Licentiatavhandlingar / Licentiate Theses - C4 (Neuro)
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Recent submissions
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Is modulation of glucocerebrosidase a viable new treatment for Parkinson's disease?
(Inst för neurovetenskap / Dept of Neuroscience, 2019-09-30)Background: Parkinson's disease is the second most prevalent neurodegenerative disorder. There are currently no treatments that cure Parkinson’s disease (PD) or slow its progression. There is therefore an urgent need for ... -
Home-cage monitoring of mouse behaviours across life-span
(Inst för neurovetenskap / Dept of Neuroscience, 2019-04-25)Background and aim: The academic research involving animal testing is struggling with problems of reproducibility and a few of the specific reasons pointed out are for example insufficient reporting of animal strains and ... -
Modulation of acetylcholine release by serotonergic 5-HT1A and 5-HT1B receptors : a microdialysis study in the awake rat
(Institutionen för neurovetenskap / Department of Neuroscience, 2007-05-25)The aim of the thesis was to investigate the effects of the 5-HT1A receptor antagonist robalzotan (NAD-299) and the 5-HT1B receptor antagonist NAS-181 ((R)-(+)-2-(3-morpholinomethyl-2Hchromen-8-yl) oxymethyl-morpholine ... -
Multimethodological imaging studies of pathophysiological mechanisms in human epilepsy
(Institutionen för neurovetenskap / Department of Neuroscience, 2006-08-11)Although the pathophysiological mechanisms of human epilepsy are extensively investigated, many questions remain unanswered. One is whether idiopathic generalized epilepsies (IGE) have anatomical substrates. Another is if ... -
The effect of caloric restriction on age-related hearing loss and the impact of repeated sound exposures
(Inst för neurovetenskap / Dept of Neuroscience, 2013-10-18)The auditory system is the sensory system responsible for hearing and crucial for communication between individuals. While aging, many organs of the body start losing their function, including the hearing organ. The severity ... -
Assessment of environmental contaminants' neurotoxicity : in vitro and in vivo experimental studies
(Inst för neurovetenskap / Dept of Neuroscience, 2011-09-06)Accumulating evidence over several decades shows that environmental contaminants may lead to neurodevelopmental alterations. An essential prerequisite to prevention is recognition of a chemical‟s ability to harm the ... -
Anatomical studies of hypothalamic thyrotropin-releasing hormone : implications for motivated states
(Institutionen för neurovetenskap / Department of Neuroscience, 2010-05-14)The survival of every animal as an organism and species depends on three motivated states: ingestive, defensive and reproductive. Regulation of these states is coordinated by the hypothalamus through the coordination of ... -
Analysis of different forms of locomotor behavior in lamprey
(Institutionen för neurovetenskap / Department of Neuroscience, 2007-05-25)The ability to locomote, that is move actively in space, is characteristic of the animal kingdom. Many species are capable of different forms of locomotion. They include forward and backward locomotion, fast and slow ...