Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions
Now showing items 61-80 of 536
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Congenital adrenal hyperplasia : pre-and postnatal treatment effects on cognition, behavior and brain resting-state functional connectivity
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-14)Congenital adrenal hyperplasia (CAH), an autosomal recessive disorder affecting adrenal steroid synthesis, is linked to impaired adrenal synthesis of cortisol and aldosterone. The increased production of androgen precursors ... -
Molecular and clinical studies of intestinal malrotation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-13)Intestinal malrotation (IM) can present as a potentially life-threatening condition with midgut volvulus and need of immediate surgery, but also as a chronic condition with long-lasting symptoms. It is a well-known neonatal ... -
Modern contraceptive use among female refugee adolescents in northern Uganda : prevalence, effect of peer counselling, adherence, and experiences
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-11)Background: Adolescent pregnancies have remained high globally, with the highest rates occurring in low- and middle-income countries and humanitarian settings. The high adolescent pregnancy rates have been attributed to ... -
HPV and potential prognostic markers in primary vaginal carcinoma
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-08)The overall aim of this PhD thesis is to evaluate HPV status and immunohistochemical expression of different biomarkers, including tumor suppressor p16, proliferation marker Ki67, molecular markers in the LRIG family, ... -
Neurofeedback and working memory training in children and adolescents with ADHD
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-03-04)Background: ADHD is one of the most prevalent neurodevelopmental disorders among children and adolescents. Although pharmacological interventions are highly effective in attenuating symptoms of inattention and impulsivity, ... -
Endometrial receptivity and regeneration in health and disease : molecular, cellular and clinical perspectives
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-02-25)Each month, the endometrium regenerates under the influence of the ovarian hormones and builds up to a receptive state in preparation for embryo implantation. In the absence of pregnancy, it sheds during menses and the ... -
Genetic implications of individual intervention and neuronal dysfunction in neurodevelopmental disorders
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-02-03)Neurodevelopmental disorders (NDDs) are a group of conditions appearing in childhood, with developmental deficits that produce impairments of functioning. Autism spectrum disorder (ASD) is a common NDD with a high heritability ... -
Time resolved functional brain networks : a novel method and developmental perspective
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-28)Functional neuroimaging has helped elucidating the complexity of brain function in ever more detail during the last 30 years. In this time the concepts used to understand how the brain works has also developed from a focus ... -
Register-based studies on childhood cancer : relapsed childhood acute lymphoblastic leukemia and skeletal adverse events in childhood cancer survivors in the Nordic countries
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-28)Background: Although cancer is a rare disease in children, it is the leading disease-related cause of death in children and adolescents in developed countries. Currently 80% of patients become long-time survivors but if a ... -
Pre-analytical errors in blood sampling procedures in paediatric hospital care
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-01-14)Introduction: Blood tests are important for diagnosing and treating children who are hospitalised with illnesses. The blood test process follows the specific phases of pre-analysis, analysis and post-analysis. Most blood ... -
Human myeloid cells in cancer, inflammation, and infection
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-12-01)Myeloid cells are a part of innate immunity, playing a major role in orchestrating innate and adaptive immune responses. While work performed in experiment model systems has significantly increased our knowledge on fundamental ... -
Physical comorbidity in twins with ASD or ADHD
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-12)Background: Individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have an increased risk for a range of physical disorders, which can complicate the clinical management, and ... -
Anticancer drug treatment in pediatric patients : studies on optimizing dosage and on parental guidance for improved drug handling at home
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-12)Background: Every year about 370 children are diagnosed with cancer in Sweden. The treatment includes both inpatient and outpatient care with anticancer drugs. At the clinic, the optimal anticancer drug dosage is usually ... -
Hyperinflammation in critically ill
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-11-11)Background: A wide spectrum of inflammatory responses, with overlapping characteristics, is encountered in critically ill patients in intensive care. At one extreme, critically ill patients may develop the potentially fatal ... -
Viral respiratory tract infections in children
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-28)The most common infection in humans is viral respiratory tract infections which predominantly present as the ‘common cold’. In some circumstances however, respiratory viruses cause acute lower respiratory tract infections ... -
Cerebral palsy in Uganda : prevalence, mortality, functional development, access to services and wheelchair intervention
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-22)Background and aim: Cerebral palsy (CP) is one of the most common causes of childhood physical disability, but little is known of children and young people with CP living in low and middle-income countries (LMIC). The ... -
The role of the microenvironment in growth plate and articular chondrocyte differentiation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-20)One crucial process during skeletal development is joint formation. It starts with the interzone appearance characterized by high expression of Gdf5, Gli3, Wnt4 and Wnt9a, low expression of Col2a1 of the local compact ... -
Effects of insulin on the decidualization of human endometrial stromal cells : in vitro studies
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-10-01)Hyperinsulinemia is a known characteristic of obesity and polycystic ovary syndrome, two common clinical conditions associated with reproductive problems. However, the underlying mechanisms to reduced fertility are not ... -
Number of siblings and survival from childhood leukaemia : a national register-based cohort study from Sweden
(Institutet för miljömedicin / Institute of Environmental Medicine, 2021-05-31)Background: Previous studies suggest worse leukaemia survival for children with siblings, but the evidence is sparse, inconsistent and does not consider clinical factors. We explored the associations between number of ... -
The preterm infant : evaluating and developing non-invasive respiratory strategies to avoid mechanical ventilation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-11)Avoiding mechanical ventilation of preterm infants is important to prevent morbidity and mortality. Non-invasive ventilation and CPAP has been shown to be superior to intubation and mechanical ventilation in preventing ...