Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 301-320 of 531
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Sulfur amino acids and their metabolites in patients with renal failure : relation to nutritional status and cardiovascular disease
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2001-01-12)Patients with chronic renal failure (CRF) have a high prevalence of cardiovascular disease (CVD), malnutrition and diabetes mellitus (DM) and exhibit several abnormalities in amino acid metabolism. The aims of this thesis ... -
The cerebral circulation in preeclampsia : abnormalities in autoregulation and perfusion
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2001-02-02)Background: Eclampsia continues to be a major cause of maternal death. Abnormal cerebral blood flow and autoregulation may play an important role in the causation. Doppler ultrasound now allows assessment of the pathophysiology ... -
Mathematical modeling of fluid and solute transport in peritoneal dialysis
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2001-01-24)Optimization of peritoneal dialysis schedule and dialysis fluid composition needs, among others, methods for quantitative assessment of fluid and solute transport. Furthermore, an integrative quantitative description of ... -
Effects of alcohol consumption on health and mortality
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2001-01-26)During the last 25 years, alcohol consumption has become a widely debated issue, especially due to research results, in which the beneficial effects of alcohol on health and mortality have been maintained. Research has ... -
Breathing and phonation : effects of lung volume and breathing behaviour on voice function
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-12-29)Respiration is believed to play a central role in voice function and is thus of relevance to the clinical care of the disordered voice. The overall aim of the present study was to experimentally investigate relationships ... -
The effects of haemodialysis and metabolic acidosis on protein metabolism
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-11-24)Chronic renal failure and uraemia are characterised by gradual loss of renal function with an accumulation of metabolic and toxic waste products as well as disturbances in several organs and hormone functions. Two factors ... -
Nuclear medicine imaging of breast cancer and regional lymph nodes
(Centrum för kirurgisk vetenskap CFSS / Center for Surgical Sciences CFSS, 2000-11-17)The aim of this thesis was to explore the role of nuclear medicine in diagnosis of primary breast carcinoma and regional lymph node involvement. The introduction includes a review over nuclear medicine techniques currently ... -
Re-establishing reading skills of elderly low vision patients : studies on Swedish low vision clinic clients
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-11-17)This thesis is based on the project "Reading skills, reading training and technology for the visually handicapped - Prospects for the 1990s," carried out at the Department of Educational Research of the Stockholm Institute ... -
Individual glucocorticoid sensitivity in the human
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-11-17)The expanding use of inhaled and intranasal glucocorticoid (Gc) preparations for treatment of mild-to-moderate asthma and allergic rhinitis has in the last decade greatly increased the number of adults and children chronically ... -
Corneal cellular proliferation and wound healing
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-10-27)Background: Cellular proliferation plays an important role in both physiological and pathological processes. Epithelial hyperplasia in the epithelium, excessive scar formation in retrocorneal membrane formation and ... -
Malnutrition in patients with chronic renal failure
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-10-20)Protein-energy malnutrition is common in patients with chronic renal failure (CRF) and may contribute to a poor clinical outcome. However, the role of nutrition in this regard has not been clearly defined. Malnutrition in ... -
Water, hyaluronan and surface shape in corneal wound healing after excimer surgery : experimental studies
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-10-13)Excimer laser photorefractive keratectomy (PRK) has evolved to a widely performed procedure. The excimer laser corrects refractive ametropias by removing a calculated amount of anterior corneal stroma with great precision ... -
Clinical studies of contact granuloma and posterior laryngitis with special regard to esophagopharyngeal reflux
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2000-09-29)This investigation had two main goals. The first goal was to evaluate the clinical symptoms and signs of contact granuloma patients and to study the short-and long-term treatment outcomes. The second goal was to determine ... -
Strategies to improve outcome after islet transplantation using the GLP-1 receptor agonist, extendin-4
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-05-04)Transplantation of pancreatic islets into the liver via the portal vein has emerged as a treatment option for patients with type I diabetes mellitus. However, loss of functional beta cell mass during isolation and following ... -
Icodextrin metabolism in peritoneal dialysis : clinical and experimental studies
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2005-08-31)Icodextrin (ICO, or polyglucose) is an effective osmotic agent for peritoneal dialysis (PD) patients (pts). ICO is a soluble polymeric form of glucose with an average molecular 'weight range from 13,000 to 19,000 dalton. ... -
Effects of increased levels of androgens on voice and vocal folds in women with congenital adrenal hyperplasia and female-to-male transsexual persons
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-21)Voice virilization in women may occur due to increased levels of androgens. Women with congenital adrenal hyperplasia (CAH) are at risk for voice virilization due to an enzyme deficiency that causes increased production ... -
Genetic association studies in allergic rhinitis
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-20)Allergic rhinitis (AR) is a global health problem that causes major disability worldwide. Nasal obstruction, secretion and itching are characterizing features of the disease. The development and severity of AR are determined ... -
Lower urinary tract dysfunction in children with chronic kidney disease : before an after renal transplantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-14)Chronic kidney disease (CKD) in children is a complex condition with the risk of progression to end-stage renal disease (ESRD) requiring dialysis or renal transplantation. Children with CKD and pediatric renal transplant ... -
'Hay fever' in children : the real story
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-14)Rhinitis, allergic (AR) and non-allergic (NAR), and chronic rhinosinusitis (CRS) are different expressions of upper airway inflammation. Chronic upper airway symptoms are common in childhood and adolescence. There is a ... -
New approaches to treat women’s urogenital problems
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2014-11-10)Women’s urogenital problems adversely affect their quality of life. In this thesis, I address tw oof such urogenital problems: namely, postmenopausal vaginal atrophy (VA) and stress urinary incontinence (SUI). In the first ...