Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience: Recent submissions
Now showing items 61-80 of 771
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Harm from others’ drinking : reported negative experiences and predictors in general population surveys
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-25)Background: Alcohol consumption is among the top risk factors for ill health and premature death and can also lead to a range of problems in relation to other people such as family members, friends, co-workers, and among ... -
Validation of a novel PET imaging marker for dopaminergic degeneration in Parkinson’s disease patients
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-25)Background: There is a need for an objective disease progression marker for Parkinson’s disease (PD). DAT measurement with PET-radioligand [18F]FE-PE2I has so far shown to be promising with its favorable kinetics, low ... -
Patient-initiated brief admission for emotional instability and self-harm
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-24)Background: Previous studies have reported negative experiences of psychiatric inpatient care for patients with emotional instability and self-harm. A novel intervention called patient-initiated brief admission (PIBA) has ... -
Psychological factors, sickness behavior and inflammatory biomarkers in longstanding pain
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-24)Background: Longstanding pain affects a large number of adults worldwide. In addition to pain, several factors like depression, anxiety, and insomnia can also affect disability and quality of life. Some patients improve ... -
Improving access and outcomes in the treatment of obsessive-compulsive disorder
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-17)Effective psychological treatments exist for obsessive-compulsive disorder (OCD) in the form of cognitive behaviour therapy (CBT), but access is limited and adaptations are needed for groups of patients, for example ... -
Biomarkers and viral risk factors in multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-12)Multiple sclerosis (MS) is a chronic inflammatory disease resulting in axonal injury and demyelination of nerve fibers in the central nervous system. The causal factor and pathological mechanisms governing disease progression ... -
Mental health in women with polycystic ovary syndrome
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-04)Polycystic Ovary Syndrome (PCOS) is the most common hyperandrogenic condition in women. It is associated with several adverse health outcomes as subfertility, obesity, the metabolic syndrome, and skin issues. PCOS can be ... -
Studies on eye movements in Parkinson's disease
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-05-03)Heterogeneity in Parkinson’s Disease (PD) phenotype and genotype is probably the main reason why, despite the abundance of biomarkers, we still lack a robust method for diagnosis and prognosis, besides clinical evaluation. ... -
Psychological factors and communication skills training in intensive care medical staff
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-28)Background: Intensive care settings have been shown to present a demanding work setting with health related and work-related consequences for intensive care medical staff. The health-related consequences observed are high ... -
Improving access to behaviour therapy for young people with Tourette syndrome
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-26)Tourette syndrome (TS) and Chronic Tic Disorder (CTD) are childhood-onset neurodevelopmental disorders characterised by motor and vocal tics. Treatment guidelines recommend behaviour therapy (BT) as the first-line treatment ... -
Feasibility, safety, and diagnostic potential of endomyocardial micro-biopsies
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-22)Endomyocardial biopsy (EMB) is considered a reference method for diagnosis of several cardiac diseases, but the method is limited by significant complication risks and relatively poor sensitivity. Although attempts have ... -
Acceptance and commitment therapy for autism spectrum disorder : evaluation of feasibility, effectiveness, and validity of a novel contextual behavioral treatment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-21)Background: Autism spectrum disorder (ASD) is neurodevelopmental condition, characterized by challenges in reciprocal social behavior, restricted and repetitive behaviors and interests, and sensory hyper- and hyposensitivity. ... -
Neural processes underpinning pain perception : genetic, temporal, and behavioral factors
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-20)Pain is an alarm system – warning us of dangers in the environment – yet becomes problematic when it transitions into chronic pain. It is defined, according to the International Association of Pain as “An unpleasant sensory ... -
Peripheral neuropathy and altered cobalamin metabolism in Parkinson's disease and other movement disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-20)Peripheral neuropathy is a disorder of the peripheral nervous system (PNS) that may carry different underlying aetiologies. Studies have suggested PNS involvement may be prevalent in neurological diseases that traditionally ... -
Swedish universities scales of personality : relationship to other personality instruments, patient-control differences and longitudinal stability in schizophrenia and related disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-12)Objective: Schizophrenia and related disorders are often severe and chronic. They could also cause a lasting change in the life situation of the affected individual. Personality is an aspect that can affect symptoms and ... -
Regulation of monoaminergic functions by GPCRs with a special emphasis on mental and movement disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-11)Dysfunction of the brain’s monoaminergic system has been implicated in many human neurological and psychiatric disorders, such as Parkinson’s disease (PD), major depressive disorder (MDD) and schizophrenia. The monoamines ... -
Perinatal risk factors for mental disorders in the offspring and in their mothers
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-06)Mental disorders are common in the population, but their etiology remains largely unknown. Early-life factors have been hypothesized to be potential risk factors; however, current evidence is conflicting and incomplete. ... -
Work disability, economic situation, and societal costs of multiple sclerosis in Sweden
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-04-04)Background: Multiple sclerosis (MS) affects many aspects of life and often leads to a reduction in an individual’s work capacity. This reduction, referred to as work disability, may lead to the use of social protections ... -
Congenital cataract and contact lenses
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-03-29)Purpose: Having a child with congenital cataract is associated with a huge responsibility for the parents in terms of the outcome of their child’s visual development. If the cataract is not removed the condition will lead ... -
The role of pain modulation in non-suicidal self-injury
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-03-18)Individuals with non-suicidal self-injury (NSSI) behavior tend to report feeling little or no pain when they self-injure. Moreover, in laboratory studies the NSSI population tends to demonstrate reduced sensitivity to ...