Doktorsavhandlingar / Doctoral Theses - K6 (KBH): Recent submissions
Now showing items 101-120 of 487
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Microglia in the juvenile brain after cranial irradiation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-12-19)Radiotherapy is used to treat pediatric brain tumors and is often accompanied with debilitating late effects, such as cognitive decline. However, the mechanisms are poorly understood, and consequently there is still no ... -
Pelvic floor complications after vaginal birth : short- and long-term consequenses for primiparous women in Sweden
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-11-15)Women giving birth to their first baby often sustain some form of perineal injury. These injuries can cause short- and long-term pelvic floor dysfunction symptoms and may affect their health. This thesis focuses on a sample ... -
Increasing uptake of long-acting reversible contraception : LARC
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-11-12)BACKGROUND: Unintended pregnancies are an inexhaustible source to life-changing decisions and events for individuals and result in enormous costs for societies having to deal with maternal health services, deliveries, ... -
Unprovoked seizures in children : incidence, neurodevelopmental comorbidities and treatment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-11-07)Epilepsy is considered to be the neurological disease that gives the largest burden of disease in children. It is a heterogeneous disease with very diverse consequences in the lives of the patient. Comorbidities with other ... -
Antiapoptotic effect of ouabain in renal cells exposed to toxic glucose levels
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-11-06)Diabetes mellitus is a group of metabolic diseases that causes enormous social and economic burden. The kidney is the filtration organ that produces urine and is the primary target of diabetic complications, a condition ... -
Morphological variants in neurodevelopmental disorders
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-10-25)Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are diagnosed in a significant minority of children, adolescents, and adults worldwide. ... -
Prevention of growth failure caused by glucocorticoids and inflammation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-10-24)Longitudinal bone growth is a complex process that takes place in the growth plate, and normal growth is dependent on a precise balance of several endocrine and paracrine factors. Growth impairment is common in children ... -
Perinatal mental health among young women in urban China
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-10-18)In order to reach the WHO’s Sustainable Development Goals relating to maternal and infant health, maternal mental health preconditional needs to be addressed. The purpose of the thesis project was to explore how Shanghai ... -
Laminins in stemness and germ cell development in human
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-10-04)Stem cell niches regulate the fine balance between self-renewal and differentiation of various stem cells. Although crucial hallmarks of stem cell niches, such as the mechanical signalling, neural inputs communicating ... -
Metabolic effects and long-term safety of childhood growth hormone treatment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-09-16)The overall aim of this thesis was to investigate the metabolic effects and long-term safety of childhood growth hormone (GH) treatment. In order to achieve this aim, the different projects consist of a two-part clinical ... -
Tailoring and standardizing the assessment of ability and disability in ADHD and autism : the development of WHO ICF core sets
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-29)The concept of health has evolved over time and is today considered a multidimensional construct that involves not only absence of impairments or pathologies, but also quality of life and individual functioning. This ... -
Post abortion care in Uganda : improving access and quality of care through task sharing and exploring the perspectives of young women and healthcare providers
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-28)BACKGROUND. Unsafe abortions in Uganda continue to cause significant harm to women’s health and lives and pose a heavy burden on the health system. The consistent shortage and maldistribution of healthcare providers impede ... -
The development of the human immune system during the first five years of life
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-24)Systems immunology is a scientific field combining high-throughput analytic technologies and integrative data analysis to study the immune system from a holistic perspective. As the immune system is a complex integrated ... -
The role of new ultrasound modalities to refine the diagnostic workup on women with cervical carcinoma
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-24)Background: Cervical cancer is the fourth most common female cancer in the world and has traditionally been clinically staged not including imaging. Despite that, clinicians depend on diagnostic imaging in the management ... -
Hand assessment for infants : development, internal scale validity, reliability and normative reference values
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-20)Infants use their hands to explore the world and neural event in the developing brain can affect the infant’s ability to use the hands. An infant that has suffered a brain lesion may show clinical signs of unilateral ... -
Molecular characterisation and prophylactic treatment strategies among women with benign gynecological disorders
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-05-20)Background: Female reproduction is controlled by hormones in a timed and well-coordinated manner by the hypothalamus-pituitary-ovarian axis. In response to the ovarian hormones such as estrogen, and progesterone, endometrium, ... -
Patent ductus arteriosus in extremely preterm infants : characteristics, risk factors and treatment decisions
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-04-23)Survival rates in infants born extremely preterm, before 28 weeks of gestation, are increasing and the focus has shifted towards decreasing morbidites after extremely preterm birth and promoting life-long health for the ... -
Chlamydia among youth in Stockholm : testing habits and evaluation of a mobile phone intervention to promote safe sexual practices
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-04-10)Background: The World Health Organization (WHO) estimates that 350 million new cases of curable sexually transmitted infections (STIs) occur each year. Prevention of STIs include both primary and secondary prevention ... -
Perinatal snus exposure and cardiovascular function in the child
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)Maternal use of smoking tobacco during pregnancy is one of the most important preventable risk factors during pregnancy. Maternal smoking is associated with alterations in autonomic cardiac control and long-term cardiovascular ... -
Neonatal thrombocytopenia : from bleeding risk to new therapies on the horizon
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2019-03-15)Background: Thrombocytopenia is common in the Neonatal Intensive Care Unit and if severe, it is treated with platelet transfusions to prevent bleeding. Previous studies found a weak correlation between thrombocytopenia and ...