Licentiatavhandlingar / Licentiate Theses: Recent submissions
Now showing items 81-100 of 252
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On aspects of context in rehabilitation after stroke : views of patients and therapeutists
(Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2006-09-15)Contextual factors have lately come more into focus contributing to the individual's health condition. Previous research indicates that contextual factors are poorly accounted for in stroke rehabilitation and that the ... -
Professional identity and competence in practice : self-evaluation of nurses in paediatric care
(Institutionen för kvinnors och barns hälsa / Department of Women's and Children's Health, 2006-09-29)Paediatric health care is becoming increasingly high-specialised and there is a need to employ, nurses with specialist knowledge in the field. A large turnover of personnel and shortage of specially training in paediatric ... -
Total physical activity in middle-aged and elderly women from a population-based cohort
(Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2006-11-22)Regularly performed physical activity (PA) is associated with a reduced risk of coronary heart disease, stroke, type 2 diabetes, some forms of cancer, osteoporosis, and all-cause mortality. Due to its role in health promotion ... -
Anterior cruciate ligament reconstruction with bone-patellar tendon-bone graft : postoperative intervention and influential factors for patient-relevant long-term outcome
(Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2007-04-13)The overall aim of the present thesis was to assess patient-relevant outcome after anterior cruciate ligament (ACL) reconstruction and to improve the knowledge of which factors that may predict longterm outcome after ... -
The road to diagnosis and treatment of patients with lung cancer
(Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2006-11-27)Lung cancer is the third most common cancer among men and women in Sweden. More than 3000 persons/year are diagnosed with lung cancer. Despite the presence of many and intense symptoms at diagnosis, most patients still ... -
Mapping the genome and characterization of an acetyltransferase of Trypanosoma cruzi
(Institutionen för cell- och molekylärbiologi (CMB) / Department of Cell and Molecular Biology, 2006-05-02)Trypanosoma cruzi (T.cruzi) is a flagellate protozoan parasite that causes Chagas' disease and is most common in Latin American countries. The disease currently infects over 13 million persons and about 100 million more ... -
Multimethodological imaging studies of pathophysiological mechanisms in human epilepsy
(Institutionen för neurovetenskap / Department of Neuroscience, 2006-08-11)Although the pathophysiological mechanisms of human epilepsy are extensively investigated, many questions remain unanswered. One is whether idiopathic generalized epilepsies (IGE) have anatomical substrates. Another is if ... -
Effects of high glucose on platelet activation
(Institutionen för medicin / Department of Medicine, 2006-08-07)Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This ... -
Molecular and cellular strategies to enhance efficacy of T cell-based cancer therapy
(Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2006-09-06)A combined approach of vaccination with β2-microglobulin (β2m)-deficient dendritic cells (DCs) and granulocyte-macrophage colony-stimulating factor (GM-CSF) as a potent adjuvant may link cellular and molecular strategies ... -
Expression of the glucose-6-phosphatase system in endocrine cells
(Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2006-05-26)Glucose-6-phosphatase (G6pase) is a multi-component enzyme system, which regulates the catalysis of gluco se-6 -phosphate (G6P) to glucose and inorganic phosphate. This reaction constitutes the final steps of both ... -
The effect of the tumor environment on the anti-tumor immune response
(Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2006-08-28)Cancer immunotherapy is the process of stimulating the host's immune system to kill cancer cells, and it is being investigated as adjuvant therapy to traditional cancer treatments such as, surgery, radiation therapy and ... -
The role of interferons in the resistance to infection with Chlamydia pneumoniae
(Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2006-05-25)Chlamydia pneumoniae is an obligate intracellular bacterial pathogen that infects the respiratory tract in human. IFN-gamma is an essential cytokine for the immune response triggered to limit infection with C. pneumoniae. ... -
Role of estrogen receptor beta in mouse ventral prostate with relation to human prostatic diseases
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2006-04-17)In this thesis we investigate role of estrogen receptor beta (ERbeta) in development and functioning of mouse ventral prostate, using it as a model for human extrapolations. ERbeta was discovered in 1995 and is a member ... -
Viral and host determinants in hepatitis B
(Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2006-05-26)The outcome of hepatitis B infection is highly variable, ranging from acute disease resulting in the elimination of infection to persistent infection that can lead to cirrhosis or hepatocellular carcinoma. The factors ... -
Coxsackie B virus pathogenesis in mice
(Mikrobiologiskt och Tumörbiologiskt Centrum (MTC) / Microbiology and Tumor Biology Center (MTC), 2006-05-18)Coxsackie B virus (CVB) belongs to the enterovirus (EV) genera of the Picornaviridae family. These infections range from asymptomatic, mild infections to serious diseases such as myocarditis, pancreatitis, paralysis, aseptic ... -
Characterisation of psoriasis lesions by protein expression profiling
(Institutionen för medicin / Department of Medicine, 2006-05-26)Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic ... -
Apoptotic cell death in neural stem cells exposed to toxic stimuli
(Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2006-01-25)Neural stem cells (NSCs) play an important role in the developing nervous system and adulthood, where mitotic regions of the brain such as the subventricular zone (SVZ) remain active. In spite of the immense interest in ... -
Induction of type I interferons and viral immunity
(Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2006-01-06)Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the ... -
Molecular epidemiology of hepatitis A, B and C in Estonia
(Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2006-03-31)During the last decade changes have occurred in the epidemiology of hepatitis A, B and C in Estonia. A shift from high to intermediate endemicity for HAV has led to a shift in age of susceptible individuals from children ... -
HHV-8/KSHV association with tumor cells during development of Kaposi sarcoma
(Institutionen för onkologi-patologi / Department of Oncology-Pathology, 2006-01-12)Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion which usually presents as a cutaneous disease and progresses to extracutaneous, systemic spread usually in the gastrointestinal (GI) tract, ...