Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions
Now showing items 81-100 of 532
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A balancing act : work life and childcare among parents of children with cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-03-24)Aim: The overall aim of this thesis was to investigate the socioeconomic consequences for parents of children with cancer in Sweden. The specific aims were to increase the knowledge of (I) risk of sick leave, (II) division ... -
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-03-05)Background: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated ... -
Web-based support for young adults with reproductive concerns following cancer : development, process and outcome evaluation of a self-help psychoeducational intervention
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-02-05)AIM: To describe the development process and explain the outcomes of Fex-Can Fertility, a self-help web-based psychoeducational intervention aiming to alleviate reproductive concerns in young adults with cancer. METHODS: ... -
The effect of a progesterone receptor modulator on the endometrium and breast in premenopausal women
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-01-28)Background: The levonorgestrel intrauterine system, LNG-IUS 52 mg, is a highly effective and cost-effective contraceptive, entailing minimal patient effort. Irregular bleeding patterns are common during the first months ... -
Effect of shock wave therapy on longitudinal bone growth and growth plate cartilage
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-12-30)Aim: The overall aim of this thesis was to investigate the potential for radial shock wave treatment (rSWT) to regulate growth plate chondrogenesis and longitudinal bone growth. It was based on the hypothesis that the ... -
Coeliac disease in children and adolescents with type 1 diabetes : screening, diagnosis and prevalence
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-26)Background: Coeliac disease (CD) is more common in children and adolescents with type 1 diabetes (T1D). Both diseases share the same high-risk genes: human leukocyte antigen (HLA) DQ2 and DQ8. Other factors than gluten ... -
Epidemiology and clinical characteristics of paediatric bloodstream infections 1998-2018 in Stockholm
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-17)Bloodstream infections (BSI) constitute a common, serious, and potentially preventable cause of morbidity and mortality in children. Good knowledge of epidemiology, aetiology and the occurrence of antimicrobial resistance ... -
Abortion, contraception and associated social stigma : consequences and solutions in a low-resource setting in western Kenya
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-11)Background: Complications of unsafe abortion is one of the top causes of maternal morbidity and mortality among women and adolescent girls globally. Stigmatising attitudes and behaviour seem to directly impact women’s and ... -
Metabolic and cognitive effects after early prenatal dexamethasone treatment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-11-11)Congenital adrenal hyperplasia (CAH), due to 21-hydroxylase deficiency (21OHD), is a disease with an inborn error of the adrenal steroid synthesis. This enzyme deficiency leads to cortisol shortage and androgen excess. If ... -
Oncologic and functional outcomes after robot-assisted radical hysterectomy for cervical cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-16)Background: Cervical cancer is the fourth most common cancer in women worldwide, but the incidence has rapidly declined in developed countries after the introduction of structured screening programs. This disease is caused ... -
Neonatal hypoxic ischemic encephalopathy : inflammation and therapies
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-02)Neonatal hypoxic ischemia (HI) is a severe condition characterized by a complex pathophysiology. The lack of oxygen (hypoxia) and blood flow (ischemia) leads to neuronal cell death via necrosis and apoptosis, and a consequent ... -
Cerebral palsy : studies on health and social outcomes in young adulthood, and on treatments for spasticity and pain
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-10-01)Cerebral palsy (CP) is a permanent disorder caused by a non-progressive brain injury or malformation that has occurred early in the development of the child’s brain. The disorder is characterized by dysfunction of movement ... -
Endometrial regeneration : unraveling the mysteries of the stroma
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-27)The healthy endometrium has the unique capacity of shedding and regenerating its functional layer once every menstrual cycle, under the regulation of hormones, progenitor cell populations and inflammatory mediators. Thanks ... -
Ovarian response to vascular and toxic insults in early life : focus on ovarian reserve and fertility preservation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-08)The ovarian reserve is defined as the number of eggs embodied in primordial follicles. Every woman is born with a fixed number of primordial follicles, which are formed during fetal development. Pathological events can ... -
New light on neurocognitive processes linked to autism and attention deficit and hyperactivity disorder in childhood : studies of eye movements in twins
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-05-08)Visual attention and oculomotor response inhibition have been associated with Autism Spectrum Disorder (ASD) and Attention Deficit and Hyperactivity Disorder (ADHD) respectively. The aim of this thesis was to increase our ... -
Measurement instruments for the early detection of unilateral cerebral palsy and evaluation of bimanual performance
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-04-24)Infants with early brain lesions are at risk of developing unilateral cerebral palsy (CP) and valid and reliable measurement instruments for their early detection as well as evaluation of their bimanual performance at later ... -
Inference of systems-level behaviors in the immune system from single-cell data
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-03-27)Understanding the systems-level behaviours of the immune system requires profiling many parameters of its constituents as well as identifying environmental factors influencing the time evolution of immune response. Recent ... -
Estrogen actions in the growth plate cartilage
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-03-24)Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ... -
Awareness of fetal movements and pregnancy outcomes
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-03-03)Fetal movements are one, among others, of the measurable factors indicating wellbeing of the fetus. Decreased fetal movements are associated with intrauterine growth restriction and stillbirth. Women with experience of ... -
Treating postpartum emotional distress by a short-term psychodynamic infant-parent intervention integrated with child health center care
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2020-02-24)Objective: The thesis had two aims. (1) To qualitatively explore the perspectives of CHC nurses’ (study I) parents’ (II) and psychotherapists’ (III) in receiving/offering SPIPIC (Short-term Psychodynamic Infant-Parent ...