Now showing items 1-20 of 398

  • Borderline and locally advanced pancreatic cancer : redefining the biological and technical profile of the disease 

    Rangelova, Elena (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-09)
    Surgery is the only treatment modality that provides a chance for long-term survival in pancreatic cancer (PC). Thus, the current classification systems for PC are technically skewed to predicted the probability for surgical ...
  • The dependency of image quality on acquisition protocol and image processing in chest tomosynthesis 

    Jadidi, Masoud (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-08-02)
    The digital tomosynthesis (DTS) technique is a next generation of the old tomography technique, the use of which has been extended during the past decade. The interest in this technique has increased more and more in ...
  • Teamarbete och informationsöverföring inom perioperativ vård : operationssjuksköterskans perspektiv 

    Sandelin, Annika (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-06-12)
    Bakgrund: Ett säkert genomförande av en kirurgisk intervention fordrar professionell kompetens, med såväl tekniska som icke-tekniska färdigheter. En säker vård kräver adekvat information om patienten och planerade ...
  • Music therapy : an intervention effecting quality of life and health in children going through hematopoietic stem cell transplantation 

    Uggla, Lena (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-05-21)
    Hematopoietic stem cell transplantation (HSCT) is an established treatment for several types of leukemic, hematopoietic, and metabolic diseases. The child is isolated during 4-6 weeks, followed by extensive follow-up for ...
  • Health related quality of life and swallowing problems in oesophageal cancer 

    Sunde, Berit (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-25)
    Poor overall survival, swallowing problems and severe side-effects from multi-modality treatment characterize the situation of patients with oesophageal and gastro oesophageal junction carcinoma (GOJ). With the poor prognosis ...
  • Quality of life, physical activity and bone health in idiopathic scoliosis 

    Diarbakerli, Elias (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-16)
    Idiopathic scoliosis is a deformation of the spine affecting 1-3% of children and adolescents during growth. Severe deformities may lead to pulmonary dysfunction, pain and decreased quality of life. The etiology of the ...
  • The reactive stroma in pancreatic diseases 

    Norberg, Jessica (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-04-16)
    Stroma, or activated connective tissue, is a key component in both pancreatitis and pancreatic tumors. Acute pancreatitis (AP) is an inflammation of the pancreas which ranges from mild and local to systemic with severe ...
  • Transarterial chemoembolization in primary liver and kidney malignancies 

    Karalli, Amar (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-12)
    Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and the most current treatment for unresectable hepatocellular carcinoma is transarterial chemoembolization using drug-eluting beads (DEB-TACE). The ...
  • Oral mucosa keratinocytes and their exosomes for epithelial tissue regeneration 

    Sjöqvist, Sebastian (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)
    Early tumors, including high grade dysplasia and intramucosal invasive cancer, of the esophagus can today be removed using endoscopic resection, often using a technique called endoscopic submucosal dissection (ESD). This ...
  • Medical decision-making capacity among geriatric patients with and without dementia : communication-based approaches for assessment and facilitation 

    Thalén, Liv (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-03-07)
    Introduction: Medical decision-making capacity concerns a patient’s cognitive abilities to make autonomous decisions regarding own person in medical contexts such as to choose treatment or accept/decline participation ...
  • Diabetic foot care in Sweden 

    Wennberg, Linda (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-02-11)
    Diabetes mellitus (DM) is a growing global disorder associated with several complications that include micro- and macrovascular disturbances. Conditions affecting the foot make up one of the major complications of the ...
  • Outcome after surgery for isthmic spondylolisthesis and degenerative disc disease 

    Endler, Peter (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2019-01-17)
    Individuals with isthmic spondylolisthesis and lumbar degenerative disc disease may have low back and leg pain. Those with persistent symptoms non-responsive to conservative treatment are sometimes treated surgically. ...
  • Utility of hybrid SPECT/CT in Sentinel Lymph Node mapping, and 18F FDG-PET/CT for treatment response evaluation in cancer patients. 

    Gabrielson, Stefan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-12-21)
    The Sentinel Lymph Node Biopsy (SLNB) method is currently well established in the staging of clinically node-negative breast cancer. However, there is some debate concerning the reliability of this method following previous ...
  • On bioenergetic failure in septic shock : lactate kinetics and mitochondrial respiration 

    Grip, Jonathan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-12-20)
    Septic shock, a dysregulated immune response to an infection, is a major cause of mortality and morbidity in patients treated in intensive care units (ICUs). The cause of the organ dysfunction seen in sepsis is still not ...
  • The role of thyroid stimulating hormone receptor and novel candidate genes FAM13a and POM121c in adipocyte dysfunction 

    Lundbäck, Veroniqa (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-19)
    This thesis aimed to investigate the role of thyroid stimulating hormone receptors (TSHRs) in adipose tissue (AT) and their role in AT dysfunction and obesity-related metabolic complications. Furthermore, we aimed to ...
  • Radiomics in cancer prognosis : applications and limitations of quantitative texture analysis 

    Zhang, Yi-Hua (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-16)
    Medical imaging has become an integral part of clinical diagnostics since the discovery of X- rays at the end of the 19th century. Recent advances in computing power have opened up the possibility to extract quantitative ...
  • Exploring the role of mesenchymal stromal cells in endometriosis 

    Abomaray, Fawaz (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-16)
    Endometriosis is a chronic inflammatory disease where there is growth of endometrial tissue in ectopic sites, most commonly within the pelvic cavity. The major symptoms of this disease are chronic pelvic pain and infertility. ...
  • Cellular consequences of preterm birth : telomere biology, immune development and oxidative stress 

    Henckel, Ewa (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-15)
    Preterm infants are at risk for oxidative stress just by being born. The extra-uterine environment is relatively oxygen-rich, their antioxidant defenses are immature, diseases and treatments in the neonatal period will ...
  • Auditory organotypic cultures and progenitor cell implantation 

    Kaiser, Andreas (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-15)
    According to the WHO, about 5 % of the world’s population suffers from disabling hearing loss. In people above the age of 65 the number is more than 30 %. Common effects of this condition are poor speech discrimination and ...
  • Nutritional intakes over time and perioperative nutrition in extremely preterm infants. 

    Westin, Vera (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2018-11-08)
    Background Despite improvements in nutrition practice during the last decades, problems still exist in meeting estimated nutritional needs, especially for extremely preterm (EPT) infants. Today, it is still not known how ...