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  • Occupational safety and health interventions : incentives and economic consequences 

    Martinsson, Camilla (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-08-28)
    Aim: The overall aim of this thesis was to extend the knowledge of factors that from an employer perspective could increase the use of research based occupational safety and health (OSH) interventions and work-place health ...
  • p73 - regulator of differentiation and apoptotic cell death 

    Nyman, Ulrika (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2007-05-04)
    Neoplasia is characterized by cells' loss of self-control due to deregulated apoptotic and cell proliferation pathways. Anticancer treatments aim to induce either cell cycle arrest or apoptosis, and these effects are ...
  • Apoptotic cell death in neural stem cells exposed to toxic stimuli 

    Tamm, Christoffer (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2006-01-25)
    Neural stem cells (NSCs) play an important role in the developing nervous system and adulthood, where mitotic regions of the brain such as the subventricular zone (SVZ) remain active. In spite of the immense interest in ...
  • Diet and ovarian cancer : A population-based cohort of 60 000 women 

    Larsson, Susanna C (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2005-05-06)
    Ovarian cancer represents the fourth leading cause of cancer-related mortality among women in Western countries. Hence, identification of risk factors amenable to modification, such as diet, is of considerable public health ...
  • Flying personnel : cancer, acute myocardial infarction and mortality 

    Linnersjö, Anette (Institutet för miljömedicin / Institute of Environmental Medicine, 2014-05-19)
    Aim: Flying personnel are exposed to several factors in the work environment that can potentially increase their cancer incidence, mortality and acute myocardial infarction (AMI) incidence. The aim of this licentiate thesis ...
  • Cumulative assessment of persistent organic pollutant toxicity in vivo 

    Westerholm, Emma (Institutet för miljömedicin / Institute of Environmental Medicine, 2011-05-02)
    Humans are continuously exposed to a multitude of compounds present in the environment and in food. A major challenge in risk assessment is to determine the degree of exposure to multiple chemicals and the hazards associated ...
  • Mdm2 phosphorylations : Characterization and applications 

    Malmlöf, Maria (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2007-09-07)
    Cancer is a widespread disease. In spite of all research resulting in new improved therapies, there are still many tumors that cannot be cured. To oppose that, also a preventive research approach is important with ...
  • Exposure to inorganic arsenic in pregnancy and metabolism-nutrition interaction 

    Li, Li (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2006-11-10)
    Inorganic arsenic is metabolized by most mammals, including humans, via alternating reduction and oxidative methylation with S-adenosylmethionine as main methyl donor. Thus, it seems likely that it is influenced by ...
  • Novel methods for the identification of cellular S-glutathionylated proteins and sites of glutathionedependent modification using affinity chromatography and proteomic analyses 

    Hamnell-Pamment, Ylva (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2005-02-21)
    Reactive oxygen species (ROS) are formed during normal respiration in the mitochondria through electron leakage to oxygen. During normal metabolism, several enzymes and low-molecular weight antioxidants work towards ...
  • The mouse oocyte as a model in reproductive toxicology studies 

    Zhang, Jinwen (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2007-10-18)
    It is suspected that certain chemicals may cause alterations in female reproduction, including ovarian failure and birth defects. Sub-fecundity, infertility, pregnancy loss, fetal growth retardation, and birth defects are ...

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