• MRI in multiple sclerosis : early detection, cortical lesions and gadolinium retention 

  Forslin, Yngve (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-03-21)

  Background: Multiple sclerosis (MS) is a common neuroinflammatory and -degenerative disease. Magnetic Resonance Imaging (MRI) facilitates the diagnosis of MS, providing means to initiate early treatment and improving the ...

• Perinatal snus exposure and cardiovascular function in the child 

  Nordenstam, Felicia (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)

  Maternal use of smoking tobacco during pregnancy is one of the most important preventable risk factors during pregnancy. Maternal smoking is associated with alterations in autonomic cardiac control and long-term cardiovascular ...

• Neonatal thrombocytopenia : from bleeding risk to new therapies on the horizon 

  Deschmann, Emöke (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)

  Background: Thrombocytopenia is common in the Neonatal Intensive Care Unit and if severe, it is treated with platelet transfusions to prevent bleeding. Previous studies found a weak correlation between thrombocytopenia and ...

• Lung function measured with SPECT in infants and children with bronchopulmonary dysplasia : correlation with respiratory management and clinical grading 

  Kjellberg, Malin (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)

  Chronic lung disease, bronchopulmonary dysplasia (BPD) is a common and severe complication among extremely preterm born infants and infants with lung hypoplasia. Clinical grading of BPD is performed at 36 weeks postmenstrual ...

• A neuroimaging perspective on the emotional sleepy brain 

  Tamm, Sandra (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-03-15)

  Sleep has been shown to be important for a number of emotional functions. Brain correlates to the effect of sleep deprivation on emotion have been studied in the last decades and increased amygdala reactivity has been ...

• Regeneration and neural circuits in the spinal cord : an imaging study on zebrafish 

  Ellström Dehnisch, Ivar (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2019-03-14)

  The reversal of spinal cord injury (SCI) and its devastating effect on voluntary control is one of the most provocative challenges in neuroscience research. Preclinical and clinical research has for a very long time tried ...

• Elucidation of the cell signaling pathways mediating innate immunity and host-pathogen interactions 

  Nabar, Neel (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2019-03-14)

  The ability to generate a robust immune response is integral to organismal homeostasis. Cells of the innate immune system are considered the first responders of immunity, and are therefore responsible for sensing both ...

• ReWork-Stroke : content and experiences of a person-centred rehabilitation programme for return to work after stroke 

  Öst Nilsson, Annika (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-03-14)

  The process of return to work (RTW) after stroke is complex, less than half of those having stroke in working ages RTW. Guidelines targeting RTW in Sweden is lacking. The overall aim was to enhance the knowledge ...

• Investigations into the distribution and function of nucleobindin 1 

  Williams, Paul (Inst för neurovetenskap / Dept of Neuroscience, 2019-03-14)

  The nucleobindin proteins (NUCB1 and NUCB2) are both characterised by DNA- and calcium-binding motifs. The functionality of these motifs has been demonstrated, but has not yet led to the identification of a role for either ...

• Adults with cystic fibrosis : mental health and patient experiences of the CF treatment 

  Backström Eriksson, Lena (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-03-14)

  Background: Cystic fibrosis (CF) is an autosomal recessive inherited, life shortening multi organ disease most typically affecting the respiratory system and the gastrointestinal tract. In recent decades progresses in ...

• Identification of novel factors regulating human adipocyte function and their link to metabolic health 

  Petrus, Paul (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2019-03-13)

  The white adipose tissue (WAT) regulates energy homeostasis by storing and releasing energy in the form of fat as well as functioning as an endocrine organ secreting a myriad of different peptides. The heterogeneous WAT ...

• Transarterial chemoembolization in primary liver and kidney malignancies 

  Karalli, Amar (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-12)

  Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and the most current treatment for unresectable hepatocellular carcinoma is transarterial chemoembolization using drug-eluting beads (DEB-TACE). The ...

• Infections in patients with chronic kidney disease : patterns, outcomes and the role of vitamin D for future prevention 

  Su, Guobin (Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2019-03-11)

  Background: Chronic kidney disease (CKD) is increasingly recognized as a global public health problem. Patients with CKD are at high risk of infections. Frequent episodes of infections with greater use of antibiotics ...

• Cooperativity between MYC and other oncogenic factors : implications for tumorigenesis and targeting of MYC 

  Zakaria, Siti Mariam (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2019-03-08)

  Normal cell homeostasis in a tissue requires a delicate balance between cell growth, maintenance and death, tightly controlled by an intricate interplay between proto-oncogenes and tumor suppressor genes. When the balance ...

• Mild traumatic brain injury : antecedents and aftermath 

  Oldenburg, Christian (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2019-03-08)

  Mild Traumatic Brain Injury (mTBI) is a frequent, trauma-induced injury, associated with loss of consciousness and/or memory loss for the injury event. Injured individuals experience a wide range of somatic symptoms (e.g. ...

• Treatment of distal radius fractures : clinical outcome, regional variation and health economics 

  Saving, Jenny (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-03-08)

  A distal radius fracture (DRF) remains the most common fracture encountered in health care. DRFs have traditionally been treated with a plaster or surgically with percutaneous methods. Since the end of the 20th century, ...

• Oral mucosa keratinocytes and their exosomes for epithelial tissue regeneration 

  Sjöqvist, Sebastian (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)

  Early tumors, including high grade dysplasia and intramucosal invasive cancer, of the esophagus can today be removed using endoscopic resection, often using a technique called endoscopic submucosal dissection (ESD). This ...

• Medical decision-making capacity among geriatric patients with and without dementia : communication-based approaches for assessment and facilitation 

  Thalén, Liv (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)

  Introduction: Medical decision-making capacity concerns a patient’s cognitive abilities to make autonomous decisions regarding own person in medical contexts such as to choose treatment or accept/decline participation ...

• Life after extracorporeal membrane oxygenation : long-term survival and quality of life 

  von Bahr, Viktor (Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2019-03-07)

  Background: The use of Extracorporeal membrane oxygenation (ECMO) has steadily increased in the last decades and has evolved in several ways. From originally being a means to support the neonatal patient with respiratory ...

• What makes cognitive behavior therapy work? An investigation of psychological and inflammatory processes 

  Santoft, Fredrik (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-03-06)

  Background: Common mental disorders (CMDs; anxiety disorders, depression, insomnia and stress-related disorders) cause significant suffering, reduced functioning and impaired quality of life. Cognitive behavior therapy ...

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