Artiklar / Articles - SwePub: Recent submissions
Now showing items 81-100 of 404
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Association between levels of sex hormones and risk of esophageal adenocarcinoma and Barrett’s esophagus
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2020-03-18)Background & Aims: Esophageal adenocarcinoma (EAC) occurs most frequently in men. We performed a Mendelian randomization analysis to investigate whether genetic factors that regulate levels of sex hormones associated with ... -
Association between metformin use and risk of esophageal squamous cell carcinoma in a population-based cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2020-03-11)Objectives: Esophageal cancer is a highly fatal malignant neoplasm, with two etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% subtype of esophageal ... -
Effects of inhaled corticosteroids on DNA methylation in peripheral blood cells in children with asthma
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-09-25) -
Cardiac remodeling in aortic and mitral valve disease : a simulation study with clinical validation
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2019-09-03)Background: Remodeling is an important long-term determinant of cardiac function throughout the progression of heart disease. Numerous biomolecular pathways for mechanosensing and transduction are involved. However, we ... -
Sibship and dispensing patterns of asthma medication in young children : a population based study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-06)Purpose: Our aim was to study the association between sibship and dispensing patterns of asthma medication in young children, focusing on incidence and persistence, and taking sibship status, asthma diagnoses, and siblings’ ... -
Cesarean delivery, preterm birth and risk of food allergy : nationwide Swedish cohort study of over 1 million children
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-06)Background & Objectives: Little is known about early life risk factors for food allergy in children. We examined the association between perinatal characteristics and future risk of food allergy in offspring. Methods: ... -
Everyday technologies and public space participation among people with and without dementia
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-06-12)BACKGROUND: Occupational therapists support everyday technology use; however, it is necessary to consider the challenges that people with dementia encounter with everyday technologies when participating in various places ... -
Effects of design choices on the stiffness of wireframe DNA origami structures
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2019-04-24) -
Has the attention deficit hyperactivity disorder phenotype become more common in children between 2004 and 2014? Trends over 10 years from a Swedish general population sample
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-03-27)Background: Studies have reported increases in clinically diagnosed and treated Attention deficit hyperactivity disorder (ADHD) during the last decade, but it is unclear if this reflects an increase in the underlying ADHD ... -
Efficacy and cost-effectiveness of therapist-guided internet cognitive behavioural therapy for paediatric anxiety disorders : a single-centre, single-blind, randomised controlled trial
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-03-27)Background: Paediatric anxiety disorders are prevalent and associated with substantial disability and long-term adverse consequences. Only a minority of affected children have access to evidence-based treatment; ... -
How chronic is polypharmacy in old age? A longitudinal nationwide cohort study
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-03-14)OBJECTIVE: To evaluate the chronicity of polypharmacy among older adults, and to identify factors associated with chronic polypharmacy. DESIGN: Longitudinal cohort study using register data. SETTING: Nationwide, ... -
Ageing, deep vein thrombosis and male gender predict poor outcome after acute Achilles tendon rupture
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-03-14)Background: Patients with acute Achilles tendon rupture (ATR) exhibit prolonged healing, high incidence of deep venous thrombosis (DVT) and a wide variation of functional outcome. This extensive discrepancy in outcome may ... -
Reduced time to surgery improves patient-reported outcome after achilles tendon rupture
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-03-14)Background: Patient outcome after an acute Achilles tendon rupture (ATR) continues to be suboptimal and heterogeneous. Thus, prognostic factors are called for to optimize evidence-based ATR treatment protocols, however, ... -
Anticholinergic burden and risk of stroke and death in people with different types of dementia
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-02-20)Background. Anticholinergic burden is associated with poorer cognitive and functional outcomes in people with dementia. However, the impact of anticholinergics on significant adverse outcomes such as stroke has not been ... -
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis
(Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2019-02-11)Adhesion to the extracellular matrix persists during mitosis in most cell types. However, while classical adhesion complexes, such as focal adhesions, do and must disassemble to enable mitotic rounding, the mechanisms of ... -
Agreement between asthma questionnaire and health care register data
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)Purpose: Risk factors and consequences of asthma can be studied using validated questionnaires. The overall objective of this study was to assess the agreement of parental-reported asthma related questions regarding their ... -
Allergen-specific IgE over time in women before, during and after pregnancy
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)The trajectory of IgE levels before, during and after pregnancy in sensitized individuals is characterized by significant increase in specific IgE to birch allergens but not to other allergens after multiple testing. This ... -
Bidirectional relationship between eating disorders and autoimmune diseases
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)Background: Immune system dysfunction may be associated with eating disorders, and associations could have implications for detection, risk assessment, and treatment of both autoimmune diseases and eating disorders. However, ... -
Company employees as experimental participants in traffic safety research : prevalence and implications
(Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and EthicsInst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2018-11-08)The use of company employees as experimental participants when testing products, technology or paradigms developed by the same company raises questions about bias in results and research ethics. We aimed to investigate the ... -
Prognosis following cancer surgery during holiday periods
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2018-10-19)Surgery is the mainstay curative treatment in most cancer. We aimed to test the new hypothesis that cancer surgery performed during holiday periods is associated with worse long-term prognosis than for non-holiday periods. ...