Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology: Recent submissions
Now showing items 121-140 of 531
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Neutrophil subsets in airway inflammation and hyperreactivity
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-11-06)Neutrophils are part of the first lines of defence against invading microbes. They play an essential role in antimicrobial host defence by recognizing microorganisms through the various receptors that can be expressed on ... -
Radiation dose-, contrast media- and image quality optimization in computed tomography
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-10-31)Computed tomography (CT) was introduced to medicine in the early 1970s, which brought slice imaging into wide use for the first time. Today, CT is an essential part of radiological diagnostics, and is used for a wide range ... -
The cholinergic anti-inflammatory pathway and heart rate variability with special reference to dialysis and renal denervation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-10-30)Background: The Cholinergic Anti-inflammatory Pathway (CAP) is a nerve-mediated circuit through which the vagus nerve regulates the activity of the inflammatory immune response. Injury, ischemia or infection activate the ... -
PET/CT with 18F-FDG and 68Ga-DOTATOC in pulmonary carcinoid imaging
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-10-11)Background: PET/CT, positron emission tomography combined with computed tomography, with 18F-FDG (2-deoxy-2-[18F]fluoro-D-glucose) is well established in oncological imaging. Pulmonary carcinoid tumours may have metabolic ... -
Chronic pancreatitis fibrogenesis : the role of TGFB pathway inhibitor Smad7 in the fibrosis development
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-10-02)Chronic pancreatitis is characterized by progressive inflammation, acinar atrophy and fibrosis. Transforming growth factor-B signaling (TGFB) is the most potent fibrogenic cytokine known, and its increased expression is a ... -
Massive transfusion in relation to obstetric hemorrhage : with special attention to placenta accreta
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-22)The overall purpose of this thesis was to assess risk factors, incidences, and complications of massive blood transfusions in relation to obstetric hemorrhage postpartum. Obstetric hemorrhage requiring blood transfusion ... -
Cardiovascular health in children and adolescents with obesity : prevalence, prediction and supervised exercise
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-19)Background: Cardiovascular disease (CVD) is a major cause of death worldwide and is preceded by a long process in which several cardiovascular (CV) risk factors are present, sometimes already in childhood. Some of these ... -
Borderline and locally advanced pancreatic cancer : redefining the biological and technical profile of the disease
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-09)Surgery is the only treatment modality that provides a chance for long-term survival in pancreatic cancer (PC). Thus, the current classification systems for PC are technically skewed to predicted the probability for surgical ... -
The dependency of image quality on acquisition protocol and image processing in chest tomosynthesis
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-02)The digital tomosynthesis (DTS) technique is a next generation of the old tomography technique, the use of which has been extended during the past decade. The interest in this technique has increased more and more in ... -
Teamarbete och informationsöverföring inom perioperativ vård : operationssjuksköterskans perspektiv
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-06-12)Bakgrund: Ett säkert genomförande av en kirurgisk intervention fordrar professionell kompetens, med såväl tekniska som icke-tekniska färdigheter. En säker vård kräver adekvat information om patienten och planerade ... -
Music therapy : an intervention effecting quality of life and health in children going through hematopoietic stem cell transplantation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-05-21)Hematopoietic stem cell transplantation (HSCT) is an established treatment for several types of leukemic, hematopoietic, and metabolic diseases. The child is isolated during 4-6 weeks, followed by extensive follow-up for ... -
Health related quality of life and swallowing problems in oesophageal cancer
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-25)Poor overall survival, swallowing problems and severe side-effects from multi-modality treatment characterize the situation of patients with oesophageal and gastro oesophageal junction carcinoma (GOJ). With the poor prognosis ... -
Quality of life, physical activity and bone health in idiopathic scoliosis
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-16)Idiopathic scoliosis is a deformation of the spine affecting 1-3% of children and adolescents during growth. Severe deformities may lead to pulmonary dysfunction, pain and decreased quality of life. The etiology of the ... -
The reactive stroma in pancreatic diseases
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-16)Stroma, or activated connective tissue, is a key component in both pancreatitis and pancreatic tumors. Acute pancreatitis (AP) is an inflammation of the pancreas which ranges from mild and local to systemic with severe ... -
Transarterial chemoembolization in primary liver and kidney malignancies
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-12)Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and the most current treatment for unresectable hepatocellular carcinoma is transarterial chemoembolization using drug-eluting beads (DEB-TACE). The ... -
Oral mucosa keratinocytes and their exosomes for epithelial tissue regeneration
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)Early tumors, including high grade dysplasia and intramucosal invasive cancer, of the esophagus can today be removed using endoscopic resection, often using a technique called endoscopic submucosal dissection (ESD). This ... -
Medical decision-making capacity among geriatric patients with and without dementia : communication-based approaches for assessment and facilitation
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)Introduction: Medical decision-making capacity concerns a patient’s cognitive abilities to make autonomous decisions regarding own person in medical contexts such as to choose treatment or accept/decline participation in ... -
Diabetic foot care in Sweden
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-02-11)Diabetes mellitus (DM) is a growing global disorder associated with several complications that include micro- and macrovascular disturbances. Conditions affecting the foot make up one of the major complications of the ... -
Outcome after surgery for isthmic spondylolisthesis and degenerative disc disease
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-01-17)Individuals with isthmic spondylolisthesis and lumbar degenerative disc disease may have low back and leg pain. Those with persistent symptoms non-responsive to conservative treatment are sometimes treated surgically. ... -
Utility of hybrid SPECT/CT in sentinel lymph node mapping, and [18]F FDG-PET/CT for treatment response evaluation in cancer patients
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-12-21)The Sentinel Lymph Node Biopsy (SLNB) method is currently well established in the staging of clinically node-negative breast cancer. However, there is some debate concerning the reliability of this method following previous ...