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Recent submissions

  • Atopic dermatitis in adults : epidemiological studies of comorbidity and studies of patients on systemic treatment 

    Ivert, Lina (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-06-01)
    Background: Atopic dermatitis (AD) is one of the most common chronic skin disorders globally. It is an itchy inflammatory skin disease that can have a detrimental impact on health-related quality of life. In recent years, ...
  • Pharmacoepidemiologic studies of drug safety in pediatric chronic inflammatory disease 

    Wintzell, Viktor (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-26)
    Safety evidence for use of pharmaceutical drugs in children, including treatments for serious conditions such as chronic inflammatory diseases, is generally scarce. Off-label use is common and clinicians need to rely on ...
  • Risk factors and comorbidity in primary Sjögren’s syndrome 

    Mofors, Johannes (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-21)
    Primary Sjögren’s syndrome is an autoimmune disease, in which the immune system targets the exocrine glands. The disease is characterized by inflammation and dysfunction of the salivary and lacrimal glands, leading to ...
  • Immunopeptidomics and autoantigens of interstitial lung diseases 

    Wiklundh, Emil (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-21)
    We investigate Sarcoidosis and Idiopathic Pulmonary Fibrosis, IPF, to find markers for early fibrosis development. The aetiologies for both diseases are unknown and there is no specific treatment, moreover, there is a lack ...
  • Psoriasis : observational studies on clinical course, economic burden and treatment 

    Svedbom, Axel (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-11)
    Better understanding of long-term prognosis, clinical course, comorbidities, economic burden, and treatment of psoriasis, can improve care of patients with the disease and may inform decisions on resource allocation, ...
  • Socioeconomic status and myocardial infarction : influence on secondary prevention and prognosis 

    Ohm, Joel (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-11)
    Background and Aims In the wealth of research undertaken on myocardial infarctions (MIs), secondary prevention is less well studied. Incidence and death from MI have declined substantially in the past decades due to the ...
  • Impact of genetic and environmental factors in intestinal inflammation 

    Diaz Perez, Oscar Eduardo (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-07)
    The gastrointestinal tract, is continuously exposed to a wide variety of stimuli, including dietary-derived metabolites, environmental compounds and the microbiota. Since these antigens can be beneficial or detrimental ...
  • Thrombotic and cardiac disease in the antiphospholipid syndrome 

    Grosso, Giorgia (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-04-16)
    The antiphospholipid syndrome (APS) is a highly heterogeneous disease that presents with obstetric complications and/or thromboembolic events that can hit any side of the vascular tree in an unpredictable way. The common ...
  • Neural control of inflammation 

    Caravaca, April S. (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-31)
    Pioneering research on neural control of inflammation has paved the way for new and exciting developments in the growing field of bioelectronic medicine. In the past couple of decades, pre-clinical research on the role ...
  • Immunopathogenic mechanisms in primary Sjögren’s syndrome 

    Björk, Albin (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-30)
    Primary Sjögren’s syndrome is a systemic autoimmune disease primarily affecting salivary and lacrimal glands, but patients may also have other organ involvement. Development of Sjögren’s syndrome has been associated with ...
  • Exploring lymphocyte subsets, autoantibodies and the effect of B cell targeted therapies in rheumatic diseases 

    Sippl, Natalie (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-12)
    Nowadays, around 100 different diseases sort under the umbrella of rheumatic diseases(1). They involve different mechanisms and symptoms engaging joints, tendons, ligaments, bones, muscles but also vital organs like the ...
  • Sex and gender aspects in drug utilization 

    Loikas, Desirée (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-04)
    Drug prescribing is one of the most important processes in healthcare and drugs are also commonly used in the population. Drug use differs between men and women and descriptive reports of sex differences in drug use have ...
  • Molecular insights into the pathogenesis of b-cell and myeloid malignancies : therapeutic implications 

    Xia, Chuanyou (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-03-03)
    Hematological malignancies originate from hematopoietic cells in the bone marrow or the lymphatic system. In this thesis, I study the molecular pathogenesis of Hodgkin lymphoma (HL), mantle cell lymphoma (MCL), and ...
  • Demand and capacity imbalance in the emergency department, and patient outcomes 

    Ugglas, Björn af (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-02-16)
    Background An emergency department (ED) is always open and continuously needs to balance the inflow and demand for emergency service with available capacity. When demand exceeds the available capacity of an ED, it ...
  • Epidemiological aspects of sarcoidosis : risk factors and long-term consequences 

    Rossides, Marios (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-01-27)
    Sarcoidosis is a systemic inflammatory disease of unknown etiology in which granulomatous lesions form mostly in the lungs and the lymphatic system of patients. Although more than a century has passed since sarcoidosis ...
  • Inflammatory arthritis and pregnancy 

    Remaeus, Katarina (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-01-14)
    The aim of this thesis was to add to the existing knowledge of how inflammatory arthritis disease affects pregnancy outcomes. In particular, the aim was to describe and study the effects of a diagnosis of juvenile idiopathic ...
  • Long-term survival and survivorship in non-Hodgkin lymphoma patients in Sweden 

    Ekberg, Sara (Inst för medicin, Solna / Dept of Medicine, Solna, 2020-12-11)
    Non-Hodgkin lymphoma (NHL) is one of the top ten most common cancer types in Sweden. Although sometimes referred to as one disease, NHL is truly an umbrella term representing a heterogeneous group of diseases with varying ...
  • Common medications in the risk and prognosis of lymphoid neoplasms and epidemiology of primary CNS lymphoma 

    Brånvall, Elsa (Inst för medicin, Solna / Dept of Medicine, Solna, 2020-11-30)
    Lymphoid neoplasms are malignancies arising from the lymphocyte, and include lymphoma subtypes, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). It is a heterogenous group of diseases, with different molecular ...
  • Dispatch of lay responders to out-of-hospital cardiac arrests 

    Berglund, Ellinor (Inst för medicin, Solna / Dept of Medicine, Solna, 2020-11-27)
    Background and aim Out-of-hospital cardiac arrest (OHCA) remains a major public-health problem affecting around 300 000 Europeans each year. If treatment is not started within a couple of minutes the chances of ...
  • Genetics of systemic autoimmunity and comorbidities 

    Thorlacius, Guðný Ella (Inst för medicin, Solna / Dept of Medicine, Solna, 2020-11-26)
    Sjögren‘s syndrome (SS) is a systemic autoimmune disease that typically affects the salivary and lacrimal glands leading to dry eyes and dry mouth, but the patients may also have systemic involvement. Most patients with ...

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