Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 321-340 of 531
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Studies of specific viruses from Guthrie cards and prognostic markers in bone marrow samples from children diagnosed with leukemia
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-05)Aims: The aim of this thesis was to increase understanding of how molecular processes influence the development and risk assessment of childhood leukemia. Studies I and II investigates whether a specific virus infection ... -
Alternatives in the treatment of abdominal rectus muscle diastasis : an evaluation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-10-23)Introduction: Abdominal rectus diastasis (ARD) is defined as a widening of the distance between the two rectus muscles located on either side of the Linea Alba (LA). A width of more than 3 cm is, in this thesis, considered ... -
Bimanual movement control : insights from golf ball striking
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-10-22)The aim of this thesis was to gain insight into the control of complex bimanual movements that are both fast and accurate. For this, skilled golf ball striking was used as a model in two experimental studies (I and III). ... -
Learning by doing : radiographers' knowledge and learning strategies in the digitized healthcare environment
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-10-21)The aim of this thesis was to inform the field of radiography of changes related to the digital image production process, by understanding how radiographers perform tasks and apply knowledge as well as learning strategies ... -
Speech and expressive language in Swedish-speaking children with unilateral cleft lip and palate
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-09-01)Introduction and aims: A cleft palate may hamper development of speech and expressive language. Expressive language, including phonology, has been sparsely explored in children with cleft lip and palate, and extended ... -
Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-25)BACKGROUND: Psychotic-like experiences (PLEs) and juvenile mania in adolescence index risk for severe psychopathology in adulthood. The importance of childhood problems with communication, reading, speech and mathematics ... -
Regulation of protein synthesis in human skeletal muscle : separate and combined effects of exercise and amino acids
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-05-22)Skeletal muscle is a highly plastic tissue which has the ability to adapt to various forms of external stimuli such as diverse modes of contractile activity. Thus, performance of endurance exercise over several of weeks ... -
Virtual patients for assessment of clinical reasoning
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-05-21)In healthcare education it is essential for the students to develop and achieve clinical reasoning skills. Clinical reasoning is complex to teach and learn, and effective assessment methods are also lacking. Virtual Patients ... -
Culture and vitrification of human preembryos
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-05-16)Despite improvements in stimulation protocols, culture media formulations and laboratory protocols, the success rates in human IVF remain disappointingly low. The ability to successfully cryopreserve supernumerary embryos ... -
Lexical and semantic development in children with cochlear implants
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-05-07)Introduction: Two important events have changed the prerequisites for children with severe-profound hearing impairment (HI). The first is the universal newborn hearing screening (UNHS) that enables early detection and ... -
Assessment and monitoring of nutritional status in chronic kidney disease patients
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-04-28)Patients with chronic kidney disease (CKD) often suffer from malnutrition and protein-energy wasting (PEW) resulting in poor nutritional status which is a powerful predictor of mortality. As it is not clear how well ... -
Life circumstances of children and adolescents after cochlear implantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-03-17)Introduction: In Sweden, about 300 children every year are born with hearing impairment (HI), and about 50 of them with severe HI. Today, these children are treated with either hearing aid (HA) or cochlear implant (CI). ... -
Family-related obesity risk factors and dietary behaviours in high-risk populations : associations with child weight development
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-03-12)Background: Obesity rates in Swedish children are currently not increasing, however socioeconomic disparities are widening. Many children become obese as early as their preschool years. Hereditary and environmental ... -
Renal Klotho in mineral metabolism
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-02-27)Calcium and phosphorous are critical elements in a number of physiological processes, including maintenance of bone structure, cell signaling and energy metabolism. Their endocrine regulation is tightly controlled through ... -
Theranostics in radiology : development of targeted contrast media with treatment capability
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-02-21)Imaging is essential in the diagnostics and medicine of today. The development of new contrast agents is important for obtaining specific information from images and to distinguish disease. Microbubbles (MB) have previously ... -
Vitamin D insufficiency in cystic fibrosis : prevalence, consequences and intervention
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-02-04)Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. The major cause of morbidity and mortality is lung disease, characterized by a vicious circle of infection and inflammation. ... -
Persistent geotropic nystagmus : a different kind of cupula pathology
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-02-04)In patients with positional vertigo a persistent positional direction-changing nystagmus (PDCN) of apogeotropic direction (a-PDCN) in the supine yaw plane has been described earlier 1-5. It has been suggested that the ... -
The expression of the structural proteins dendrin and Neph1 in the glomerular filtration barrier in proteinuria
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-01-22)Background: In the normal kidney, the glomerular filtration barrier successfully clears about one litre blood per minute. Damage to the filtration barrier might lead to protein leakage in the urine – proteinuria. The major ... -
Hypoxia-inducible factor-1 (HIF-1) in pancreatic cancer cell aggressiveness and therapeutic resistance and the potential role for pancreatic endocrine cells in islet transplantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-12-20)Tissue hypoxia results from an inadequate supply of oxygen (O2) that compromises biologic functions in various tissues, including both normal and malignant. It is known that a heterodimeric transcription factor hypoxia-inducible ... -
Pattern-recognition receptors and neutrophils in cancer inflammation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-12-19)Chronic inflammation, induced by the use of tobacco and alcohol, or caused by infections has long been suggested to constitute a risk factor for head and neck squamous cell carcinoma (HNSCC). The innate immunity is the ...