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  • Pathogenesis of IgA nephropathy and diabetic kidney disease : linking molecular profile to morphological and clinical picture 

    Levin, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-02-26)
    Background: More than 10% of the global population suffers from chronic kidney disease (CKD), which poses a large impact on society and, more importantly, the life of the affected patient. Two of the most common causes of ...
  • Targeting the ovary : mapping mechanisms to link endocrine-disrupting chemicals to female fertility 

    Li, Tianyi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-02-09)
    In recent decades, growing attention has been paid to endocrine-disrupting chemicals (EDCs) as mounting evidence suggests that they can cause detrimental reproductive outcomes in animals and humans. Even though epidemiological ...
  • Airway hyperresponsiveness and viral recognizing toll-like receptors 

    Starkhammar, Magnus (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-01-18)
    Common colds caused by viruses are, in healthy individuals, usually self-limited and with relatively mild symptoms. In asthmatic individuals, respiratory viruses can burst the defense immune system and trigger asthma ...
  • Treatment of cholelithiasis and acute cholecystitis : surgical safety in gallstone surgery 

    Blohm, My (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-11-06)
    INTRODUCTION: Laparoscopic cholecystectomy is one of the most frequently performed surgical procedures worldwide, with nearly 14,000 operations per year in Sweden alone. Recurrent biliary colic or acute cholecystitis are ...
  • Mesenchymal stem cell regeneration and differentiation after anti inflammatory drug exposure 

    Kumlin, Maritha (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-11-06)
    Traumatic and degenerative pathologies of the musculoskeletal system are common and often involve injuries of multiple mesenchymal tissues including bone, cartilage, tendons and ligaments. Medical intervention is frequently ...
  • Contrast-enhanced ultrasound in children 

    Torres Urzua, Alvaro (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-10-27)
    Background: Contrast-enhanced ultrasound (CEUS) is a diagnostic tool that is used for many applications in adults. Many of these applications are considered “off-label” use but still play an important role in diagnostic ...
  • Growing up with one ear : central auditory structure and function in unilateral ear canal atresia 

    Siegbahn, Malin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-10-17)
    The following thesis aims to give more insight into the functional and structural response of the central auditory system to congenital unilateral ear canal atresia (UCA) and the accompanying asymmetric hearing with ...
  • Multimodal treatment of gastric cancer : assessment of tumor regression and the role of minimally invasive surgery 

    Tsekrekos, Andrianos (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-08-23)
    The generally poor prognosis of advanced gastric cancer (AGC) has led to the development of multimodal therapeutic protocols in which surgery is combined with systemic treatment, perioperative chemotherapy being the ...
  • Immune cell composition and cytokine expression in the pregnant and non-pregnant uterus 

    Crona Guterstam, Ylva (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-05-23)
    The success of implantation and further development of the embryo is heavily dependent on the endometrial immune cell composition and its ability to communicate with fetal semi-allogeneic trophoblast cells. Although our ...
  • Microcirculation in chronic kidney disease : from injury targets to potential therapeutics 

    Arefin, Samsul (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-05-08)
    Chronic kidney disease (CKD) is a major public health problem worldwide, and patients with end-stage kidney disease (ESKD) are at increased risk of developing cardiovascular complications. Small artery dysfunction is a ...
  • Chronic kidney disease and early vascular ageing : pinpointing culprits of injury and targets for intervention 

    Hobson, Sam (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-04-19)
    Chronic kidney disease (CKD) is a progressive non-communicable disease, and a clinical model of premature ageing. Approximately 1 in 10 people globally have CKD, defined as abnormalities of kidney structure and/or function ...
  • Children with congenital unilateral sensorineural hearing loss : etiology, newborn diagnostics, and hearing aid amplification 

    Johansson, Marlin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-03-08)
    Congenital unilateral sensorineural hearing loss (uSNHL) comprises about 25% of the sensorineural hearing losses (SNHLs) found through newborn hearing screening (NHS) programs. Even if children with congenital uSNHL struggle ...
  • Mangement of acute cholecystitis : surgery, drainage and gallbladder aspiration 

    Popowicz, Agnieszka (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-01-27)
    Background: Early laparoscopic cholecystectomy is considered the standard of care for patients admitted with acute cholecystitis. Nevertheless, a large proportion of patients admitted for acute cholecystitis are managed ...
  • Idiopathic scoliosis : aspects on surgical and non-surgical treatment 

    Charalampidis, Anastasios (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2023-01-23)
    The term scoliosis has been used to describe conditions that lead to deformation of the spine. It derives from the ancient Greek ‘σκολίωσις’ and the root word ‘σκολιός’ which means ‘bent or crooked’. In its most common ...
  • Improvement of the diagnosis and management of cystic tumors of the pancreas 

    Ateeb, Zeeshan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-12-19)
    Pancreatic cancer is on its course on becoming the second cause of cancer related mortality. Although improvements have been made in the treatment arsenal, still only a minority of patients are able to receive treatment ...
  • Traction force and long-term outcome in children born after vacuum-assisted delivery 

    Romero, Stefhanie (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-11-18)
    Introduction: Vacuum-assisted delivery (VAD) is used in cases of dystocia or foetal distress in the second stage of labour. The frequency of VADs differs around the world, and in Sweden they account for six to nine percent ...
  • Pancreatic cancer : prevention through improved diagnostics in individuals at risk 

    Pozzi Mucelli, Raffaella (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-11-14)
    With the intent of timely detecting malignant precursors or pancreatic cancer (PC) in an early stage, current guidelines recommend surveillance for patients with pancreatic cystic neoplasms (PCNs), such as intraductal ...
  • Pelvic floor dysfunction after childbirth : symptoms, diagnosis, treatment 

    Rotstein, Emilia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-11-11)
    Vaginal delivery is a trauma to the levator ani muscles, the perineal muscles, and the anal sphincter complex (1-3). A levator ani deficiency cannot be surgically remedied and increases the risk of pelvic floor dysfunction ...
  • Chronic pain related to childbirth : prevalence, characteristics, women’s experiences about its impact and support from healthcare 

    Molin, Beata (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-11-08)
    Background: Pregnancy and labour often entail pain and tissue damage, which may lead to the development of chronic pain. Globally, chronic pain, defined as pain that persists after three months, is a leading cause of lasting ...
  • Inflammatory biomarkers in ANCA-associated vasculitis 

    Jónasdóttir, Ásta Dögg (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-11-02)
    Background: Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a heterogenous group of relatively rare and serious small vessel vasculitides, characterized by the presence of proteinase 3 (PR3) ANCA ...

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