Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 421-440 of 531
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Pharmacological and hormonal effects on bone with emphasis on osteoporosis : experimental studies in the rat
(Centrum för kirurgisk vetenskap CFSS / Center for Surgical Sciences CFSS, 2001-02-23)In this thesis influences of some hormones (17beta-estradiol and human parathyroid hormone) and drugs (risedronate and verapamil) on bone were investigated. The effects of verapamil, a phenylalkylamine calcium ... -
Invasion promoting factors in endometriotic and endometrial tissue
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2004-05-14)Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde ... -
Laparoscopic cholecystectomy : patients experiences of self-reported symptoms, perception of health and sense of coherence in a short and long term perspective
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2009-11-19)The aim of Study I was to explore patients' experiences related to gallstone disease and to their experiences of postoperative symptoms during the first week following outpatient laparoscopic cholecystectomy (LC). Twelve ... -
Human factors in image guided surgical simulator training : components, visual-spatial and haptic aspects
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2005-10-07)New image-guided surgical techniques such as arthroscopy and laparoscopy are difficult to learn and master. To handle these techniques, there seems to be a need for higher-level abilities such as visual-spatial abilities. ... -
Erythrocyte amino acids in health and renal failure and their association to the IGF-I/IGFBP-1 axis
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 1998-11-13)Abnormalities in amino acids (AA) metabolism in uraemia have mainly been reported to occur in plasma and muscle. No investigation has been undertaken to evaluate the AA levels in plasma, muscle and red blood cells (RBC) ... -
Preoperative staging and radiotherapy in rectal cancer surgery
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2006-09-29)Background: Rectal cancer affects approximately 2 000 people in Sweden every year. The overall survival rate is approximately 50% after five years. During the last decades the survival has increased and the local recurrence ... -
Pregnancy rhinitis : pathophysiological effects of oestrogen and treatment with oral decongestants
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-10-19)Pregnancy rhinitis, a common condition, is thought to affect about 20 % of pregnant women. This type of rhinitis may develop at any time during pregnancy and the nasal stuffiness usually disappears shortly after delivery. ... -
Preservation of fertility through cryopreservation and in vitro maturation of human ovarian follicles and oocytes
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2003-10-31)One of the most rapidly expanding fields in assisted reproduction is the preservation of fertility for young women at risk of premature ovarian failure. This may be caused by cytotoxic therapy or other reasons. Cryopreservation ... -
Helicobacter pylori infection among children in Riga, Latvia
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2006-12-29)Aims: To identify the prevalence of H.pylori among asymptomatic children and their parents in Riga, Latvia. To study the age of acquisition for H.pylori and the risk factors and symptoms associated with H.pylori infection. ... -
Diagnosing heart failure in primary health care
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2004-01-30)Diagnosing chronic heart failure (CHF) is difficult. General practitioners (GPs) have an important role in the management of heart failure patients, and the purpose of the studies was to examine their judgements of patients ... -
Methods for measurement of vocal fold vibration and viscoelasticity
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2009-05-08)The overall aim of the thesis was to develop new methods for analysis of vocal fold vibrations and viscoelasticity and to test them in human subjects. In Study I the onset of vibration and irregular vocal fold ... -
HPV genotyping and potential progression markers in cervical intraepithelial neoplasia : clinical and diagnostic impact
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2009-05-15)The aim of this thesis is to identify clinically useful early molecular markers to predict progression to carcinoma in women with preinvasive lesions of the cervix, for the purpose of improving care of these women and ... -
Strategies to improve macroencapsulated islet graft survival
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-10-05)Chronic immunosuppressive therapy may have severe side-effects. In cell transplantation, the graft can be encapsulated within a membrane chamber, providing a physical barrier against the immune system. The cell graft then ... -
On treatment and prognosis in epidermoid anal cancer
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2005-11-04)Epidermoid anal cancer is an uncommon, malignant disease that is diagnosed in approximately 100 patients annually in Sweden. The incidence is increasing worldwide. Over the past 30 years, a dramatic change in the therapeutic ... -
Polycystic ovary syndrome : a study of adipocyte lipolysis in relation to endocrine and metabolic status
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2003-05-14)The aim of the present thesis was to obtain insight into possible regulatory effects of androgens on the regulation of lipolysis in subcutaneous as well as visceral adipose tissue in women with the polycystic ovary syndrome ... -
Inborn errors in the metabolism of glutathione
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2002-11-15)Glutathione (GSH) is a tripeptide present in all mammalian cells. It takes part in several fundamental biological functions, including handling of reactive oxygen species (ROS), detoxification of xenobiotics and carcinogens, ... -
Multiple sclerosis : MRI diagnosis, potential treatment and future potential for nanoparticle applications
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2005-10-10)Multiple Sclerosis is an inflammatory demyelinating and neurodegenerative disease of the central nervous system. Magnetic resonance imaging is an important tool for diagnosing of Multiple Sclerosis and for, in vivo, ... -
Cytomegalovirus and herpes simplex virus infections in the fetus and newborn infant, with regard to neurodevelopmental disabilities
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2010-05-07)The congenital cytomegalovirus infection (CMV) is the most common congenital infection causing childhood morbidity. The majority (85%) of infected infants have no signs of infection in the newborn period, and when ... -
Prognostic molecular markers of childhood leukemia
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2010-05-21)During the last decades there has been a dramatic increase in survival rates for childhood leukemia, resulting today in an overall survival close to 90 % for children with acute lymphoblastic leukemia (ALL). This accomplishment ... -
Brain volume reduction over four decades in multiple sclerosis
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2010-05-07)Introduction: Multiple sclerosis (MS) is a common neurological disease causing intermittent or cumulative disability, predominantly among women of child-bearing age. MS is a chronic inflammatory disease of the central ...