Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 81-100 of 531
-
Aspects on advanced procedures during endoscopic retrograde cholangiopancreatography (ERCP) for complex hepatobiliary disorders
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-02-08)Background: The rapid development in endoscopic technology and associated skills has led to an increase in more advanced procedures being performed during endoscopic retrograde cholangiopancreatography (ERCP). Knowledge ... -
Consequences of kidney dysfunction in the community : health care-based epidemiological studies from the Stockholm creatinine measurements (scream) project
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-01-26)Chronic kidney disease (CKD) is affecting an increasing share of the world’s population, and presents a global health problem. The prevalence of CKD in society and its implication for various health outcomes have been ... -
Differentiation of renal oncocytoma from renal cell carcinoma by means of ⁹⁹Tc-Sestamibi SPECT/CT
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-01-15)Purpose: An increasing body of literature indicates the beneficial role of [99m]Tc-Sestamibi SPECT/CT in the non-invasive differentiation of renal oncocytoma (RO) from renal cell carcinoma (RCC). This thesis presents a ... -
Experimental approaches and clinical opportunities in metabolic liver diseases
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-11-27)Metabolic liver diseases are uncommon individually, however, collectively they represent significant cause of morbidity and mortality globally. The liver has many diverse functions, such as; detoxification from hazardous ... -
Swedish children with moderate hearing loss : on the importance of monitoring auditory and early speech development the first three years
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-11-24)The overall aim of this thesis was to investigate the auditory and early speech development in a group of children born with moderate hearing loss (HL) who were fitted with hearing aids (HAs) before the age of 6 months, ... -
Coagulation in liver failure : the role of thromboelastometry and fibrinogen
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-11-06)Liver failure is undeniably accompanied by distortions of the coagulation system. The modern theory of coagulation in patients with compensated liver disease (acute or chronic) states that the coagulation system is in a ... -
Obesity in childhood : psychosocial consequences and premature mortality
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-10-21)Background: It is estimated that 91 million children worldwide will have obesity by 2025. Obesity in childhood is associated with increased risk of obesity in adulthood, psychosocial maladjustment, mental health problems, ... -
Uvulopalatopharyngoplasty : patient selection, long- term outcomes, and side effects
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-10-16)Uvulopalatopharyngoplasty (UPPP) is the most common surgical treatment for adult patients with obstructive sleep apnea (OSA). Its short-term efficacy, as measured through polysomnography, is well-established and has been ... -
Effects of age and stimulation strategies on cochlear implantation and a clinically feasible method for sound localization latency
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-28)Treating prelingual deafness with cochlear implants paves the way for spoken language development. Previous studies have shown that providing the intervention at six to 11 months is better than at 12-17 months. However, ... -
Energy expenditure and substrate utilization during critical illness
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-25)Background: Critical illness leads to major alterations in metabolism. The net result is a state where catabolism predominates over anabolism. The associated loss of lean body mass is significant and potentially harmful. ... -
Acute gastrointestinal graft-versus-host disease in allogeneic hematopoietic stem cell transplanted children and adolescents : clinical aspects of histopathological evaluation and risk factors
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-24)Background: Acute graft-versus-host disease (aGVHD), following allogeneic hematopoietic stem cell transplantation (HSCT), is a potentially life-threating condition. Gastrointestinal involvement of aGVHD (GI-aGVHD) affects ... -
Every bug counts : neonatal colonization and infection of Gram-negative bacilli : aspects on antibiotic resistance in Sweden and Ecuador
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-18)Neonatal infections caused by extended-spectrum beta-lactamase (ESBL)-producing Gramnegative bacilli are associated with high morbidity and mortality. In order to perform targeted preventive interventions against the impacts ... -
Fracture healing, functional outcome and health related quality of life in younger patients with a femoral neck fracture
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-08)Few prospective studies have investigated the patient-reported outcome measures (PROM) in patients less than 70 years that sustained a femoral neck fracture (FNF) treated with closed reduction and internal fixation (CRIF). ... -
Surgical treatment of obstructive sleep apnea : randomized controlled studies in children and adults
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-09-03)Obstructive sleep apnea (OSA) is a common disorder in both children and adults. In adults, OSA is a major health concern because it is highly prevalent and increases the risk for hypertension, cardiovascular disease, and ... -
The human ovary : a characterization of cell types and adverse ovarian side effects of chemotherapy
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-08-25)The human ovary has a major role in the body’s endocrine and reproductive system. Understanding its cell type composition is crucial in order to study underlying mechanisms of hormonal balance and ovarian follicle maturation ... -
Characterization of human gamma delta T cells in allogeneic hematopoietic stem cell transplantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-08-07)Over the last five decades, allogeneic hematopoietic stem cell transplantation (HSCT) has evolved rapidly, continuing to offer a cure for several hematological diseases. Nevertheless, associated life-threatening complications ... -
Hygiene at CT and MRI
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-05-26)Background: Preventing the spread of infections is a constant battle against microorganisms. Hospital-acquired infections (HAIs) with multidrug-resistant (MDR) bacteria are a global problem today and causes suffering for ... -
Outcome of gastric cancer surgery in Sweden
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-05-20)Gastric cancer worldwide is the fifth most common cancer and has the third highest cancer related mortality. Curative treatment includes surgical resection but comes with risk of complications and the optimal surgery ... -
Intralymphatic immunotherapy in allergic rhinitis : evaluating safety, efficacy and mechanisms
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-05-15)Allergic rhinitis (AR) deprives work capacity, social activities and quality of life, and costs the Swedish society about €1.3 billion annually. Allergen-specific immunotherapy (AIT) amends the symptoms and improves the ... -
Glutamine kinetics in critically ill patients
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2020-05-15)Critical illness, defined as a life-threatening organ failure, entails an extreme stress that results in a pathophysiology of its own. The abnormal metabolism of these patients causes a severe muscle wasting that is poorly ...