Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions

Now showing items 81-100 of 536

    • Hereditary, molecular and prognostic factors in endometrial cancer 

      Wersäll, Ofra Castro (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-10)
      Aims: The overall aim of this thesis is to describe and evaluate hereditary uterine cancer syndrome both independent of and in relation to hereditary patterns of Lynch and/or Cowden syndrome for the purpose of recognizing ...

    • Adenomyosis : imaging features for diagnosing the disease and treatment effects of bromocriptine 

      Andersson, Johanna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-07)
      Background: Adenomyosis is a benign uterine disease, causing various symptoms including heavy menstrual bleeding (HMB) and pelvic pain. In affected women, endometrial glands and stroma are located in the myometrium surrounded ...

    • Endocrine profile in female Olympic athletes : of importance for physical performance and impact on anti-doping testing 

      Eklund, Emma (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-06)
      Endogenous androgens and insulin-like growth factor-I (IGF-I) are anabolic hormones that may contribute to increased muscle mass and possibly enhanced athletic performance. Furthermore, the second to fourth digit ratio ...

    • Understanding and targeting the architecture in cancer : novel therapies in neuroblastoma and medulloblastoma 

      Andonova, Teodora (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-03-31)
      Cancer is the second leading cause of death worldwide after cardiovascular diseases. In Sweden, childhood cancer is the most common cause of death in children 1-14 years of age. Owing to advances in treatment and a better ...

    • A balancing act : work life and childcare among parents of children with cancer 

      Hjelmstedt, Sofia (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-03-24)
      Aim: The overall aim of this thesis was to investigate the socioeconomic consequences for parents of children with cancer in Sweden. The specific aims were to increase the knowledge of (I) risk of sick leave, (II) division ...

    • Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age 

      Merid, Simon Kebede; Novoloaca, Alexei; Sharp, Gemma C; Küpers, Leanne K; Kho, Alvin T; Roy, Ritu; Gao, Lu; Annesi-Maesano, Isabella; Jain, Pooja; Plusquin, Michelle; Kogevinas, Manolis; Allard, Catherine; Vehmeijer, Florianne O; Kazmi, Nabila; Salas, Lucas A; Rezwan, Faisal I; Zhang, Hongmei; Sebert, Sylvain; Czamara, Darina; Rifas-Shiman, Sheryl L; Melton, Phillip E; Lawlor, Debbie A; Pershagen, Göran; Breton, Carrie V; Huen, Karen; Baiz, Nour; Gagliardi, Luigi; Nawrot, Tim S; Corpeleijn, Eva; Perron, Patrice; Duijts, Liesbeth; Nohr, Ellen Aagaard; Bustamante, Mariona; Ewart, Susan L; Karmaus, Wilfried; Zhao, Shanshan; Page, Christian M; Herceg, Zdenko; Jarvelin, Marjo-Riitta; Lahti, Jari; Baccarelli, Andrea A; Anderson, Denise; Kachroo, Priyadarshini; Relton, Caroline L; Bergström, Anna; Eskenazi, Brenda; Soomro, Munawar Hussain; Vineis, Paolo; Snieder, Harold; Bouchard, Luigi; Jaddoe, Vincent W; Sørensen, Thorkild I A; Vrijheid, Martine; Arshad, S Hasan; Holloway, John W; Håberg, Siri E; Magnus, Per; Dwyer, Terence; Binder, Elisabeth B; DeMeo, Dawn L; Vonk, Judith M; Newnham, John; Tantisira, Kelan G; Kull, Inger; Wiemels, Joseph L; Heude, Barbara; Sunyer, Jordi; Nystad, Wenche; Munthe-Kaas, Monica C; Räikkönen, Katri; Oken, Emily; Huang, Rae-Chi; Weiss, Scott T; Antó, Josep Maria; Bousquet, Jean; Kumar, Ashish; Söderhäll, Cilla; Almqvist, Catarina; Cardenas, Andres; Gruzieva, Olena; Xu, Cheng-Jian; Reese, Sarah E; Kere, Juha; Brodin, Petter; Solomon, Olivia; Wielscher, Matthias; Holland, Nina; Ghantous, Akram; Hivert, Marie-France; Felix, Janine F; Koppelman, Gerard H; London, Stephanie J; Melén, Erik (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-03-05)
      Background: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated ...

    • Web-based support for young adults with reproductive concerns following cancer : development, process and outcome evaluation of a self-help psychoeducational intervention 

      Micaux, Claire (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-02-05)
      AIM: To describe the development process and explain the outcomes of Fex-Can Fertility, a self-help web-based psychoeducational intervention aiming to alleviate reproductive concerns in young adults with cancer. METHODS: ...

    • The effect of a progesterone receptor modulator on the endometrium and breast in premenopausal women 

      Papaikonomou, Kiriaki (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-01-28)
      Background: The levonorgestrel intrauterine system, LNG-IUS 52 mg, is a highly effective and cost-effective contraceptive, entailing minimal patient effort. Irregular bleeding patterns are common during the first months ...

    • Effect of shock wave therapy on longitudinal bone growth and growth plate cartilage 

      Ramesh, Sowmya (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-12-30)
      Aim: The overall aim of this thesis was to investigate the potential for radial shock wave treatment (rSWT) to regulate growth plate chondrogenesis and longitudinal bone growth. It was based on the hypothesis that the ...

    • Coeliac disease in children and adolescents with type 1 diabetes : screening, diagnosis and prevalence 

      Cerqueiro Bybrant, Mara (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-26)
      Background: Coeliac disease (CD) is more common in children and adolescents with type 1 diabetes (T1D). Both diseases share the same high-risk genes: human leukocyte antigen (HLA) DQ2 and DQ8. Other factors than gluten ...

    • Epidemiology and clinical characteristics of paediatric bloodstream infections 1998-2018 in Stockholm 

      Luthander, Joachim (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-17)
      Bloodstream infections (BSI) constitute a common, serious, and potentially preventable cause of morbidity and mortality in children. Good knowledge of epidemiology, aetiology and the occurrence of antimicrobial resistance ...

    • Abortion, contraception and associated social stigma : consequences and solutions in a low-resource setting in western Kenya 

      Rehnström Loi, Ulrika (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-11)
      Background: Complications of unsafe abortion is one of the top causes of maternal morbidity and mortality among women and adolescent girls globally. Stigmatising attitudes and behaviour seem to directly impact women’s and ...

    • Metabolic and cognitive effects after early prenatal dexamethasone treatment 

      Wallensteen, Lena (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-11)
      Congenital adrenal hyperplasia (CAH), due to 21-hydroxylase deficiency (21OHD), is a disease with an inborn error of the adrenal steroid synthesis. This enzyme deficiency leads to cortisol shortage and androgen excess. If ...

    • Oncologic and functional outcomes after robot-assisted radical hysterectomy for cervical cancer 

      Wallin, Emelie (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-16)
      Background: Cervical cancer is the fourth most common cancer in women worldwide, but the incidence has rapidly declined in developed countries after the introduction of structured screening programs. This disease is caused ...

    • Neonatal hypoxic ischemic encephalopathy : inflammation and therapies 

      Di Martino, Elena (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-02)
      Neonatal hypoxic ischemia (HI) is a severe condition characterized by a complex pathophysiology. The lack of oxygen (hypoxia) and blood flow (ischemia) leads to neuronal cell death via necrosis and apoptosis, and a consequent ...

    • Cerebral palsy : studies on health and social outcomes in young adulthood, and on treatments for spasticity and pain 

      Jacobson, Dan (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-01)
      Cerebral palsy (CP) is a permanent disorder caused by a non-progressive brain injury or malformation that has occurred early in the development of the child’s brain. The disorder is characterized by dysfunction of movement ...

    • Endometrial regeneration : unraveling the mysteries of the stroma 

      Queckbörner, Suzanna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-27)
      The healthy endometrium has the unique capacity of shedding and regenerating its functional layer once every menstrual cycle, under the regulation of hormones, progenitor cell populations and inflammatory mediators. Thanks ...

    • Ovarian response to vascular and toxic insults in early life : focus on ovarian reserve and fertility preservation 

      Pampanini, Valentina (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-08)
      The ovarian reserve is defined as the number of eggs embodied in primordial follicles. Every woman is born with a fixed number of primordial follicles, which are formed during fetal development. Pathological events can ...

    • New light on neurocognitive processes linked to autism and attention deficit and hyperactivity disorder in childhood : studies of eye movements in twins 

      Siqueiros Sanchez, Monica (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-08)
      Visual attention and oculomotor response inhibition have been associated with Autism Spectrum Disorder (ASD) and Attention Deficit and Hyperactivity Disorder (ADHD) respectively. The aim of this thesis was to increase our ...

    • Measurement instruments for the early detection of unilateral cerebral palsy and evaluation of bimanual performance 

      Ryll, Ulrike Claudia (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-04-24)
      Infants with early brain lesions are at risk of developing unilateral cerebral palsy (CP) and valid and reliable measurement instruments for their early detection as well as evaluation of their bimanual performance at later ...