticancer drug dosage is usually ...

    • Hyperinflammation in critically ill 

      Bahr Greenwood, Tatiana von (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-11)
      Background: A wide spectrum of inflammatory responses, with overlapping characteristics, is encountered in critically ill patients in intensive care. At one extreme, critically ill patients may develop the potentially fatal ...

    • Viral respiratory tract infections in children 

      Hamrin, Johan (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-28)
      The most common infection in humans is viral respiratory tract infections which predominantly present as the ‘common cold’. In some circumstances however, respiratory viruses cause acute lower respiratory tract infections ...

    • Cerebral palsy in Uganda : prevalence, mortality, functional development, access to services and wheelchair intervention 

      Andrews, Carin (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-22)
      Background and aim: Cerebral palsy (CP) is one of the most common causes of childhood physical disability, but little is known of children and young people with CP living in low and middle-income countries (LMIC). The ...

    • The role of the microenvironment in growth plate and articular chondrocyte differentiation 

      Dou, Zelong (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-20)
      One crucial process during skeletal development is joint formation. It starts with the interzone appearance characterized by high expression of Gdf5, Gli3, Wnt4 and Wnt9a, low expression of Col2a1 of the local compact ...

    • Effects of insulin on the decidualization of human endometrial stromal cells : in vitro studies 

      Jakson, Ivika (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-01)
      Hyperinsulinemia is a known characteristic of obesity and polycystic ovary syndrome, two common clinical conditions associated with reproductive problems. However, the underlying mechanisms to reduced fertility are not ...

    • Number of siblings and survival from childhood leukaemia : a national register-based cohort study from Sweden 

      Mogensen, Hanna; Modig, Karin; Talbäck, Mats; Erdmann, Friederike; Heyman, Mats; Feychting, Maria; Tettamanti, Giorgio (Institutet för miljömedicin / Institute of Environmental Medicine, 2021-05-31)
      Background: Previous studies suggest worse leukaemia survival for children with siblings, but the evidence is sparse, inconsistent and does not consider clinical factors. We explored the associations between number of ...

    • The preterm infant : evaluating and developing non-invasive respiratory strategies to avoid mechanical ventilation 

      Donaldsson, Snorri F (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-11)
      Avoiding mechanical ventilation of preterm infants is important to prevent morbidity and mortality. Non-invasive ventilation and CPAP has been shown to be superior to intubation and mechanical ventilation in preventing ...

    • Hereditary, molecular and prognostic factors in endometrial cancer 

      Wersäll, Ofra Castro (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-10)
      Aims: The overall aim of this thesis is to describe and evaluate hereditary uterine cancer syndrome both independent of and in relation to hereditary patterns of Lynch and/or Cowden syndrome for the purpose of recognizing ...

    • Adenomyosis : imaging features for diagnosing the disease and treatment effects of bromocriptine 

      Andersson, Johanna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-07)
      Background: Adenomyosis is a benign uterine disease, causing various symptoms including heavy menstrual bleeding (HMB) and pelvic pain. In affected women, endometrial glands and stroma are located in the myometrium surrounded ...

    • Endocrine profile in female Olympic athletes : of importance for physical performance and impact on anti-doping testing 

      Eklund, Emma (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-06)
      Endogenous androgens and insulin-like growth factor-I (IGF-I) are anabolic hormones that may contribute to increased muscle mass and possibly enhanced athletic performance. Furthermore, the second to fourth digit ratio ...

    • Understanding and targeting the architecture in cancer : novel therapies in neuroblastoma and medulloblastoma 

      Andonova, Teodora (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-03-31)
      Cancer is the second leading cause of death worldwide after cardiovascular diseases. In Sweden, childhood cancer is the most common cause of death in children 1-14 years of age. Owing to advances in treatment and a better ...

    • A balancing act : work life and childcare among parents of children with cancer 

      Hjelmstedt, Sofia (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-03-24)
      Aim: The overall aim of this thesis was to investigate the socioeconomic consequences for parents of children with cancer in Sweden. The specific aims were to increase the knowledge of (I) risk of sick leave, (II) division ...

    • Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age 

      Merid, Simon Kebede; Novoloaca, Alexei; Sharp, Gemma C; Küpers, Leanne K; Kho, Alvin T; Roy, Ritu; Gao, Lu; Annesi-Maesano, Isabella; Jain, Pooja; Plusquin, Michelle; Kogevinas, Manolis; Allard, Catherine; Vehmeijer, Florianne O; Kazmi, Nabila; Salas, Lucas A; Rezwan, Faisal I; Zhang, Hongmei; Sebert, Sylvain; Czamara, Darina; Rifas-Shiman, Sheryl L; Melton, Phillip E; Lawlor, Debbie A; Pershagen, Göran; Breton, Carrie V; Huen, Karen; Baiz, Nour; Gagliardi, Luigi; Nawrot, Tim S; Corpeleijn, Eva; Perron, Patrice; Duijts, Liesbeth; Nohr, Ellen Aagaard; Bustamante, Mariona; Ewart, Susan L; Karmaus, Wilfried; Zhao, Shanshan; Page, Christian M; Herceg, Zdenko; Jarvelin, Marjo-Riitta; Lahti, Jari; Baccarelli, Andrea A; Anderson, Denise; Kachroo, Priyadarshini; Relton, Caroline L; Bergström, Anna; Eskenazi, Brenda; Soomro, Munawar Hussain; Vineis, Paolo; Snieder, Harold; Bouchard, Luigi; Jaddoe, Vincent W; Sørensen, Thorkild I A; Vrijheid, Martine; Arshad, S Hasan; Holloway, John W; Håberg, Siri E; Magnus, Per; Dwyer, Terence; Binder, Elisabeth B; DeMeo, Dawn L; Vonk, Judith M; Newnham, John; Tantisira, Kelan G; Kull, Inger; Wiemels, Joseph L; Heude, Barbara; Sunyer, Jordi; Nystad, Wenche; Munthe-Kaas, Monica C; Räikkönen, Katri; Oken, Emily; Huang, Rae-Chi; Weiss, Scott T; Antó, Josep Maria; Bousquet, Jean; Kumar, Ashish; Söderhäll, Cilla; Almqvist, Catarina; Cardenas, Andres; Gruzieva, Olena; Xu, Cheng-Jian; Reese, Sarah E; Kere, Juha; Brodin, Petter; Solomon, Olivia; Wielscher, Matthias; Holland, Nina; Ghantous, Akram; Hivert, Marie-France; Felix, Janine F; Koppelman, Gerard H; London, Stephanie J; Melén, Erik (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-03-05)
      Background: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated ...

    • Web-based support for young adults with reproductive concerns following cancer : development, process and outcome evaluation of a self-help psychoeducational intervention 

      Micaux, Claire (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-02-05)
      AIM: To describe the development process and explain the outcomes of Fex-Can Fertility, a self-help web-based psychoeducational intervention aiming to alleviate reproductive concerns in young adults with cancer. METHODS: ...