Licentiatavhandlingar / Licentiate Theses: Recent submissions
Now showing items 61-80 of 254
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Efficacy of artemisinin based combination therapy and effectiveness of rapid diagnostic test for management of patients with plasmodium falciparum malaria in Zanzibar
(Institutionen för medicin / Department of Medicine, 2009-05-19)Background: Due to rapid spread of antimalarial drug resistance to Plasmodium falciparum malaria many African countries have recently changed their first-line treatment policy to artemisinin-based combination therapy (ACT). ... -
Smärta, infektion och återanpassning till livet efter en brännskada
(Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2010-01-22)A burn injury is an unforeseen event that includes a physical as well as a psychological trauma for the person afflicted. The trauma is experienced differently by individuals as do perceived problems during care, ... -
Limitations of maximal oxygen uptake during whole-body exercise
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2007-10-26)Oxygen uptake increases linearly with increased running speed or rate of work and finally reaches a maximum beyond which no effort can drive it further. This phenomenon is referred to as the plateau in oxygen uptake . ... -
Laparoscopic cholecystectomy : patient's experiences and self-reported symptoms the first week after surgery
(Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2007-11-29)Very little research has been conducted to identify patients own perspectives of having gallstone disease and their own experiences of symptoms the first postoperative week following laparoscopic cholecystectomy, LC. ... -
Modulation of acetylcholine release by serotonergic 5-HT1A and 5-HT1B receptors : a microdialysis study in the awake rat
(Institutionen för neurovetenskap / Department of Neuroscience, 2007-05-25)The aim of the thesis was to investigate the effects of the 5-HT1A receptor antagonist robalzotan (NAD-299) and the 5-HT1B receptor antagonist NAS-181 ((R)-(+)-2-(3-morpholinomethyl-2Hchromen-8-yl) oxymethyl-morpholine ... -
Post-operative delirium after elective cardiac surgery : risk factors and cognitive long-term outcome : results from a clinical study
(Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2009-05-07)Delirium is a serious problem in the older patient. Delirium is associated with a significant independent morbidity and mortality that increases hospital costs. Due to the increasing elderly population, delirium is ... -
Studies of innate immune stimulation with CpG in HIV infection
(Institutionen för mikrobiologi, tumör- och cellbiologi / Department of Microbiology, Tumor and Cell Biology, 2008-10-01)Two types of human immunodeficiency virus (HIV) may cause acquired immune deficiency syndrome (AIDS): HIV-1, the most pathogenic virus of the two and found worldwide, and HIV-2, which is mostly detected in West Africa and ... -
Genetic analysis of type 1 diabetes susceptibilty
(Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2008-11-21)Type 1 diabetes (T1D) is a multifactorial disease where the pancreatic beta-cells are destroyed in an autoimmune attack. For the patients, this in turn leads to lifelong daily insulin treatment and increased risk for various ... -
The meaning of health and sexuality as experienced by Tanzanian men and women living with HIV/AIDS
(Institutionen för folkhälsovetenskap / Department of Public Health Sciences, 2007-05-22)Background: Sub-Saharan Africa has for more than two decades been hit by the human immunodeficiency virus/acquired immune-deficiency syndrome, HIV/AIDS pandemic. In Tanzania, the prevalence of HIV is estimated to 7 percent ... -
Strategies to improve outcome after islet transplantation using the GLP-1 receptor agonist, extendin-4
(Institutionen för klinisk vetenskap / Department of Clinical Sciences, 2007-05-04)Transplantation of pancreatic islets into the liver via the portal vein has emerged as a treatment option for patients with type I diabetes mellitus. However, loss of functional beta cell mass during isolation and following ... -
Weight loss programmes over the internet : opportunities and limitations
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2007-11-21)Background: Overweight and obesity is increasing in Sweden and over the world. The societal resources to treat obesity are scarce. Eighty percent of the population in Sweden have access to a computer and hence the Internet. ... -
Observational and experimental studies of drug treatment of infection and myocardial infarction/depression in a hospital in St. Petersburg
(Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2008-01-11)Introduction: Treatment of infectious and cardiac diseases represents subjects of great concern for health care all over the world, e.g. in Russia. Major problems may occur in routine use of the drugs that need to be timely ... -
Characterization of brn1.2 and corticotropin-releasing hormone genes in zebrafish
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2007-11-16)The zebrafish (Danio rerio), a tropical fresh water fish originally found in the rivers of India and Bangladesh has become a popular vertebrate model system over the last decade. The rapid sequencing of the zebrafish genome ... -
Studies on the molecular regulation of bile acids and lipoproteins in human liver
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2007-11-23)Elevated lipid levels in the bloodstream, in particular high levels of LDL cholesterol, are a major risk factor for the development of atherosclerosis. The liver has a central role in cholesterol metabolism and is the only ... -
Prevalence of malnutrition and determinants of nutritional status among elderly people : a population-based study in rural Bangladesh
(Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2007-01-10)Introduction: Both the number and proportion of persons aged 60+ years are growing rapidly in almost all countries of the world. Research shows that elderly people are nutritionally vulnerable and that their nutritional ... -
p73 : regulator of differentiation and apoptotic cell death
(Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2007-05-04)Neoplasia is characterized by cells' loss of self-control due to deregulated apoptotic and cell proliferation pathways. Anticancer treatments aim to induce either cell cycle arrest or apoptosis, and these effects are ... -
Ascorbate in the ocular lens
(Institutionen för klinisk neurovetenskap / Department of Clinical Neuroscience, 2006-09-27)Purpose: First, we intended to establish a method for sample preparation for measurement of ascorbate in whole rat and guinea pig lenses utilizing ultrafiltration and high performance liquid chromatography with ultraviolet ... -
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(Institutionen för medicin / Department of Medicine, 2006-09-15)Myasthenia gravis (MG) is an autoimmune disease characterized by the production of antibodies against the skeletal muscle acetylcholine receptor (AChR). MG is usually associated with thymic disorders including thymoma ... -
Methods and detection of endogenous peptides in the CNS and GI tract
(Institutionen för medicin / Department of Medicine, 2006-11-15)Endogenous peptides, such as enkephalins, endorphins and orexins modulate a variety of biological processes; these peptides are found in the central nervous system and periphery, including the gastrointestinal tract. One ... -
Expression and post-translational modification of purple acid phosphatase in insect and mammalian cells
(Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2006-11-29)Purple acid phosphatase (PAP) is an acidic metallohydrolase that contain a binuclear iron center in its active site. In mammals, this enzyme is also referred to as tartrate-resistant acid phosphatase (TRAPs), uteroferrin ...