Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 341-360 of 531
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Congenital CMV infection and connexin 26 mutations in childhood deafness : intervention with early cochlear implantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-11-22)Hearing impairment (HI) is a common disability, which affects a significant proportion of the population. Early in life, however, the risk of acquiring a HI is low, with 0.2 % of all newborns having a permanent HI, and of ... -
Studies on bone and mineral disorders in CKD : determinants and survival implications
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-11-20)Disruptions in mineral metabolism occur already at an early stage of chronic kidney disease (CKD) and may eventually lead to a complex of CKD - mineral and bone disorders (CKD-MBD) characterized by alterations of the mass, ... -
Speech and voice characteristics in multiple sclerosis and cervical spinal cord injury : descriptive studies and effects of respiratory training
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-11-05)Introduction and aims: Respiratory function may be impaired in multiple sclerosis (MS) and cervical spinal cord injury (CSCI), but few studies have reported voice and speech data before and after respiratory training in ... -
Contrast enhanced ultrasound (CEUS) in breast tumors
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-11-05)Contrast-enhanced ultrasound or CEUS is a combination of the pharmacokinetics of contrast agents (or microbubbles-based ultrasound contrast agents), the signal processing of these agents and the contrast-specific imaging ... -
Maternal microchimerism
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-10-31)Microchimerism refers to one individual harboring cells or DNA at a low level that derive from another individual. The most common source is pregnancy when cells from the fetus and the mother pass the placenta bidirectionally, ... -
Upper airway surgery in obstructive sleep apnoea : descriptive, observational and randomised controlled studies
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-10-30)Obstructive sleep apnoea syndrome (OSAS) is a general health problem which causes daytime sleepiness, impaired quality of life and increased morbidity and mortality. A narrow upper airway anatomy is a common cause of OSAS, ... -
Radiographic quality workflow : in the digitized healthcare environment
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-10-04)This thesis emphasizes two different aspects — how radiographers use knowledge in image production work and perceive a radiographic quality workflow in the digitized healthcare environment using PACS — both because these ... -
On fixation of hip resurfacing implants
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-09-03)Hip resurfacing became a recognized entity in hip replacement in the 1970’s. This generation of resurfacing implants was abandoned due to loosening and debris. The interest in resurfacing was renewed due to the need of a ... -
Development of classical Hodgkin’s lymphoma in an adult with biallelic STXBP2 mutations
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2013-07-31)Experimental model systems have delineated an important role for cytotoxic lymphocytes in the immunosurveillance of cancer. In humans, perforin-deficiency has been associated with occurrence of hematologic malignancies. ... -
The role of FGF23/Klotho in mineral metabolism and chronic kidney disease
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-07-25)Chronic kidney disease (CKD) is a global health burden of growing incidence and prevalence. As renal function declines disturbances in mineral metabolism, such as hyperphosphatemia and secondary hyperparathyroidism, ... -
Iatrogenic bile duct injury during cholecystectomy
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-06-17)Background: Accidental injuries to the bile ducts are a rare but devastating complication to cholecystectomy, causing afflicted patients considerable morbidity, with subsequent impaired quality of life and significant ... -
Go with the flow : to facilitate learning in laparoscopic gynecology
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-22)Background: Education in medicine, particularly in surgical disciplines, is crucial since it affects patient safety. The learning process is dependent on individual abilities, prior knowledge and the learning environment. ... -
Clinical grade vitrification of human ovarian tissue for fertility preservation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-16)Cryopreservation of human ovarian tissue is one approach to preserve fertility for women who can be predicted to undergo premature ovarian failure as a consequence of chemotherapy, radiotherapy or genetic disorders. It is ... -
Pancreatic fistula following pancreaticoduodenectomy : risk assessment and early diagnosis
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-08)Pancreaticoduodenectomy (PD), a complex surgical procedure for resecting tumors of the pancreatic head, distal bile duct or periampullary region, is associated with a considerable morbidity. Postoperative pancreatic fistula ... -
Determinants and clinical implications of circulating fatty acids in individuals with chronic kidney disease
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-07)Patients with chronic kidney disease (CKD) have a high risk of cardiovascular morbidity and mortality. Adding to traditional risk factors, e.g., Framingham risk factors, novel risk factors including inflammation, insulin ... -
Teamwork training using patient simulation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-06)Teamwork is an important factor in safe healthcare. Simulation based team training (SBTT) is a method to gain the non-technical skills important for proficient teamwork. This thesis evaluated SBTT using different modalities ... -
Avatar : saving lives in virtual worlds
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-05-03)In medicine, education and recurrent training is fundamental for efficient and safe care. In emergency situations one has to rely on robust protocols that reduce the risk for errors. However, today there is plenty of ... -
Cellular replacement therapy for liver disease
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-04-04)Liver disease is a major health problem worldwide. The liver performs a wide range of functions, which the human body cannot survive without. The human liver is continuously challenged with infectious organisms, alcohol ... -
Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2013-03-25)The major histocompatibility complex class II transactivator (CIITA) gene (16p13) has been reported to associate with susceptibility to multiple sclerosis, rheumatoid arthritis and myocardial infarction, recently also to ... -
Novel potential targets for treatment of airway inflammation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2013-03-04)Allergy is a complex biological response mediated by several different cell types including B lymphocytes, T lymphocytes and eosinophils. From clinical observations it is well-known that microbial infections, in particular ...