RSS submission
 

Recent Submissions

  • Bone disease and diabetes mellitus 

    Ugarph-Morawski, Anna (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-09-01)
    Diabetes Mellitus (DM) and Osteoporosis (OP) frequently co-exist with advanced age and imply large health challenges worldwide. The last decades there has been a growing interest regarding fracture risk in DM. Currently ...
  • In vivo and in vitro studies of apolipoprotein CIII in diabetes 

    Åvall, Karin (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-08-23)
    Apolipoprotein CIII (apoCIII) is an important regulator of lipid metabolism and it is also known to have pro-inflammatory properties. From the point of view of diabetes it is interesting that both insulin deficiency and ...
  • Diagnosis, treatment and evaluation of chronic venous disease 

    Sinabulya, Helen (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-05-19)
    BACKGROUND AND AIMS: Varicose veins (VVs) are the most common manifestation of chronic venous disease (CVD) in the Western hemisphere. Recent research shows that the disease encompasses the global population and with ...
  • Psychological distress following oesophageal cancer treatment : is there a need for psychological support? 

    Hellstadius, Ylva (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-05-12)
    Oesophageal cancer is associated with a poor prognosis, an extensive treatment pathway and a difficult recovery process. Previous studies have shown that oesophageal cancer patients suffer from great physical impact of the ...
  • On preoperative treatment selection and magnetic resonance imaging in rectal cancer 

    Hansson Elliot, Anders (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-04-20)
    In Sweden, 2000 patients are diagnosed with rectal cancer annually. Developments in surgery have improved survival and the addition of preoperative radiotherapy (RT) or chemoradiotherapy (CRT) has reduced local recurrence ...
  • Appetite control : genetic, immunological and neurobiological aspects 

    Lindfors, Charlotte (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-31)
    The overall goal of this thesis is to develop a better understanding of the brain’s regulation of appetite, i.e. the hypothalamic regulation of hunger and satiety signals. The correct regulation of appetite is crucial, ...
  • Breast cancer in young women : aspects on mortality and local recurrence 

    Fredholm, Hanna (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-17)
    The general aim of the thesis was to gain increased insight into the long-term prognosis for young women with breast cancer. In a population-based cohort of 22,017 women with breast cancer, we studied prognosis by ...
  • Complicated peptic ulcer disease : prevention and treatment 

    Sverdén, Emma (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-15)
    Peptic ulcer is a common disease worldwide and its complications can cause serious clinical problems. While the incidence of uncomplicated peptic ulcer disease is decreasing, the incidence of more complex ulcer disease is ...
  • Identification and evaluation of novel prognostic genetic markers for childhood acute lymphoblastic leukemia 

    Ivanov Öfverholm, Ingegerd (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-02)
    Childhood acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer today. Due to advances in risk stratification and treatment, survival rates have increased drastically the last decades. Currently, ...
  • Evaluation of a metal-on-metal total hip arthroplasty 

    Dahlstrand, Henrik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-01-17)
    Background After the introduction of the Metasul system by Weber in 1988, total hip arthroplasty (THA) with metal-on-metal (MoM) bearings became increasingly popular in the 1990s. MoM bearings aimed to reduce the ...
  • Aspects of biliary tract cancer : incidence and reproductive risk factors 

    Kilander, Carl (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-21)
    Biliary tract cancer, including cancer of the extra-hepatic bile ducts, cancer of the Ampulla of Vater and gallbladder cancer, is a devastating disease with poor prognosis. The incidence of biliary tract cancer is ...
  • Preoperative local staging of prostate cancer : aspects on predictive models, magnetic resonance imaging and interdisciplinary teamwork 

    Jäderling, Fredrik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-15)
    In prostate cancer surgery the two issues at stake are the removal of the tumour on one hand and functional outcome i.e. urinary continence and sexual function on the other. A nerve preserving procedure will optimise the ...
  • Interplay between mitochondria, primary cilium, diabetes and its complications 

    Moruzzi, Noah (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-12)
    Diabetes is one of the major health problems of the 21st century. Dysfunction of the insulin secreting pancreatic β-cell together with insulin resistance is central to the pathogenesis of type 2 diabetes mellitus (T2DM). ...
  • Estrogen : molecular mechanisms of antidiabetic action 

    Al-Qahtani, Saad Misfer (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-29)
    The pathogenesis of metabolic syndrome is multifactorial and hormones play an essential role in its development. Estrogen loss in postmenopausal women has been linked to several features of metabolic syndrome, while estrogen ...
  • Outcome and refinements of gender confirming surgery 

    Sigurjónsson, Hannes (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-28)
    Introduction Gender dysphoria is a state in which the individual shows strong and persistent identification with the opposite sex. After thorough diagnostic assessment, the treatment includes gender confirming surgery ...
  • Imaging and modeling the cardiovascular system 

    Maksuti, Elira (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-21)
    Understanding cardiac pumping function is crucial to guiding diagnosis, predicting outcomes of interventions, and designing medical devices that interact with the cardiovascular system. In turn, better diagnostics and ...
  • Development of surgical techniques in craniofacial reconstruction 

    Neovius, Erik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-02)
    Introduction: Facial fractures are common and either the injury or the surgical treatment may cause sequelae including diplopia, visual loss, dystopia, enophthalmos, scarring, soft tissue affection and sensory disturbances. ...
  • Minimally invasive aortic valve replacement 

    Dalén, Magnus (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-10-31)
    Background: Minimally invasive aortic valve replacement (AVR) through a ministernotomy has been developed as an alternative approach to conventional full sternotomy AVR. During recent years, sutureless aortic ...
  • Monitoring the effect of anti- cancer treatment in uro- oncological malignancies with molecular imaging 

    Farnebo, Jacob (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-10-25)
    In the last decade, new therapies have changed the management of patients with metastatic renal cell carcinoma (mRCC) and metastatic castration resistant prostate cancer (mCRPC). Although new therapies have improved survival, ...
  • Factors potentially influencing pathogenetic mechanisms and hyperglycemia in pre-diabetes and type 2 diabetes : clinical studies in humans 

    Wagner, Henrik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-10-21)
    The pathogenetic mechanisms underlying type 2 diabetes (T2D) and prediabetes involve an interaction between β-cell dysfunction and insulin resistance (IR). The resulting hyperglycemia, as well as other clustered ...

View more