Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society: Recent submissions
Now showing items 21-40 of 617
-
Drug discovery targeting non-amyloid pathways in Alzheimer’s disease
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-04-02)Alzheimer’s disease (AD) is the most common form of dementia with almost 50 million people affected and unfortunately, no cure or treatment to halt the disease progression is available. In the hereditary forms of AD, an ... -
Development of novel synthetic lung surfactants for treatment of respiratory distress syndrome
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-02-26)Pulmonary surfactant is a complex mixture of lipids and specific proteins found in the alveoli and its main role is to reduce the surface tension of the alveolar air/water interface, thereby preventing lung collapse. ... -
Patient safety in primary and emergency care
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-02-17)This thesis explores aspects of risk and safety in health care. Patient safety is about preventing harm to patients. A perspective of resilience is used, which is a proactive approach to making care safer. Resilient ... -
Voices to remember : persons' and family members' experiences of living with neurocognitive disorders and related symptoms
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-02-13)Persons with cognitive impairment are often encouraged by society and family to seek a cognitive assessment and receive a timely dementia diagnosis (dementia is also known as a major neurocognitive disorder). A cognitive ... -
A star is born : development of NT* as a new biotechnological tool based on the mechanism of pH dependent dimerization of the spidroin N-terminal domain
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-02-06)Proteins are widely used in research and in the pharmaceutical industry but the production of recombinant protein can be tedious, costly and time-consuming due to unwanted aggregation. Strategies to circumvent aggregation, ... -
Traditional yoga and clinical burnout : quality of life and biomarkers before and after treatment
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2020-01-23)Background. Stress-related disorders including clinical burnout (CB) are one of the main causes of sickness absenteeism in many Western countries. Little is known about the situation of CB patients, and objective markers ... -
The role of atrial fibrillation in cognitive aging : a population-based study
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-11-18)The role of atrial fibrillation (AF) in brain and cognitive aging (e.g., cognitive decline and dementia) is still unclear. In this doctoral thesis, we aimed to investigate the temporal trends and potential determinants ... -
Well begun is half done : preoperative physical performance & home-based exercise in older adults undergoing abdominal cancer surgery
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-11-07)The proportion of older adults continues to increase in Sweden and globally. Consequently, we are seeing an increase in diseases associated with aging, such as cancer. The primary treatment for abdominal cancer is surgery, ... -
Psychosocial well-being in bereavement among family members with a special focus on young adults who have lost a parent to cancer
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-10-30)Introduction: The loss of a loved one is a distressing life event for family members which often affects psychosocial well-being. Young adults who have lost a parent may be a particularly vulnerable group of bereaved ... -
Predictors and consequences of injurious falls among older adults : a holistic approach
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-10-04)The field of research on falls among older adults is well studied. Despite this, there are some knowledge gaps that need to be addressed: 1) research studying injurious falls, as opposed to any falls; 2) knowledge on sex ... -
Energy expenditure and accelerometer cut-points for sedentary behavior and physical activity in spinal cord injury : implication for guiding and prevention
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-09-13)Background: A motor-complete spinal cord injury (SCI) alters the prerequisites for physical activity (PA) and subsequently energy expenditure. Persons with SCI above thoracic level six have a compromised physiological ... -
Dopamine, decision-making, and aging : neural and behavioural correlates
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-09-12)On any given day, we make tons of decisions. These can be as simple as deciding how to dress or what to eat, or more complex, such as whether to spend or invest money. Good decision-making involves being able to select the ... -
Too much, too late? Drug prescribing for older people near the end of life
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-08-28)Background. The burden of drugs prescribed to older persons at the end of life has recently drawn increasing scrutiny. Growing evidence suggests that patients with lifelimiting diseases and poor prognosis are prescribed ... -
Multimodal imaging : functional, structural, and molecular brain correlates of cognitive aging
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-08-26)Aging is associated with a decline in many (but not all) cognitive abilities. Although it remains largely unknown how changes in brain integrity relate to cognitive deficits, these changes are likely expressed across ... -
Interdisciplinary rehabilitation in patients with chronic pain : prognostic factors and effectiveness
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-08-01)Interdisciplinary multimodal pain rehabilitation (IMPR) is currently considered best practice for combatting chronic pain. However, it is believed that health-related outcomes could be improved with more adequately tailored ... -
Everyday technologies and public space participation among people with and without dementia
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and SocietyMalmö University, 2019-06-12)BACKGROUND: Occupational therapists support everyday technology use; however, it is necessary to consider the challenges that people with dementia encounter with everyday technologies when participating in various places ... -
CADASIL : a pure model for studying cerebral small vessel disease
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-05-23)Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is caused by a mutation on the NOTCH3 gene. The pathological driver behind this disease is the loss of vascular smooth ... -
Impact of psychosocial working conditions on health in older age
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-05-09)Work takes up a large proportion of time in our adult lives, thus possibly making it an important determinant of health. This doctoral thesis aimed to investigate the impact of psychosocial working conditions on health in ... -
Participation in everyday life after stroke : development and evaluation of F@ce – a team-based, person-centred rehabilitation intervention supported by information and communication technology
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-05-07)AIM: The general aim of this thesis was to generate knowledge about how Information and Communication technology (ICT) could be used in the rehabilitation process after stroke in order to develop and evaluate the feasibility ... -
Impact of cardiovascular and neuropsychiatric multimorbidity on older adults' health
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2019-04-17)Multimorbidity, the presence of two or more chronic diseases in one person, is common in older people, and associates with a number of negative outcomes. In this thesis, we propose a methodology to assess and measure ...