Doktorsavhandlingar / Doctoral Theses - H9 (CLINTEC): Recent submissions

Now showing items 41-60 of 494

    • Long-term outcome after hypothermia-treated hypoxic-ischaemic encephalopathy 

      Robertsson Grossmann, Katarina (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-13)
      Hypoxic-ischaemic encephalopathy (HIE) is a major cause of acquired brain injury in newborn infants. It is a potentially life-threatening condition that leaves survivors at substantial risk of life-long debilitating sequelae ...

    • Clinical use of prognostic markers in head and neck cancer 

      Landin, David (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-12)
      Head and neck cancer (HNC) is a heterogeneous group of tumors where squamous cell carcinoma is the most dominant. In 2020, 1640 new cases of HNC were reported in Sweden which accounted for 2.3% of the total cancer incidence. ...

    • Nutritional status, body composition and diet in older adults with chronic kidney disease 

      Windahl, Karin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-12)
      Kidney disease is a public health problem worldwide. The prevalence of chronic kidney disease (CKD) in Sweden is 6% whereas in people above 75 years of age the prevalence is 28%. Diabetes and hypertension are common causes ...

    • Surgical reconstruction of functional and anatomical defects in the diaphragmatic hiatus 

      Analatos, Apostolos (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-10)
      Gastroesophageal reflux disease (GERD) is characterized mainly by heartburn and acid regurgitation but in the more severe forms even organic manifestations can occur. Proton pump inhibitors (PPIs) is the main medical ...

    • Immunological aspects on prognosis in resectable cholangiocellular cancer 

      Jansson, Hannes (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-06)
      Background: Biliary tract cholangiocellular cancers, cholangiocarcinoma (CCA) and gallbladder cancer (GBC), are malignancies with poor prognosis. Even after resection surgery with curative intent, a majority of patients ...

    • Targeting innate and adaptive immune responses to achieve long-term allograft acceptance following transplantation 

      Yao, Ming Han (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-03)
      Organ transplantation outcomes have gradually improved over the last 50 years. The development of more effective immunosuppressive drugs has been a major contributor to this improvement. However, current immunosuppressive ...

    • Perfusion computed tomography of the liver 

      Brehmer, Katharina (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-04-29)
      Background: Perfusion CT (P-CT) is a relatively new imaging technique that permits the visual and quantitative assessment of the micro- and macrocirculation of a target organ and focal lesions. P-CT has shown promising ...

    • Quantitative evaluation of liver function using gadoxetic acid-enhanced MRI 

      Wang, Qiang (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-04-29)
      Before liver resection, a reliable and accurate assessment of the liver function is essential to ensure a safe surgery and avoid unfavorable complications such as post-hepatectomy liver failure (PHLF). Gadoxetic acid ...

    • Psychotropic drug treatment during pregnancy and lactation : effects on mother and child 

      Whaites Heinonen, Essi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-04-28)
      The common major depressive disorder and anxiety disorders are often treated with antidepressants. Treatment with mood-stabilizers and antipsychotics are important for pregnant women with bipolar and psychotic disorders, ...

    • Retroperitoneal lymph node dissection for non-seminomatous germ cell tumour 

      Gerdtsson, Axel (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-29)
      Background: The Swedish and Norwegian Testicular Cancer Group (SWENOTECA) is a multidisciplinary collaboration with an aim to improve the testicular cancer care for patients in Sweden and Norway by publishing guidelines, ...

    • New technologies for the further advancement of ERCP 

      Reuterwall Hansson, Marcus (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-17)
      Background: The capabilities of conventional endoscopic retrograde cholangiopancreatography (ERCP) are hampered by several limitations. Newly developed adjunct technologies such as single operator peroral cholangiopancreatoscopy ...

    • Diagnosis and recovery patterns in patients with apraxia of speech after stroke 

      Hybbinette, Helena (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-02-10)
      Background: Stroke is a leading cause of adult disability. One of its most common consequences is a communication disorder. Beside aphasia (a language disorder), a motor speech disorder may occur, manifested as dysarthria ...

    • Delayed babbling at 10 months : observation, detection and a two-year follow-up 

      Lieberman Rubin, Marion (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-11-24)
      Babbling variables that can predict later expressive language, such as presence and onset of canonical babbling (CB), presence of anterior stops and consonant inventory, are suitable targets for a CB screening and the ...

    • Fewer kids not always by choice : the link between endocrine-disrupting chemicals and female reproductive health 

      Duque Björvang, Richelle (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-11-11)
      Fertility rates are declining from five children per woman in the 1950s to less than three children per woman in 2019. While this is partly due to women choosing to have fewer kids, there are growing evidence that ...

    • Biomarkers and outcome in children with hypoxic ischemic encephalopathy 

      Finder, Mikael (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-11-04)
      Approximately 1-6 per 1000 born infants will develop hypoxic-ischemic encephalopathy (HIE) with significant associated mortality and morbidity. For the past 45 years, severity of HIE has been stratified into mild, moderate, ...

    • Leukocyte scintigraphy, SPECT/CT and PET/CT in prosthetic joint infection 

      Teiler, Johan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-10-22)
      Background: A known complication of arthroplasty is prosthetic joint infection (PJI). It can be challenging to diagnose and treat PJI due to the formation of a biofilm protecting the bacteria in chronic infections from the ...

    • Orofacial function in children with speech sound disorders 

      Mogren, Åsa (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-10-21)
      Speech sound disorder (SSD) is one of the most common neurodevelopmental disorders in children and can have different aetiologies and outcome. Speech difficulties often co-exist with other disorders, such as motor difficulties ...

    • Adult patients with severe-to-profound hearing impairment : a clinical, register-based, and interview study 

      Turunen-Taheri, Satu (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-10-20)
      In Sweden, roughly 25,000 individuals in the adult population have severe-to-profound hearing impairment, a prevalence rate of 0.2-0.3%. This patient group often needs extended audiological rehabilitation. The general aim ...

    • Abdominal wall complications after urological surgery 

      Hermann, Maria (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-10-18)
      Background: Abdominal wall complications such as incisional hernia, bulging, and pain are known complications of surgery in the abdominal cavity. Most previous studies have been conducted on general surgical procedures, ...

    • Antisecretory factor in the perinatal period 

      Gustafsson, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-10-01)
      Preterm birth is the major cause of neonatal morbidity and mortality. Human milk, especially mothers’ own milk, has many health benefits for infants, especially infants born preterm. The causes of preterm birth are not yet ...