Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 401-420 of 531
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Studies as a basis for a possible introduction of newborn screening for cystic fibrosis in Sweden
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-02-28)Background: Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. It is a multi-organ disease that results from mutations in the gene that encodes the CF transmembrane conductance ... -
Aspects of treatment of common bile duct stones
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-01-21)Background: Gallstone disease is a major cause of morbidity and at least 10 000 cholecystectomies are performed annually in Sweden. At the time of surgery about 5-15% of the patients also have common bile duct stones (CBDS). ... -
Costs and consequences in perioperative care : analytic models in studies on pain treatment and on haemodynamic optimization of elderly patients
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-01-20)Background: Because resources are scarce in health care, costs and consequences of new interventions must be assessed to support informed policy decisions. This thesis analyses the cost-effectiveness of advanced ... -
Computed tomography of the coronary arteries
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-01-14)Non-invasive coronary computed tomography angiography (CCTA) has become an important tool for visualisation of coronary arteries since the introduction of 64-channel detector CCTA in 2004. It has been proved to be especially ... -
Pattern-recognition receptors in airway inflammation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2010-12-15)Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. The ... -
Patients with head and neck cancer : aspects on treatment, complications and rehabilitation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2010-11-15)Head and neck cancer is reported to be the fifth most common cancer globally and around 1,200 new patients are diagnosed in Sweden every year. Historically, survival rates have been rather constant but have started to ... -
Digital imaging use : influence of digitalization on radiographers' work practice and knowledge demands
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2009-02-20)The aim: The purpose of this ethnographic study was to show how the radiographer s work practice and knowledge demands change in the transformation from analogue to distributed work. Method: The study adopts a ... -
Peripheral venous catheters : quality of care assessment
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2009-12-31)About half of the patients admitted to hospitals receive intravenous therapy through peripheral venous catheters (PVCs). Unfortunately, the use of PVCs is associated with the risk of complications that may lead to increased ... -
The wind of change : individuals change when technology change
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-11-26)The production of digital images has been well-known within radiology for many years through its use of modalities such as computer tomography, ultrasound and magnetic resonance tomography. During the latter part of the ... -
Synovial metabolism after different degrees of trauma : effects of pharmacological and physiological intervention : a microdialysis study of the knee joint synovium
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2010-04-21)Background: Knee arthroscopy is one of the most common orthopedic procedures. Postoperative pain and knee swelling is often a problem. Optimal pain management in knee arthroscopic procedures is important to permit same-day ... -
Local anesthesia for pain relief after surgery
(Centrum för kirurgisk vetenskap CFSS / Center for Surgical Sciences CFSS, 2001-11-16)Postoperative pain is a common problem in spite of increased awareness among patients and healthcare professionals. The prevailing practice is still to administer opiates, which have a good painrelieving potential but ... -
Psychological health and life situation in spouses of stroke patients
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-05-25)About 30,000 people in Sweden are affected by stroke each year. The effect on physical functioning, and also consequences such as depression and aphasia, are likely to affect not only the life of the patient, but also the ... -
Life situation, information needs, and information seeking in patients with oesophageal cancer and their family members
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2006-10-06)This thesis explores the experiences of living with oesophageal cancer from the perspective of patients and family members. Also, their needs for information and how they seek information in relation to the illness were ... -
Fat mass, adipokines and clinical complications of chronic kidney disease
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2006-05-26)Patients with chronic kidney disease (CKD), irrespective of initial etiology, have a risk of cardiovascular morbidity (CVD) and mortality that is many-fold higher than that of a similar person without CKD. While traditional ... -
Inflammation and matrix degrading proteases in coronary artery disease
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2006-05-26)Coronary artery disease (CAD) is a major cause of morbidity and death in the world today. The underlying process, atherosclerosis, is caused by lipid accumulation and inflammatory processes within the intimal layer of the ... -
Individual health, neighborhood characteristics, and allocation of primary health care resources
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2003-08-08)Aims: To examine whether neighborhood education and neighborhood income predict incidence rates of coronary heart disease (CHD), beyond individual characteristics (study 1); to examine whether neighborhood deprivation, ... -
Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2010-02-05)Background: The brain atrophy in individual Alzheimer's disease (AD) patients includes not only specific atrophy from AD pathology, but also atrophy induced by normal aging and cerebral vascular diseases. Although medial ... -
Cell transplantation and immunoisolation : studies on a macroencapsulation device
(Centrum för kirurgisk vetenskap CFSS / Center for Surgical Sciences CFSS, 1999-11-26)Encapsulation of cellular grafts in semipermeable membranes may provide a way to protect the graft from immune attack without the need for pharmacological immunosuppression. In this thesis, the use of immunoisolating devices ... -
Speech, voice, language and cognition in individuals with spinocerebellar ataxia (SCA)
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-05-25)Spinocerebellar ataxias (SCA) constitute a group of genetically defined hereditary, degenerative, progressive diseases affecting the cerebellum and its connections. Few previous investigations have focused on how SCA affects ... -
Role of ambulatory blood pressure monitoring after pediatric renal transplantation
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2008-11-14)Background: Office blood pressure (BP) readings, i.e., BP obtained in a clinical setting, are the basis of the present knowledge concerning the risks associated with hypertension. However, adult studies indicate ...