Now showing items 181-200 of 531

    • Innate mechanisms in upper airway inflammation with focus on epithelium and neutrophils 

      Arebro, Julia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-04-27)
      Mucosal inflammation is a key feature in allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP). The traditional idea of the epithelium as a simple barrier and neutrophils as a homogenous cell population, ...
    • Consequences of preterm birth on lung function, physical activity and exercise capacity 

      Svedenkrans, Jenny (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-04-21)
      The incidence of preterm birth is increasing worldwide. Some of the survivors of preterm birth will be affected by varying degrees of disabilities like lower cognitive or respiratory function. Moreover, the survivors will ...
    • Interprofessional collaboration in the ICU : facilitating progress in teams of learners 

      Conte, Helen (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-04-20)
      Background: Looking across research on health care education, few studies have explored processes of collaboration in interprofessional teams of participants at an interprofessional training unit (ITU) in intensive care. ...
    • Nasal epithelial cells : innate immunity and inflammation 

      Tengroth, Lotta (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-04-07)
      The surface epithelium that lines the nasal passages is often the first tissue in the airway to encounter inhaled pathogens. It collaborates closely with the innate immune system, a subsystem of the immune system that ...
    • Pediatric obstructive sleep apnea : evaluation of questionnaire and surgical treatment 

      Borgström, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-23)
      Obstructive sleep apnea (OSA) is a major pediatric health problem and is associated with potentially severe consequences if left untreated. Diagnosing OSA in children can be challenging since the clinical symptoms are very ...
    • Liver regeneration and function following portal vein occlusion and hepatectomy 

      Sparrelid, Ernesto (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2017-02-06)
      Background: Portal vein occlusion (PVO) and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) are two strategies employed to render patients with unresectable liver tumours resectable by ...
    • Studies of drug disposition in hemodialysis patients : impact of genetics, inflammation and vitamin D 

      Molanaei, Hadi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-12-28)
      Chronic kidney disease (CKD) patients are at a high risk for drug adverse effects due to accumulation of drugs, which normally are excreted via the kidneys. It is believed that drugs that are metabolized by the liver are ...
    • Risk of hospitalization and death due to bone fractures after breast cancer: a registry-based cohort study 

      Colzani, Edoardo; Clements, Mark; Johansson, Anna L V; Liljegren, Annelie; He, Wei; Brand, Judith S; Adolfsson, Jan; Fornander, Tommy; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-01)
      BACKGROUND: Bone fractures may have an impact on prognosis of breast cancer. The long-term risks of bone fracture in breast cancer patients have not been thoroughly studied. METHODS: Poisson regression was used to ...
    • Peptide and non-peptide biomarkers of mortality in patients with advanced chronic kidney disease 

      Sun, Jia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-23)
      Over the last decade, multiple studies have attempted to identify better risk prediction tools specific to the chronic kidney disease (CKD) population. In many cases, these studies have evaluated the use of various peptide ...
    • Cochlear implantation : experimental and clinical studies 

      Smeds, Henrik (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-18)
      Cochlear implantation makes hearing restoration possible in patients with severe to profound hearing loss. However, patients with residual hearing, where a cochlear implant may be combined with acoustic stimulation, and ...
    • Consequences of outsourcing referrals for radiological examinations 

      Tavakol Olofsson, Parvin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-14)
      Background: Demands for ever more effective healthcare and care accessibility for all patients continue to increase the workload in diagnostic radiology departments. Along with rapid developments in imaging technology which ...
    • Dialysis initiation and clinical outcomes in chronic kidney disease : role of education and biomarkers 

      Machowska, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-09)
      For patients with chronic kidney disease (CKD) who develop kidney failure, renal replacement therapy (RRT) with kidney transplantation is the best treatment option. But if this is not possible due to lack of organs or ...
    • Speech outcome in children born with cleft lip and palate treated with one-stage palate repair : aspects of function and environment 

      Nyberg, Jill (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-11-09)
      Introduction and aims: This project focused on speech outcomes at 5 and 10 years of age after two different surgical protocols and on peer perceptions of speech in children born with cleft palate. The aim was to gain ...
    • The evaluation, preoperative and operative aspects of abdominal wall reconstruction for giant ventral hernia 

      Clay, Leonard (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-10-19)
      BACKGROUND: The optimal method for surgical repair of giant ventral hernia remains to be determined. Different concepts for reinforcement have been used, which have decreased the risk for recurrence. However, the use of ...
    • Non invasive ventilation in people with cystic fibrosis 

      Rodriguez Hortal, Cecilia (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-10-14)
      Background: Cystic fibrosis (CF) is the most common life shortening autosomal recessive inherited disease affecting Caucasian people. The two main clinical characteristics of CF are progressive pulmonary disease and ...
    • Innate immunity and cardiac structure in chronic kidney disease 

      Wallquist, Carin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-26)
      The inflammatory state of chronic kidney disease (CKD) leads to increased susceptibility to infections and cardiovascular complications. In this thesis we aimed to investigate development of inflammatory properties at ...
    • Towards heart rate variability tools in p-health 

      Abtahi, Farhad (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-08)
      Heart rate variability (HRV) has received much attention lately, and several techniques for the analysis of HRV using time and frequency domains and non-linear methods have been developed. It has been shown that HRV can ...
    • Early obesity : family-based risk factors and treatment interventions 

      Ek, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-09-01)
      Background: The high prevalence of preschool obesity is a global concern. In order to support families through obesity interventions, we need a better understanding of underlying family-based risk factors. Specifically, ...
    • Drug and disease effects on the human brain studied by functional MRI 

      Engström Nordin, Love (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-08-19)
      Background: With the advent of magnetic resonance imaging (MRI) technology, various functional MRI (fMRI) techniques have become available for non-invasive neuroscientific studies and clinical diagnostics, which have led ...
    • Cerebral microbleeds and cognitive impairment 

      Shams, Sara (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2016-08-12)
      Background: With increasingly ageing populations comes an increased prevalence of cognitive impairment and dementia. The pathophysiology behind dementia is still unknown, and there is no cure. Microscopic bleeds in the ...