Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions

Now showing items 381-400 of 531

    • Reliability of visual assessment of medial temporal lobe atrophy 

      Cavallin, Lena (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2012-02-23)
      Background: Medial temporal lobe atrophy (MTA) has been found to be an early sign of Alzheimer’s disease (AD). Visual assessment of MTA (vaMTA) is a rapid, cost-efficient and clinically adaptable visual interpretation ...

    • Characterization of the BOLD signal in functional MRI 

      Jonsson, Tomas (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2012-01-19)
      In the last two decades, functional magnetic resonance imaging (fMRI) has become an important and widely used imaging technique for functional brain mapping. However, blood oxygen level dependent (BOLD) technique is quite ...

    • Restoration of scarred vocal folds with stem cell implantation : analyses in a xenograft model 

      Svensson, Bengt (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-12-22)
      Background: Tissue defects in the vocal fold (VF) caused by trauma, surgical procedures, post radiotherapy, often heal with scar formation. The scar tissue causes stiffness of the lamina propria rendering disturbed ...

    • Regeneration of the auditory nerve : a cell transplantation study 

      Palmgren, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-11-28)
      Since in mammals, the hair cells or the spiral ganglion neurons (SGNs) in the inner ear do not regenerate, damage to these cells is an irreversible process. Presently the only aid for patients with severe to profound hearing ...

    • Nutritional follow-up of patients with head and neck cancer 

      Tiblom Ehrsson, Ylva (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-11-22)
      Head and neck (H&N) cancer constitutes approximately 5.1% of all cancers worldwide and 2.2% in Sweden. It is a heterogeneous group of malignant tumours with differences in natural history and prognosis. The treatment is ...

    • Hip fracture in young and old subjects : aspects on risk factors and outcome 

      Al-Ani, Amer (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-11-18)
      Hip fractures, the most serious osteoporosis-related fractures, mainly affect older people. The functional outcome for many hip fracture patients remains to be improved. Hip fractures in young patients are uncommon, but ...

    • Severe childhood obesity : behavioural and pharmacological treatment 

      Danielsson, Pernilla (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-11-11)
      Background: Childhood obesity is a chronic disease associated with increased morbidity, psychosocial problems and reduced life expectancy, all of which is today very common. Despite this, long-term studies of behavioural ...

    • Multivariate data analysis applied to MRS and MRI studies of aging and spinal cord injury 

      Öberg, Johanna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-09-09)
      Magnetic resonance can be used for non-invasive studies of the body without the use of ionizing radiation. Magnetic resonance imaging and magnetic resonance spectroscopy have proven to be valuable utilities for research ...

    • Local pharmacological treatment of inner ear disorders 

      Engmér Berglin, Cecilia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-09-02)
      Hearing disorders are among the top 10 in terms of burden of disease in middle- and high-income countries, affecting 250 million people worldwide. During the last few decades researchers have made significant advances in ...

    • Renal function and renal histopathology in assessment of course and prognosis in Henoch Schönlein nephritis and IgA nephropathy 

      Edström Halling, Stella (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-08-31)
      Background: Henoch Schönlein Nephritis (HSN) is a common childhood vasculitis that generally has a self-limiting course but the long-term outcome varies with the clinical picture at onset. Morbidity is high among the ...

    • Nuclear medicine imaging of lung cancer and esophagus cancer 

      Herlin, Gunnar (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-08-24)
      Background: Somatostatin receptors (SSTRs) occur in cancer tissue, and 99mTc-depreotide is a labelled somatostatin receptor analogue, binding to SSTRs subtype 2, 3, and 5. Purpose: The general aim of the present ...

    • Neurological complications after stem cell transplantation in children 

      Rubin, Johanna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-05-26)
      Allogeneic haematopoietic stem cell transplantation (HSCT) is a well established method used in the treatment of a number of benign and malignant blood diseases, inborn errors of metabolism and severe congenital immunodeficiency ...

    • Human endometrial receptivity and embryo-endometrium interactions 

      Altmäe, Signe (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-05-25)
      Infertility is an increasing medical and social problem affecting more than 10% of couples worldwide. Many underlying causes of human infertility have been overcome by assisted reproductive techniques; nevertheless, the ...

    • Cochlear mechanics : design and application of superresolution techniques in the cochlear apex 

      Jacob, Stefan (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2011-05-19)
      Hearing is one of the five traditional senses. Next to vision it is probably the most important for man and plays a crucial role in day-to-day communication. However, hearing is extremely challenged by modern life style, ...

    • Adipose and muscle tissue metabolism in cancer cachexia 

      Agustsson, Thorhallur (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-05-10)
      Background: Loss of adipose and muscle tissue mass is a key feature of cancer cachexia. Weight loss, glucose intolerance, and insulin resistance are seen in patients with pancreatic ductal adenocarcinoma (PDAC). The mechanism ...

    • Renal failure in experimental sepsis : role of endothelin and the toll-like receptor 4 

      Fenhammar, Johan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-05-05)
      Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction ...

    • Moderately preterm infants : studies on length of hospital stay and neonatal outcome 

      Altman, Maria (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-05-03)
      Objective: Moderately preterm infants account for a large proportion of admissions and bed-days in neonatal units. Determinants of length of hospital stay, contemporary measures of morbidity by gestational week and risk ...

    • Intravenous access in distressed children : effects of midazolam and nitrous oxide on success rate, hormone and metabolic stress responses 

      Ekbom, Kerstin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-04-29)
      Background and Aims: Intravenous (IV) access has demonstrated high levels of pain and distress in children. A stress full IV access should be avoided, primarily by the children, but also for the parents and staff. When ...

    • Factors influencing splanchnic microcirculation in animal models of endotoxaemia 

      Andersson, Andreas (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-04-20)
      Even though severe sepsis and septic shock therapy has improved in recent years, mortality remains high (22-50%). Disturbances in splanchnic organ homeostasis and increases in gut permeability have long been presumed to ...

    • A walk into the digital world : a long and winding road 

      Fridell, Kent (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2011-03-01)
      Radiology departments are changing rapidly due to the implementation of digital image management and PACS (Picture Archiving and Communication Systems). When new information and communication technologies are implemented, ...