Now showing items 21-40 of 526

    • Stuttering in young females and males 

      Samson, Ineke (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-10-27)
      Stuttering is a relatively common speech disorder and most people have met someone who stutters. Symptoms of stuttering are repetitions, prolongations and blocks that stop the natural flow of speech. However, the symptoms ...
    • Level with me! Exploring patient participation in short-term clinical encounters in team-based settings 

      Dubois, Hanna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-10-21)
      Background: Patient participation has been described as patients’ opportunities for involvement in different parts of their care. Benefits, including improved patient safety, health outcomes and patient satisfaction have ...
    • Fungal colonization and infection in cystic fibrosis : prevalence, consequences and intervention 

      Al Shakirchi, Mahasin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-30)
      Background: Cystic fibrosis (CF) is an inherited progressive disease affecting multiple organs. The main cause of death in CF is related to the respiratory complications. Inflammation and infection, triggered by colonizing ...
    • Diagnostic and predictive factors in pancreatic cancer : clinical and translational studies 

      Kordes, Maximilian (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-28)
      Aims: The aim of Study I was to assess the effectiveness of chemotherapy for patients with advanced pancreatic cancer in a real-world setting. Study II aimed to evaluate the utility of a clinical decision support system ...
    • Development of new blood banking strategies for processing and storage of red blood cell components 

      Larsson, Linda (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-26)
      The field of red blood cell (RBC) components has been quite uneventful during the last few decades, save for the experimental exploration of alternative additive solution compositions. The reason is likely that the RBC ...
    • Perspectives on screening strategies for early detection of childhood hearing impairment 

      Mackey, Allison (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-20)
      The aims of this thesis were to assess the status of childhood hearing screening programmes, primarily in Europe, and to evaluate their performance against the parameters that make up a childhood hearing screening programme, ...
    • Allergic rhinitis and intralymphatic vaccination : immune response and tolerance 

      Hjalmarsson, Eric (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-14)
      The overall goal of this thesis was to study novel immunological mechanisms for the development of pollen-induced allergic rhinitis (AR) and to evaluate the clinical response in combination with immunological changes in ...
    • Invasive intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma : a comparison in clinicopathology and long-term outcome 

      Holmberg, Marcus (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-09)
      Background: The resections for both pre-malignant and invasive intraductal papillary mucinous neoplasm (inv-IPMN) have increased the last decades. Long term outcome, and the impact of adjuvant chemotherapy, non-regional ...
    • Babbling, speech and language in children with neurological disabilities : development, validity of measures and effect of intervention 

      Nyman, Anna (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-09-08)
      Children with neurological disabilities (ND) such as cerebral palsy, Down syndrome or other genetic syndromes often have speech and language disorder. In Sweden, children with ND often receive team-based habilitation ...
    • Physical activity and obesity prevention in early childhood 

      Bergqvist-Norén, Linnea (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-08-18)
      Background: Obesity is a worldwide epidemic with adverse health outcomes and finding effective interventions to prevent this disease is crucial. Physical activity (PA) has beneficial health effects and is often included ...
    • Investigation of tumour/stroma crosstalk in pancreatic cancer by an advanced 3D co-culture model 

      Liu, Xinyuan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-06-01)
      Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies all over the world. This dire situation is mainly attributable to the dense desmoplasia in the tumour microenvironment (TME) and almost complete ...
    • Exploring early development and regenerative medicine using CRISPR/Cas9 

      Winblad, Nerges (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-30)
      With their intrinsic capacity to self-renew and their potential to differentiate to specialized tissues, human embryonic stem cells (hESCs) have many applications in the fields of cell therapy and developmental biology. ...
    • Mobile health interventions and cardiorespiratory fitness in pediatric obesity 

      Johansson, Linnea (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-25)
      Pediatric obesity treatment, preferably at an early age, is important since obesity severely impairs present and future health. Current approaches for lifestyle changes do not provide results of clinical relevance, and ...
    • Biological ageing and kidney transplantation 

      Erlandsson, Helen (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-24)
      The aim of this thesis was to investigate the impact of biological ageing in patients with chronic kidney disease, the effect of kidney transplantation on biological ageing and longterm outcome in patients with kidney ...
    • Assessment and differential diagnosis in childhood apraxia of speech 

      Rex, Susanne (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-24)
      Introduction and aims: Childhood Apraxia of Speech (CAS) is a disorder of speech motor planning and programming affecting the ability to transform the linguistic code into movements needed for intelligible speech. CAS is ...
    • Students’ and supervisors’ experiences of supervision and training in clinical learning environment 

      Sellberg, Malin S (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-19)
      Clinical training for health profession students is important prior to commencing their future professions. The literature describes a tension between the education assignment and patient care in clinical environments with ...
    • Sex hormones in gastric mucosal physiology and the development of oesophageal, gastric and colorectal adenocarcinoma 

      Shore, Richard (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-19)
      The aim of this thesis was to continue to test the hypothesis that sex hormones play some part in the aetiology and seem to protect women from the development of oesophageal, gastric, and colorectal adenocarcinoma. All ...
    • Renal function decline and optimized planning for kidney replacement therapy 

      Hahn Lundström, Ulrika (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-18)
      Chronic Kidney disease (CKD) is an increasing health problem world-wide, and the prevalence increases with age. CKD is a life-threatening condition, with high risk of cardiovascular disease and mortality. Patients with ...
    • Long-term outcome after hypothermia-treated hypoxic-ischaemic encephalopathy 

      Robertsson Grossmann, Katarina (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-13)
      Hypoxic-ischaemic encephalopathy (HIE) is a major cause of acquired brain injury in newborn infants. It is a potentially life-threatening condition that leaves survivors at substantial risk of life-long debilitating sequelae ...
    • Clinical use of prognostic markers in head and neck cancer 

      Landin, David (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-05-12)
      Head and neck cancer (HNC) is a heterogeneous group of tumors where squamous cell carcinoma is the most dominant. In 2020, 1640 new cases of HNC were reported in Sweden which accounted for 2.3% of the total cancer incidence. ...