Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society: Recent submissions
Now showing items 41-60 of 701
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eHealth support for physical activity and exercise training in people with COPD
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-05-23)Aim: The overall aim of this thesis was to apply user involvement and co-creation to generate knowledge on how an eHealth tool, including physical activity and exercise training, for people with chronic obstructive pulmonary ... -
Taking physical rehabilitation after abdominal cancer surgery further : by enhanced recovery and physical activity
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-05-11)The overall aim with this thesis was to increase knowledge of standardised methods for individualised mobilisation and rehabilitation after abdominal cancer surgery. Concerning mobilisation, both effect, and patients’ ... -
Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-05-06)Alzheimer’s disease (AD), the most common neurodegenerative disease, is characterized by two pathological hallmarks: extracellular amyloid-beta peptide (Aβ) plaque depositions and neurofibrillary tangles (NFTs) composed ... -
Health inequalities in care for persons with dementia
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-04-28)Health inequality is defined as any difference, disparity, or variation in all health-related aspects of individuals and groups. The World Health Organization regards ensuring equal access to promotion, prevention, ... -
To participate or not : decision-making and experiences of individuals invited to screening for colorectal cancer
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-03-31)Background: Colorectal cancer (CRC), the third most common and second most fatal cancer worldwide, can to a large extent be prevented by organised population-based screening. In Sweden, organised CRC screening only operates ... -
Methods for the analysis and characterization of brain morphology from MRI images
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-03-04)Brain magnetic resonance imaging (MRI) is an imaging modality that produces detailed images of the brain without using any ionizing radiation. From a structural MRI scan, it is possible to extract morphological properties ... -
Genetic code expansion in neurons for studying pathogenic mechanisms of Alzheimer disease
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-02-03)Every three seconds a new patient is diagnosed with Alzheimer disease (AD). The primary risk factor for this irreversible, progressive brain disorder is old age. It is a growing health concern, not only for the patients, ... -
Motor and cognitive abilities in Parkinson’s disease with a brain activity perspective : performance at baseline and the effects of a balance training program
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-01-18)Background: Around one per cent of the population over 60 years of age have Parkinson’s disease (PD). PD is a progressive and complicated disease presenting a wide range of symptoms. More knowledge of the common impairments ... -
Neuropathic pain in an elderly population of an urban area of Iran with a special focus on carpal tunnel syndrome : epidemiological aspects, clinical characteristics, and non-surgical therapy
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2022-01-14)Background: People are getting older, and aging problems and disorders are increasing fast. Knowing the rates, causes, symptomatology, treatment, relief, and prognosis of associated disorders can help and facilitate the ... -
Factors associated with behavioral and psychological symptoms of dementia
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-12-22)Most people with dementia suffer behavioral and psychological symptoms (BPSD). These symptoms add to caregiver stress and accelerate cognitive decline. The etiology of BPSD is complex, with multiple factors influencing ... -
Biomarkers in frontotemporal dementia : findings from the GENFI study
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-12-21)Frontotemporal dementia (FTD) is a group of neurodegenerative diseases including a wide range of clinical phenotypes, neuropathological hallmarks, and genetic causes. People with FTD typically present with deficits in ... -
Sickness absence among patients with chronic pain in Swedish specialist healthcare
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-12-20)Background: Chronic pain beyond three months is a global public health problem. Every third adult suffers from a chronic pain condition, resulting in a socioeconomic burden that corresponds to 3-10% of gross domestic product ... -
Translational studies on Alzheimer’s disease : a focus on cholesterol metabolism, thioredoxin-80 and microglia function
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-26)Disturbances in cholesterol metabolism and inflammatory processes may have a negative impact on brain health. These two aspects are considered to be signs of early changes in Alzheimer’s Disease (AD). However, clear molecular ... -
Alzheimer disease : a super-resolved picture of the amyloid β-peptide producing machinery
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-26)Alzheimer disease (AD) is the most common neurodegenerative disease, influencing 40 million patients in the world. Pathologically, AD is hallmarked by intracellular tau tangles and extracellular Amyloid-β peptide (Aβ) ... -
Beyond exhaustion and pain : the intertwinement of health and suffering among women and mothers
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-23)Aims: The overall goal of the thesis was to understand and to conceptualize health and suffering among women living with exhaustion and long-lasting pain, with a particular focus on motherhood. Methods: The thesis’ ... -
The Stockholm spinal cord uro study
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-22)Aims: To evaluate urinary tract function and complications in a regional population with chronic traumatic spinal cord injury (SCI), to estimate risk profiles for recurring complications and improve follow-up for neurogenic ... -
CYP3A and lipids in health and disease : in females and males
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-12)Sex and gender differences in the pharmacokinetics-and dynamics of drugs, have been known for centuries. Women have been regarded as different - a 70 kg male has been the norm in medicine. In the context of clinical studies, ... -
Better all the time? Trends in health and longevity among older adults in Sweden
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-11-01)Background: The health status of the aging population has become one of the major public health concerns today, as the number of older people increases in both absolute and relative terms and life expectancy continues to ... -
Human spinal cord models for development of spinal cord injury repair strategies
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-10-29)There is still no available cure for human spinal cord injury (SCI). After a SCI, neural cell loss, excitotoxicity, neuroinflammation, astrocytic and oligodendrocytic derived inhibiting factors contribute to a non-permissive ... -
Students’ workplace learning in primary health care : learning from patients
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-09-24)Background: Facilitation of patients’ participation in own care is considered key component to achieve a person-centered, high-quality care delivery. Person-centered care, including communication techniques and patient-centered ...