Now showing items 1-20 of 636

    • The role of oxysterols in neurodegeneration : implications for cognitive function, maternal effects, and sex-specific differences 

      Latorre Leal, María (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-03-26)
      It is widely proven that an imbalance of cholesterol homeostasis within the brain is linked to several neurodegenerative diseases and in particular, Alzheimer's disease (AD). The brain, an organ highly enriched with ...
    • Determinants of age-related brain iron accumulation and links to neurocognitive functions 

      Gustavsson, Jonatan (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-02-14)
      Iron is crucial for development and normal functioning of the brain. With increasing age, it accumulates in the cells and can cause irreparable damage, affecting both the structure and function of the brain. Despite these ...
    • Alcohol consumption and cognition 

      Tsevis, Theofanis (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-01-31)
      There is evidence that alcohol consumption is increasing in recent decades, including both male and female older individuals. Excessive alcohol use can affect various functions, of which alcohol-related liver failure and ...
    • Protein and MRI profiling of genetic frontotemporal dementia 

      Ullgren, Abbe (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-01-17)
      Frontotemporal dementia (FTD) is a group of neurodegenerative diseases with a wide range of symptoms such as loss of inhibition and social cognition, language impairment and motor dysfunction. Genetic FTD, characterized ...
    • Enhanced mobilisation and physical rehabilitation after abdominal cancer surgery : feasibility, effects, and experiences 

      Karlsson, Patrik (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-01-11)
      Cancer incidence is growing worldwide and, as advances in diagnostics, treatment, and rehabilitation are made, the numbers of cancer survivors are also increasing. Therefore, there is a need to find and evaluate methods ...
    • Aspects on heart failure and drug treatment in geriatric patients 

      Reimers Wessberg, Marianne (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-01-10)
      Background: Patients with chronic heart failure (HF) are very common in geriatric care, but the prevalence of different types of HF and comorbidities, as well as the nature of investigations, treatment, planning and outcome ...
    • Tau pathology in Alzheimer's disease and other dementias : translational approach from in vitro autoradiography to in vivo PET imaging 

      Malarte, Mona-Lisa (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-12-27)
      Tauopathies, including Alzheimer's disease (AD), corticobasal degeneration (CBD), and progressive supranuclear palsy (PSP), are complex neurodegenerative disorders characterized by the pathological accumulation of tau ...
    • Identifying individuals at risk of fragility fractures in a dental setting 

      Elleby, Charlotta (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-12-15)
      Introduction: The increasing life expectancy is only positive if the added years are healthy years. Fragility fractures are most common in older adults, and they can result in lowered quality of life and high costs for the ...
    • The single leg squat in clinical testing : aspects of reliability, validity, and associated factors 

      Ressman, John (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-12-13)
      Background: The Single Leg Squat (SLS) test is a functional test widely used in clinical settings to examine and evaluate rehabilitation goals. Research indicates that the SLS is reliable when the knee relative to the foot ...
    • Independence in activities after injury in humanitarian settings : assessment, change over time and associated factors 

      Gohy, Bérangère (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-11-15)
      Background: Injury represents a significant burden in humanitarian settings, overwhelming the limited trauma care resources. Trauma care in these settings mainly focuses on saving lives and limbs, and not on recovery in ...
    • Students' perceptions of interprofessional learning and virtual patients in primary healthcare 

      Tran, Carrie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-11-02)
      Background: The benefits of interprofessional education in healthcare, such as improved communication and ability to teamwork, are well known globally. There is a need to prepare students for interprofessional collaboration ...
    • Assessment of frailty in old people with multimorbidity 

      Lindh Mazya, Amelie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-11-02)
      Background: As the population grows older, understanding and management of multimorbidity and frailty will become increasingly important. There is no consensus on how to define or measure frailty and awareness of frailty ...
    • Make My Day : exploring engaging occupations in stroke prevention and promotion of health 

      Mälstam, Emelie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-11-01)
      Background: Stroke is one of the major causes of disease burden worldwide. Most stroke cases are attributed to modifiable risk factors, such as high blood pressure, overweight, smoking, physical inactivity, and poor diet, ...
    • Evolving reablement through occupational perspectives and welfare technology in home care 

      Assander, Susanne (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-10-25)
      Rationale: Sweden is encountering dual societal challenges characterised by a rapidly ageing population and a diminishing home care workforce, leading to strained resources, which potentially can impact the quality of care. ...
    • Narrative relations : resources for meaning-making and person-centred practices in geriatric care 

      Herulf Scholander, Lisa (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-10-02)
      Narrative approaches in healthcare have attracted a lot of academic attention, suggesting a strong potential in narrativity to help shift healthcare towards more compassionate and person-centred practices. Yet, there is ...
    • Characterization of proteins involved in disease progression in Alzheimer disease 

      Axenhus, Michael (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-09-29)
      Alzheimer disease (AD) is a neurodegenerative disease and severe neuronal loss is already taking place at the time of diagnosis. AD affects nearly 50 million people worldwide and the incidence is expected to rise ...
    • Depression and chronic diseases in old age : understanding their interplay for better health 

      Triolo, Federico (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-09-27)
      Late-life depression is intricately linked with somatic diseases. This thesis aimed to systematically explore this complex interplay. Specifically, we investigated: 1) the symptom-level interconnectedness between depression ...
    • Cardiovascular health, orthostatic hypotension, and cognitive aging 

      Xia, Xin (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-09-20)
      Cardiovascular health (CVH) plays an important role in dementia development. Ideal CVH, defined by Life’s Simple 7 (LS7), has been associated with a lower risk of dementia in older adults. Orthostatic hypotension (OH) may ...
    • Individualised care for patients with breast or prostate cancer aided by an interactive app : a frame of process evaluation 

      Crafoord, Marie-Therése (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-08-25)
      Background: Patients receiving outpatient cancer treatment often experience distressing symptoms and unmet needs. Collecting patient-reported outcomes via apps (ePROs) facilitates patient-clinician communication regarding ...
    • Mental stimulation and multimodal trials to prevent cognitive impairment and Alzheimer ́s disease 

      Rydström, Anders (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-08-17)
      Theoretical models of dynamic biomarkers underlying the development of Alzheimer´s Disease (AD) acknowledge that there is inter-individual variability in the cognitive performance associated with any level of AD pathology. ...