Doktorsavhandlingar / Doctoral Theses - K6 (KBH): Recent submissions
Now showing items 121-140 of 487
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Lung function measured with SPECT in infants and children with bronchopulmonary dysplasia : correlation with respiratory management and clinical grading
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)Chronic lung disease, bronchopulmonary dysplasia (BPD) is a common and severe complication among extremely preterm born infants and infants with lung hypoplasia. Clinical grading of BPD is performed at 36 weeks postmenstrual ... -
Long-term effects of pre- and postnatal glucocorticoid treatment in congenital adrenal hyperplasia
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-02-15)Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder mostly caused by mutations in the CYP21A2 gene leading to impaired production of cortisol and aldosterone. Precursors in the steroidogenic pathway are ... -
More than a foot : gait, gross motor skills, neurodevelopmental difficulties and health-related quality of life in children with idiopathic clubfoot
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-01-17)Introduction: Idiopathic clubfoot (IC) is one of the most common congenital musculoskeletal deformities and can affect one or both feet of the child. However, knowledge beyond the structural deformity is still limited. ... -
Communication over language barriers in paediatric oncology care : a prerequisite for equity in care
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-11-22)Background: Out of Sweden's more than two million children under the age of eighteen, 23% have a foreign background, which means that every fourth child has a foreign background. We know that migration and the mixed ... -
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-11-15)Surgery is standard treatment for early stage endometrial cancer (EC), the most common gynaecological malignancy in developed countries. Traditionally, surgery has been performed by laparotomy (LT). Comprehensive surgical ... -
Muscle composition, reach, physical activity and botulinum toxin treatment in children with cerebral palsy
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-11-09)Cerebral palsy (CP), the most common cause of movement disorders and physical disability in children all over the world, is caused by an injury to the developing brain. Although this injury is not progressive, the ... -
Auxological tools for following growth in extreme short stature and for evaluating growth promoting interventions
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-11-07)Growth charts are inevitable tools for following children in clinical practice and also when evaluating growth promoting therapy. Growth is a concern especially for families to children of extreme short stature such as in ... -
Children with low anorectal malformations and their parents : quality of life, physical and psychosocial function
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-10-31)Anorectal malformations (ARM) are congenital anomalies affecting 1 in 3 000 births. The malformation varies from very minor to complex and can be divided in to low, intermediate, and high form of ARM. Children with a low ... -
In vitro models aiming for fertility preservation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-10-11)Fertility preservation is considered a great hope to people suffering from infertility as a consequence of developmental or genetic cause, a disease itself or its treatments sequelae. In vitro models are fundamental to ... -
Cardiopulmonary function, quality of life and effects of exercise in children and adolescents with Fontan circulation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-10-03)Background: Survival of children and adolescents with Fontan circulation has increased over the last decades, and today a large majority survive to adult age. There is increasing concern regarding these children’s impaired ... -
von Willebrand disease in women : heavy menstrual bleeding and obstetrical bleeding
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-09-25)Von Willebrand disease is the most common inherited bleeding disorder worldwide with a prevalence, reaching 1% of general population. vWD is equally distributed between genders. However, vWD-affected females experience ... -
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-17)Prematurity affects more than 10% of infants worldwide and is the main reason for neonatal mortality. Improvements in neonatal care have led to higher survival rates into adulthood. Adverse events during organogenesis and ... -
Optic nerve hypoplasia in children : prevalence, associated disorders and genetic causes
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-10)Optic nerve hypoplasia (ONH) is a congenital ocular malformation with a thin optic nerve in one or both eyes. ONH has been associated with neurodevelopmental disorders and pituitary dysfunction, but the prevalence of these ... -
Novel culture systems to model testicular function and organization
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-08-02)In vitro systems to model the testicular microenvironment are required to study physiology and pathology of the testis, the gonadotoxic effect of environmental and pharmaceutical chemicals, as well as to explore the ... -
Psychological aspects in differences / disorders of sex development
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-07-24)Background: Sex differentiation depends on a complex set of molecular events. These are at one point initiated by SRY gene expression and involve gene transcription, which in turn can be affected by the prescence or absence ... -
Extremely preterm birth : brain imaging and outcome at early school-age
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-05-09)There has been a dramatic increase in the survival of extremely preterm children over the last decades, and the awareness of the consequences of extremely preterm birth on the developing brain is increasing. This thesis ... -
Late effects and health-related outcomes after allogeneic hematopoietic stem cell transplantation in childhood
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-27)Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established treatment for many acquired or congenital disorders of the hematopoietic system. For some patients it may be the only curative option. Most ... -
Local anaesthesia in term- and preterm infants
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-24)Background: Local anaesthesia is known to be a safe and effective method for postoperative pain management in adults and children. This convenient method is however rarely used in term and preterm infants, despite its ... -
Epidemiologic studies on acute appendicitis in children
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-12)Acute appendicitis is the most common surgical emergency in children. A considerable effort has been made to develop and improve treatment and outcomes. A PubMed search yields over 20 000 publications on appendicitis. ... -
Prevention of cervical cancer in countries with high and low incidence of the disease
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2018-04-11)Cervical cancer is to a large extent a preventable disease, through prophylactic human papillomavirus (HPV) vaccination and cervical cancer screening. Still, it is the second most common cancer among women in Argentina, ...