Now showing items 1-20 of 242

    • Common respiratory virus infections in cystic fibrosis : from immunity to vaccine 

      Utorova, Renata (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2020-05-27)
      Cystic fibrosis is the most common lethal monogenetic disease in Caucasians. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator protein which is responsible for appropriate ion and water ...
    • Hygiene at CT and MRI 

      Palmqvist, Charlotte (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-05-26)
      Background: Preventing the spread of infections is a constant battle against microorganisms. Hospital-acquired infections (HAIs) with multidrug-resistant (MDR) bacteria are a global problem today and causes suffering for ...
    • Between the lines : gambling among athletes and coaches in four elite sports 

      Vinberg, Maria (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-04-23)
      Background and aim: Knowledge of how gambling and problem gambling are distributed in different societal groups is valuable for developing preventive initiatives. Considering the financial connections between sports and ...
    • Sickness absence and disability pension among individuals injured in a bicycle crash 

      Kjeldgård, Linnea (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-04-21)
      Bicyclists are the road user group with the highest number of severe injuries, yet little is known about the impact of such injuries on sickness absence (SA) and disability pension (DP). Therefore, the aim was to increase ...
    • Paving the way : the second generation of e-patients, their experiences, actions and driving forces 

      Scott Duncan, Therese (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2020-04-16)
      Background: E-patients are described as patients and informal caregivers who are empowered, equipped, enabled and engaged, and use digital solutions for their self-care and in healthcare contexts. Self-care can be understood ...
    • Hearing in Children with cleft palate 

      Tengroth, Birgitta (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-02-21)
      Objective: The overall aim of this thesis was to collect longitudinal information about hearing thresholds and complications due to otitis media with effusion (OME) in children with cleft palate. Since OME is highly prevalent ...
    • Hormonal and metabolic effects of diet and physical exercise in overweight/obese women with polycystic ovary syndrome. 

      Nybacka, Åsa (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-11-22)
      Background: Overweight/obese women with polycystic ovary syndrome (PCOS) often have hormonal problems characterized by irregular menses and decreased fertility. In addition, the overweight/obese women carry metabolic ...
    • PET/CT with 18F-FDG and 68Ga-DOTATOC in pulmonary carcinoid imaging 

      Uhlén, Natalja (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-10-11)
      Background: PET/CT, positron emission tomography combined with computed tomography, with 18F-FDG (2-deoxy-2-[18F]fluoro-D-glucose) is well established in oncological imaging. Pulmonary carcinoid tumours may have metabolic ...
    • Is modulation of glucocerebrosidase a viable new treatment for Parkinson's disease? 

      Zurbruegg, Mark (Inst för neurovetenskap / Dept of Neuroscience, 2019-09-30)
      Background: Parkinson`s disease is the second most prevalent neurodegenerative disorder. There are currently no treatments that cure Parkinson’s disease (PD) or slow its progression. There is therefore an urgent need for ...
    • The dependency of image quality on acquisition protocol and image processing in chest tomosynthesis 

      Jadidi, Masoud (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-02)
      The digital tomosynthesis (DTS) technique is a next generation of the old tomography technique, the use of which has been extended during the past decade. The interest in this technique has increased more and more in ...
    • Teamarbete och informationsöverföring inom perioperativ vård : operationssjuksköterskans perspektiv 

      Sandelin, Annika (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-06-12)
      Bakgrund: Ett säkert genomförande av en kirurgisk intervention fordrar professionell kompetens, med såväl tekniska som icke-tekniska färdigheter. En säker vård kräver adekvat information om patienten och planerade ...
    • Har den kliniska obduktionen spelat ut sin roll? 

      Rosendahl, Anders (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2019-05-03)
      Background: The total number of autopsies has dropped during the last decades to less than a quarter of the number during the 1980-ies. We studied the consequences of a decrease in the autopsy frequency for the accuracy ...
    • Home-cage monitoring of mouse behaviours across life-span 

      Pernold, Karin (Inst för neurovetenskap / Dept of Neuroscience, 2019-04-25)
      Background and aim: The academic research involving animal testing is struggling with problems of reproducibility and a few of the specific reasons pointed out are for example insufficient reporting of animal strains and ...
    • The importance of thyroid function for female reproduction 

      Akram, Frida Hosseini (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2019-02-18)
      Background: Thyroid dysfunction is one of the most common endocrine disorder. Thyroid dysfunction affects the female reproductive system and can be manifested by menstrual irregularities, pregnancy loss and infertility. ...
    • Diabetic foot care in Sweden 

      Wennberg, Linda (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-02-11)
      Diabetes mellitus (DM) is a growing global disorder associated with several complications that include micro- and macrovascular disturbances. Conditions affecting the foot make up one of the major complications of the ...
    • Patient experiences and the influence on health literacy and self-care using mHealth to manage symptoms during radiotherapy for prostate cancer 

      Christiansen, Mats (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-02-01)
      Introduction: Prostate cancer is a diagnosis that can affect the men’s quality of life both due to the symptoms related to the disease and the treatment the men receive. Treatment with radiotherapy for prostate cancer ...
    • From nucleus to mitochondria : a ubiquitination study 

      Richard, Thibaud JC (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2019-01-18)
      Ubiquitination is a post-translational modification achieved by an enzymatic cascade. This post-translational modification is involved in many crucial cellular processes across different cellular compartments such as ...
    • Patient and organisational perspectives of initial trauma care 

      Granström, Anna (Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2018-10-18)
      Physical trauma is one of the major causes of death and disability worldwide. In Sweden a similar pattern can be seen despite having a well-organised health-care system. Improvements in trauma care can increase survival ...
    • Jämlik vård ur ett prehospitalt akutsjukvårdsperspektiv 

      Alm Pfrunder, Annika (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2018-05-23)
      Bakgrund: Målsättningen för jämlik vård är enligt Världshälsoorganisationen (WHO) och Hälso- och sjukvårdslagen (HSL) 1982:763 att hälso- och sjukvården ska ge god hälsa och en vård på lika villkor för hela befolkningen, ...
    • Vaccine safety, vaccine effectiveness and other determinants for successful immunisation programmes 

      Lamb, Favelle (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-05-11)
      The studies in this thesis examined several key determinants for successful uptake of vaccinations in the Nordic countries, with focus on vaccine safety and vaccine effectiveness. In study I, we investigated whether ...