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Recent Submissions

  • Tailoring and standardizing the assessment of ability and disability in ADHD and autism : the development of WHO ICF core sets 

    Mahdi, Soheil (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-29)
    The concept of health has evolved over time and is today considered a multidimensional construct that involves not only absence of impairments or pathologies, but also quality of life and individual functioning. This ...
  • Effects of DNA damage and vesicular exchange in P. falciparum 

    Hjelmqvist, Daisy (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2019-05-28)
    Plasmodium falciparum causes human malaria and is a global leading cause of mortality from parasitic infections. While decades of concerted effort has yielded significant result in reducing the endemicity, there is evidence ...
  • Post abortion care in Uganda : improving access and quality of care through task sharing and exploring the perspectives of young women and healthcare providers 

    Cleeve, Amanda (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-28)
    BACKGROUND. Unsafe abortions in Uganda continue to cause significant harm to women’s health and lives and pose a heavy burden on the health system. The consistent shortage and maldistribution of healthcare providers impede ...
  • Roles of SNAP-25 isoforms in activity-dependent long-term synaptic plasticity 

    Irfan, Muhammad (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-05-28)
    SNARE proteins, SNAP-25, syntaxin 1A and VAMP2 constitute the functional units which join together to form the core SNARE complex. The SNARE complex carries out the vital function of membrane fusion of intracellular vesicles ...
  • Regulation of calcium flux by activating and inhibitory receptor crosstalk in NK cells 

    Ganesan, Sridharan (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2019-05-27)
    The birth of a new born child kicks off the immune system to be on call and to respond promptly to threats from the environment. Natural Killer cells, classified as a member of the innate lymphoid cell family, express ...
  • Endocrine and paracrine factors related to pregnancy and infertility 

    Hosseini Akram, Frida (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2019-05-24)
    Unexplained infertility, one of the common gynecological disorders, affecting 10 to 15 % of women worldwide. Recurrent pregnancy loss affects approximately 1 to 3 % of pregnant women with an unknown etiology in 50 % of ...
  • The development of the human immune system during the first five years of life 

    Olin, Axel (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-24)
    Systems immunology is a scientific field combining high-throughput analytic technologies and integrative data analysis to study the immune system from a holistic perspective. As the immune system is a complex integrated ...
  • Educational leadership in health professions education 

    Sundberg, Kristina (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2019-05-24)
    The aim of this thesis was to explore perceptions and experiences of educational leaders leading educational change and development in health professions and interprofessional education. The sensitising concepts of the ...
  • The role of new ultrasound modalities to refine the diagnostic workup on women with cervical carcinoma 

    Pálsdóttir, Kolbrún (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-24)
    Background: Cervical cancer is the fourth most common female cancer in the world and has traditionally been clinically staged not including imaging. Despite that, clinicians depend on diagnostic imaging in the management ...
  • Airborne occupational exposures and risk of developing rheumatoid arthritis 

    Ilar, Anna (Institutet för miljömedicin / Institute of Environmental Medicine, 2019-05-24)
    Background: Rheumatoid Arthritis (RA) is an autoimmune, inflammatory disease with multifaceted aetiology. Cigarette smoke is the strongest environmental risk factor of RA, and research suggests that airborne exposures may ...
  • Inter-hospital transports of critically ill children 

    Hannegård Hamrin, Tova (Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2019-05-24)
    There is an increasing need for inter-hospital transports of seriously ill children as a result of centralization of intensive care for children to dedicated pediatric intensive care units (PICU). This thesis has explored ...
  • Molecular mechanisms of cardiovascular calcification 

    Carracedo Ortiz, Miguel (Inst för medicin, Solna / Dept of Medicine, Solna, 2019-05-23)
    Cardiovascular calcification is a pathophysiological process characterized by the deposition of calcium-phosphate crystals in the arteries and the leaflets of the heart valves. In the arteries calcification causes arterial ...
  • Cadasil : a pure model for studying cerebral small vessel disease 

    Panahi, Mahmod (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-05-23)
    Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is caused by a mutation on the NOTCH3 gene. The pathological driver behind this disease is the loss of vascular smooth ...
  • Effects of BCG-treatment on urinary bladder cancer with focus on nitric oxide 

    Thiel, Tomas (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2019-05-23)
    Intravesical Bacillus Calmette-Guérin is used as a single agent or adjuvant therapy in the treatment of non-muscle invasive bladder cancer. In spite being one of the most efficient immunological treatments in cancer, BCG ...
  • On GABAergic interneuron diversity and maturation 

    Munguba, Hermany (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2019-05-23)
    GABAergic interneurons provide finely, distinct styles of inhibition granted by their unique targeting preferences, molecular profiles, and morphological silhouettes. A central quest of my thesis was to explore what ...
  • To give birth in water 

    Úlfsdóttir, Hanna (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-05-23)
    The aim of this thesis was to study waterbirth in a Swedish context and to bring focus on clinical outcomes and women’s experiences associated with waterbirth. The literature describes advantages for women giving birth ...
  • Pediatric acute neuropsychiatric syndrome : diagnosis, biomarkers and treatment 

    Hesselmark, Eva (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-05-23)
    Background: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) and Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) are proposed diagnoses combining a clinical picture ...
  • Identification of the adult septic patient in the prehospital and emergency department setting 

    Wallgren, Ulrika M (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-05-22)
    Sepsis is one of the most urgent conditions encountered within emergency care but is often difficult to recognize due to its non-specific presentations. One third of the patients lack the classic sign of infection; i.e. ...
  • Music therapy : an intervention effecting quality of life and health in children going through hematopoietic stem cell transplantation 

    Uggla, Lena (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-05-21)
    Hematopoietic stem cell transplantation (HSCT) is an established treatment for several types of leukemic, hematopoietic, and metabolic diseases. The child is isolated during 4-6 weeks, followed by extensive follow-up for ...
  • Possibilities of dried blood spots as a matrix in therapeutic drug monitoring of antiepileptic drugs in children 

    Linder, Camilla (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2019-05-21)
    For children with epilepsy, therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for treatment. TDM monitoring requires two visits to a health care unit, first for collection of the blood sample ...

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